DMSO: The Real Miracle Solution

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Due to the nuclear alert in Japan and its likelihood to affect the United States and other parts of the world, I decided to carry this article which I wrote for the Dot Connector Magazine‘s issue N. 12.

First, a little bit of background.

Radiation produces free-radicals (“inflammatory molecules”) that damage cells that make up tissues such as organs, glands, muscles, and bones. Besides causing the cells to age more quickly they also become distorted, or mutated, creating cancers such as leukemia, anemia, birth defects, and other diseases.

Sulfur has a long history of use as an antidote for acute exposure to radioactive material. DMSO is the classical sulfur compound. A Japanese study showed that even low concentrations of DMSO had radio-protective effects through the facilitation of DNA double-strand break repair, providing protection against radiation damage at all cellular levels in the whole body.

Remember that boosting your body’s detox capabilities and overall anti-oxidants levels is a key to survive in these stressful times. Being on a detox diet is crucial to regain health in a toxic environment. Our extensive experience and research shows that those on a no grain/low carb (no gluten) and non dairy diet fare MUCH better.

For more information on how to protect yourself from nuclear radiation, see:

Treatments for Nuclear Contamination

Iodine Treatments for Radiation Exposure

Greenmedinfo.com – Radioprotective

DMSO is an effective pain killer, blocking nerve conduction fibers that produce pain. It reduces inflammation and swelling by reducing inflammatory chemicals. It improves blood supply to an area of injury by dilating blood vessels and increasing delivery of oxygen and by reducing blood platelet stickiness. It stimulates healing, which is a key to its usefulness in any condition. It is among the most potent free radical scavengers known to man, if not the most potent one.

In 1866, Russian scientist Alexander Saytzeff isolated a most curious and peculiar chemical compound. It was crystalline, odor-less, non-toxic and had a garlic-like taste when consumed. At the time, Saytzeff had no way to predict that his discovery was going to prove highly controversial throughout its entire medical history, that it was going to be tested in thousands of studies, providing miraculous relief in numerous patients.

I’m talking here about dimethyl sulfoxide (DMSO), an organic sulfur compound which was used only as an industrial solvent, that is, until its medical properties were discovered in 1963 by a research team headed by Stanley W. Jacob, MD.
DMSO is a by-product of kraft pulping (the “sulfate process”) which converts wood into wood pulp consisting of almost pure cellulose fibers. As industrial as it may sound, the process simply entails a treatment of wood chips with a mixture of sodium hydroxide and sodium sulfide, known as white liquor, breaking the bonds which link lignin (from the Latin word lignum, meaning wood) to the cellulose.

DMSO is useful as a pain reliever, in burns, acne, arthritis, mental retardation, strokes, amyloidosis, head injury, scleroderma, it soothes toothaches, eases headaches, hemorroids, muscle strains, it prevents paralysis from spinal-chord injuries, it softens scar tissues. In fact, it is useful in well over 300 ailments and it is safe to use. You would think that a compound that has so many alleged uses and benefits will be automatically suspect, but careful examination of its properties and the data available will shed some light in this miraculous chemical.

Sulfur: The Stuff of Life

DMSO is an intermediate product of the global Sulfur Cycle which distributes bioavailable sulfur for all animal and plant life (Parcell, 2002). Sulfur compounds are found in all body cells and are indispensable for life, they are needed for a number of chemical reactions involved in the detoxification of drugs and other harmful toxins, and they have potential clinical applications in the treatment of a number of conditions such as depression, fibromyalgia, arthritis, intersticial cystitis, athletic injuries, congestive heart failure, diabetes, cancer, and AIDS (Parcell, 2002). Among the sulfur compounds, DMSO is probably the one that has the widest range and greatest number of therapeutic applications ever shown for any other single chemical. It has around 40 pharmacological properties that may be beneficial in the prevention, relief or reversal of numerous diseases (Morton, 1993).

Someone complained to Dr. Jacob of a splitting headache and gave him permission to apply some DMSO after hearing of its capabilities. The headache was gone in minutes, came back in four hours, and left for good after DMSO was applied a second time. Used for one purpose, sometimes it did another; put on a cold sore, within a few hours it cleared up a woman’s sinusitis. A woman who had had a stroke found after DMSO was painted on her painful jaw that she could now write with her paralyzed hand and could walk better. (Haley, 2000)

Therapeutic Properties

DMSO is an effective pain killer, blocking nerve conduction fibers that produce pain. It reduces inflammation and swelling by reducing inflammatory chemicals. It improves blood supply to an area of injury by dilating blood vessels and increasing delivery of oxygen and by reducing blood platelet stickiness. It stimulates healing, which is a key to its usefulness in any condition. It is among the most potent free radical scavengers known to man, if not the most potent one. This is a crucial mechanism since some molecules in our bodies produce an unequal number of electrons and the instability of the number causes them to destroy other cells. DMSO hooks on to those molecules and they are then expelled from the body with the DMSO.

 

 


DMSO also penetrates the skin and the blood-brain barrier with ease, penetrating tissues, and entering the bloodstream. Furthermore, DMSO protects the cells from mechanical damage and less of it is needed to achieve results as time passes as oppossed to most pharmaceuticals where increasing doses are required. It has a calming effect in the central nervous system and it reaches all areas of the body, when absorbed through the skin, including the brain. That is, DMSO applied to one area often leads to pain relief in some other location due to its systemic effect.

It acts as a carrier for other substances or drugs and it also potentiates their effect. In fact, certain drugs dissolved in DMSO, such as corticoids, antibiotics and insulin, may be used in a lower dose than usual without reducing their therapeutic efficacy and in addition, their undesirable side effects are greatly diminished. Also, drugs are able to pass through the blood-brain barrier which is usually impenetrable.

DMSO promotes the excretion of urine and functions as a muscle relaxant. It boosts the immune system, increasing the production of white cells and macrophages that destroy foreign material and pathogens in the body. It also has anti-bacterial, anti-viral and anti-fungal properties. DMSO also increases the permeability of cell membranes, allowing a flushing of toxins from the cell.

DMSO has radioprotective properties against lethal and mutagenic effects of X-rays in cells, cellular systems and whole animals. It also has cryoprotective properties, meaning that it is capable of protecting against injury due to freezing.
DMSO has also been shown to have anti-cholinesterase properties (Sams, 1967), in other words, it inhibits an enzyme from breaking down acetylcholine, increasing both the level and duration of action of this important neurotransmitter. Acetylcholine is responsible for learning and memory and is also calming and relaxing. Acetylcholine is also a major factor in regulating the immune system, acting as a major brake on inflammation in the body.

As a source of sulfur, DMSO aids in heavy metal detoxification. Sulfur binds with toxic heavy metals (mercury, lead, aluminum, cadmium, arsenic, nickel) and eliminates them via urination, defecation and sweating.

FDA and Big Pharma Obstacles

DMSO is sold in health food stores, mail-order outlets, on the Internet, and in most countries around the world. It is used by millions for its health benefits yet in the U.S., DMSO has FDA approval only as a preservative of stem cells, bone marrow cells, and organs for transplant, and for interstitial cystitis – a painful inflammatory condition of the bladder which is very difficult to treat with other therapies.

That DMSO has not found favor as a remedy for other medical conditions is partly due to the inability to test it in double-blind experiments. Blind studies, as the name suggests, requires that a study be done without knowing which patient is taking the placebo or the drug. In the case of the DMSO, a blind study is impossible since the peculiar garlic-like taste and smell (no matter the route of application) gives it away and no satisfactory placebo could be devised that would mimic this particular effect of DMSO (Steinberg, 1967).

The FDA and big pharma would prefer we remain dependent on their drugs.


If you search for DMSO on the U.S. National Library of Medicine (pubmed.gov), you’ll get almost 30,000 indexed results, making it one of the most studied compounds of our time. Yet, we are led to believe that DMSO can’t pass the required regulations for its approval in other medical conditions even though its effectiveness and low toxicity profile is unquestionable.

You see, DMSO is a common chemical that can be manufactured cheaply. No drug company can get an exclusive patent since it is also a natural compound, therefore there is no significant financial return. In fact, an executive of a major drug company is quoted as saying, “I don’t care if DMSO is the major drug of our century and we all know it is, it isn’t worth it to us” [CBS TV show 60 minutes with Mike Wallace, The Riddle of DMSO]. If DMSO were to be approved by the FDA, it would be competetive and drug companies would be unable to hold the patents. In the words of the director of the Bureau of Drugs of the FDA, J. Richard Crout, M.D., “DMSO is a low toxicity and safe compound (…) I think that it is a fact of life that drug companies are not going to invest in something unless they think there is some financial return” [CBS TV show 60 minutes with Mike Wallace, The Riddle of DMSO].

Despite restrictions on the use of DMSO, thousands of Americans purchase it on the ‘black market’ each year, its popularity due not to publicity, but rather ‘word of mouth’. When you have something that relieves all kinds of ailments, including some life-threatening ones, people naturally recommend it to friends and family!

In Perspective

In the 1960s, research with DMSO on humans was temporarily halted after certain animals treated with DMSO were found to have changes in the eye lens. Some of these changes resembled those seen in aging dogs (Gordon, 1967), but nevertheless, research was gradually restarted after no evidence was found of eye changes in humans. As Daniel Haley reports in his book Politics in Healing: “Tests in rabbits, dogs, and pigs (but not humans) had shown some problems. When quantities of DMSO equal to about ten times the maximum human dose were given every day over a period of six months, slight changes in the lenses of the animals’ eyes would result, enough to produce a slight nearsightedness. The lens changes were not enough to cause dogs difficulty when running – they didn’t bump into things – and in some cases, the changes disappeared after the massive DMSO doses were stopped. In no test at that time or since has DMSO ever caused cataracts, either in animals or in humans” (Haley, 2000).

In fact, DMSO is effective for macular degeneration and retinal disease, both diseases of the eye. This effectiveness was first discovered when patients with retinitis pigmentosa, a retinal disease, were taking DMSO for certain musculoskeleteal disorders. They sensed that their vision had improved and some had remarkable results (Morton, 1993).

As far as eyes are concerned, the evidence on DMSO is quite to the contrary. When several patients treated with DMSO for muscular problems reported to Dr. Jacob that their vision had improved, he sent them to Dr. Robert O. Hill, ophthalmologist at the University of Oregon Medical School. Confirming the favorable changes, Dr. Hill began his own experiments with DMSO (after it was known that the lens changes did not happen in humans). His research showed drops of 50% DMSO to be effective in retinitis pigmentosa and macular degeneration, and presented a report on this at the New York Academy of Sciences symposium in 1971. (Haley, 2000)

In contrast, the number of medication-related deaths in the U.S. is estimated at over 200,000 a year, making medications the third or fourth leading cause of death (Pezzalla, 2005). Even common pain relievers called NSAIDs, examples of which include Advil, Motrin, Aleve and aspirin, account for an estimated 7,600 deaths and 76,000 hospitalizations in the U.S. every year (Tamblyn et al, 1997). Taking this into consideration, it is safe to declare that DMSO is among the safest substances in the world today. In fact, the classic test for toxicity -the LD-50 test – measures the lethal dose (LD) at which half of a group of test animals is killed. The LD-50 tests for aspirin and DMSO show that aspirin is seven times more toxic than DMSO (Haley, 2000).

Quick Guide and Ailments

DMSO is generally applied to the skin in a gel, cream, or liquid. It can be taken by mouth or as an intravenous injection, in many cases along with other drugs. It has also been administered subcutaneously, intramuscularly, intraperitoneally, intrathecally, by inhalation, instilled into the eye, on the mucous membranes, and into the urinary bladder. Strenghs and dosages vary widely.
If you are just dealing with pain or an injury, use a topical application. Don’t drink it. Drinking it is for serious detoxing and other internal necessities. If you use a rose scented DMSO cream, chances are that nobody will be able to smell DMSO’s garlic-like smell.

DMSO being distilled.

 

The usual oral dose of DMSO is one teaspoon per day of DMSO 70% (Morton, 1993). But since it can trigger detoxification reactions and DMSO’s total excretion from the body can take several days, it is best to do it only once a week. Start with half a teaspoon of DMSO 50% and increase to a teaspoon of DMSO 70% only if any possible detoxification reaction is well tolerated.

When you use liquid DMSO in the skin, let it dry for over 20 to 30 minutes before wiping the rest out. The skin must be clean, dry, and unbroken for any topical use of DMSO. The face and the neck are more sensitive to DMSO and no higher concenrations than 50% should be applied there. Topical concentrations of DMSO should be kept below 70% in areas where there is a reduction of circulation. When 60 to 90% DMSO is applied to the skin, warmth, redness, itching, and somtimes local hives may occur. This usually disappears within a couple of hours and using natural aloe vera, gel or cream, will help counteract or prevent this effect. When 60 to 90% DMSO is applied to the palm on the hand, the skin may wrinkle and stay that way for several days.

“My brother put some DMSO gel (70% dmso, 30% aloe vera) on his shoulders and lower part of neck because he had muscle pain/soreness in that area, and it caused skin redness/irritation for a few hours, although it did diminish the muscle soreness as well…my grandma has rheumatoid arthritis that made her legs swell up and hurt continuously, and I had her apply the same DMSO gel, and after about 2-3 days of applying it once a day, the swelling was 90% gone, and I think within 4-5 days it was 100% gone, and she said the pain diminished as well.” – Michael Shatskiy, Los Angeles, California, United States

Chronic pain patients often have to apply the substance for 6 weeks before a change occurs, but many report relief to a degree that had not been able to obtain from any other source. In general, the greater the chronicity of the disorder, the longer the treatment with DMSO must be employed in order to achieve palliation (Steinberg , 1967).

Common health problems for which people will apply topical DMSO at home include acute musculoskeletal injuries and inflammations. The earlier DMSO is used, the more dramatic the result. A 70% concentration of DMSO mixed with water in volumes ranging from 8 to 12 ml, applied on and around the injury in a wide area at least three times daily, will have a healing affect in 4 out ot 5 people.

Arthritis, Sprains, Strains

It provides rapid amelioriation of pain and increased mobility and reduction of inflammation when used topically. You can see a positive response within 5 to 20 minutes and usually lasting for 4 to 6 hours. (Steinberg, 1967).

“Applying DMSO where it hurt to a six-year-old wasted from rheumatoid arthritis, in a half hour the child could move her shoulder and turn her head for the first time in two years. Persuaded to try walking, she managed a few steps and then burst into tears. “Why are you crying?” Dr Jacob asked her. “Because it doesn’t hurt anymore”, she replied. (Haley, 2000)

“My brother has arthritis of the spine. He is in pain and bedridden more than half the time. When he is treated with DMSO, he is able to lead a normal, active life… Just one application of this cheap, safe DMSO changed my brother from a grimacing patient into an active, pain-free man in exactly 30 minutes!” (Haley, 2000)

June Jones, once quarterback and later coach of the Atlanta Falcons pro-football team, had a bursitis calcification in his right shoulder. His career almost didn’t happen as he could hardly lift his arm, let alone throw a football. But he was aware of DMSO and had used DMSO for sprains, like thousands of others. He received a shot of DMSO in the shoulder and after using DMSO for 30 days straight, the calcification disappeared. (Haley, 2000)

Stroke

Given soon after a stroke, DMSO can dissolve the clot that causes the stroke, restoring circulation and avoiding paralysis. Once DMSO gets into the body either daubed on the skin, given in I.V., or by mouth, it permeates the body and crosses the brain barrier, so even taken orally it can improve circulation. Ideally it should be I.V.

DMSO products

DMSO is available in various formats.

 

Even though DMSO 40% causes a prolongation of bleeding time, it is still indicated for use in treating embolic or hemorrhagic stroke. DMSO is superior to any other treatment for wounds to the brain where a great deal of bleeding is present (Morton, 1993).

One man who had a stroke at 7:30 AM refused to go to the hospital until after his wife had spoken with Dr. Stanley Jacob, which didn’t happen until 6:30 PM. Starting at 7 PM the day of the stroke, she gave him one ounce of 50% DMSO in a little orange juice every 15 minutes for two hours and then every half hour for two hours. The next day, her husband was better and soon returned to normal. A substance that can stop a stroke as it’s happening is something many might want in their home medicine chest .(Haley, 2000)

Angina, Heart Attacks, Injuries of the Brain and Spinal Chord

DMSO may help neutralize harmful effects on the heart and brain in medical disorders involving the head and spinal chord injury, stroke, memory dysfunction, and ischemic heart disease (Jacob, de la Torre, 2009). A 40% DMSO solution should be administered within four hours to be effective, within ninety minutes is best.

After I.V. administration of DMSO, there is an elevation in the amount of spinal cord blood flow to the region of trauma. One of the first things that happens after spinal cord trauma is that a reduction of oxygen and blood flow sets in, inasmuch as the blood vessels constrict or shut down… Without some treatment, the tissue swells. Eventually, this leads to paralysis. In a cerebral stroke, the animal will either become comatose or lethargic or die. With DMSO infusion immediately after injury (or stroke) all this is prevented. – Dr. Jack de Ia Torre, professor of physiology and neurosurgery at the University of New Mexico

Dr. Stanley Jacob has even given DMSO intravenously to people who were already paralyzed – paraplegics – and some regained use of limbs. One man, quadraplegic, recovered enough to go through college and then to work in a bank. (Haley, 2000)

Infections

When combined with antibiotics, DMSO will convert bacteria which are resistant to a given antibiotic to being sensitive to that same antibiotic and probably a 80 to 90 per cent solution of DMSO will be required in order to be clinically useful ( Pottz, Rampey, Benjamin,1967). DMSO has been used to transport antibiotics to hard-to-reach areas of the body with excellent results, such as the bone marrow and brain (Sanders, 1967).

DMSO can dissolve a virus protein coating, leaving the virus core unprotected with its nucleic acid exposed to the immune system. Applied topically, it alleviates the lesions that occur as a result of Herpes Zoster, shingles (Morton, 1993).
Placed into the nostrils or topically in the face, DMSO can open blocked sinuses within a few minutes and it has been used with sucess in patients with polyps (Marvin, 1967).

DMSO can clear up gum disease and reduce tooth decay and their pain by painting it on the involved areas.

“I have some pharmaceutical grade DMSO and I pour about two teaspoons in a glass in the evening, put my 20 mg of doxycycline in it, add about 2 teaspoons of distilled water, and then swish it around in my mouth for about 2 or 3 minutes and then swallow it. So I guess it is about 50% solution. It’s really working on my mouth. That inflamed area of my jaw has calmed down about 70% in just a couple of days. Or more, actually. I expect it to be completely soothed by tomorrow after tonight’s dose of DMSO.” – Laura, Toulouse, France

Keloids, Scars, Burns, Bruises

A concentration of 50 to 80% put on two or three times a day will flatten a raised scar after several months. It is of considerable value in superficial burns (Goldman, 1967) and when applied quickly to an injury, it can eliminate any bruising.

“I have been applying it to my face for two weeks… I had a bout of acne in March, and this healed the damage pretty well but what amazed me is that my hyperpigmentation (melasma) has also faded very noticeably. In fact, it’s amazing!” – HG, United States

“I diluted a 50% solution and applied it topically to the inflamed lymph node. I applied it again this evening. I am totally amazed! There is a noticeable decrease in the size of the node, in just two applications! And it no longer feels matted. This node has been swollen for over 20 years!!! – Melissa Medlock, Coldwater, Michigan, USA

Podiatry

DMSO can be effective in the treatment of painful corns, calluses, ingrown toenails, bunions, hammertoes, heel spurs, and the inflammation of gouty big toes.

Varicose veins and thrombophlebitis

Topical DMSO can whiten telangiectasias, small dilated blood vessels near the surface of the skin. It can also decrease the size of varicosities in the legs and the inflammation that goes with it, along with a relief of their cramping discomfort (Marvin, 1967. Blumenthal, Fuchs, 1967).

Eye problems

One drop of a 25% DMSO solution (diluted in sterile physiologic or saline solution) once or twice per day is useful for eye problems, including cataracts or glaucoma.

“DMSO is amazing, I’ve also read various good results with using it in the eyes. Being the adventurous type myself, today I diluted DMSO down to 30% and put 2 drops in one of my eyes that has been having red spots around the iris. The red spots diminished drastically. The only side effect was a slight burning sensation, similar to those drops you get when one goes for a glaucoma test, without the side effect of dilated pupils.” – DZ, United States

Headaches

DMSO is highly effective in vascular headaches and in muscular tension which so often goes with headaches. It may be used on hairy areas such as the scalp and it also may be used near the eyes. A 90% solution is more effective (Ogden, 1967).

Mental Disorders

DMSO has been useful in the treatment of patients with the following diagnoses: (1) overexcited states (acute schizophrenic reactions, manic phase of the manic-depressive psychoses, alcoholic psychoses, symptomatic psychoses); (2) some symptoms of the chronic psychoses (autism, stereotypia, negativism, abnormal behavior or delusional states) ; (3) severe neuroses (anxiety reactions, obsessives)( Ramírez, Luza, 1967).

McGrady called special attention to an extraordinary paper presented by Dr. Eduardo Ramirez and Dr. Segisfredo Luza of the Ayetano Heredia University in Lima, Peru. After extensive tests on animals and then on normal humans, Dr. Ramirez reported “injecting 50% or 80% DMSO intramuscularly into patients with acute and chronic schizophrenia” and that “of the 14 acute cases, every single one was discharged from the hospital within 45 days after the start of DMSO treatment… He said that 4 of the 11 chronic cases, one of whom has been ill for 14 years, were discharged eventually, and the other 7 improved a great deal and were given occupational therapy… He observed rapid decrease in agitation… recession of persecution feeling, a relatively sudden tendency to communicate and to stay clean.., the wane of obsessions, return to alertness, and a calmness where there had been restlessness and anxiety”. (Haley, 2000)

Genitourinary disorders

DMSO has been used in the treatment of a number of patients with various genitourinary disorders, including Peyronie’s disease, interstitial cystitis, acute epididymitis. Some have obtained dramatic and gratifying relief of symptoms (Persky, Steeart, 1967).

Miscellaneous

DMSO in conjunction with other treatments has shown to regress cancer in a very effective way (Ayre, 1967). Intravenous administration of DMSO markedly reduces pathological intestinal permeability while preserving the gut’s absorption capacities (Wang et al, 1996). Considering that gut permeability (‘leaky gut’) has a fundamental role in chronic degenerative diseases, this is of great clinical importance.

DMSO also has excellent results in the skin of people afflicted with scleroderma, results which have never been observed with any other method of therapy (Scherbel et al, 1967).

Mrs. Jean Puccio of Washington, DC testified at hearings of Senator Edward Kennedy’s sub-committee on health in 1980 on her recovery from scleroderma. Diagnosed in 1971, she was told that no medication would help, and that she would probably soon face a wheelchair and early death. By the time she found Dr. Jacob (through word of mouth), she told the Senators, “I was having difficulty breathing, walking, and eating”. The disease “thickens the tissue and makes your skin so tight you cannot move. It was difficult for me to drive, to turn the ignition in my car or turn my body”. Her dentist could not work on her for awhile because she could not open her mouth. “Now I can open my mouth like anybody”, she said. After her sensitized skin burned from topical application of DMSO, Dr. Jacob suggested taking it orally. “Within six months”, she testified, “my condition reversed almost immediately. I can do anything anybody else can do now” (Haley, 2000).

Hopefully, this brief overview of DMSO’s great capabilities has helped to illustrate how it is indeed, the cure of our times. I’m convinced of its therapeutic power, both by my own experience and that one of scores of people, not to mention the back-up of published scientific literature. Its uses and applications make it a very handy compound to have on your medical shelf. In pure form, the life of DMSO is indefinite, so it may be used for years.

 

Several books have been published on the benefits of DMSO.

 

Troubleshooting

The garlic-like body odor and taste in the mouth that some experience is attributable to a specific DMSO metabolite: dimethyl sulfide (DMS), a component of natural onion and garlic flavors (McKim, Strub, 2008). This can last for one or two days and in a small number of people, especially men, the odor can be very pungent. Drinking enough water will help diffuse the smell. Other side effects – such as stomach upset, headaches, dizziness, and sedation – are very likely related to detoxification reactions prompted by the DMSO.

Only purified and properly diluted DMSO should be used. When you dilute a pure DMSO solution, always do it in distilled water. When it is applied, the skin site as well as the applying hand should be thoroughly cleaned before application. This is of utmost importance as DMSO’s properties allow contaminants to be absorbed through the skin and transported into the bloodstream.
DMSO is known to be one of the least toxic substances in biology (Parcell, 2002), so any serious side effects should come from potential contaminants or the intake of concomintant drugs that DMSO will carry into the body. Worth repeating again, DMSO and any substance dissolved in it, will penetrate the skin, the blood-brain barrier, and other parts of the body very fast.

Remember also that DMSO increases the effects of drugs like blood thinners, steroids, heart medicines, sedatives, etc. In addition to that, acetone or acid contamination of DMSO can lead to serious medical consequences. Be aware of this problem when buying unreliable DMSO. A pure DMSO solution will turn solid (like ice) in the refigerator within 2 hours. If, when the frozen bottle is turned upside down, little rivulets of water flow through the ice, you probably possess the veterinary grade DMSO. This is a 90% concentration. Ten percent is distilled water (Morton, 1993).

Women are discouraged from using DMSO during pregnancy or breastfeeding, even though DMSO is used to preserve frozen human embryos. DMSO can interfere with liver function tests and give a false reading. That problem is easily solved by waiting a week after DMSO usage before taking the test.

Long-term use has been documented as safe. Eye damage, reported in laboratory animals, has not been confirmed. Side effects such as skin rash and itching after topical application, breaking up of blood elements after intravenous infusion, can be avoided in large part by employing more dilute solutions. Despite these side effects, DMSO is used as a preservative for blood elements and stem cells (McKim, Strub, 2008).

When DMSO is diluted with water, heat is released. The bottle will be warm to the touch. This is a temporary, harmless reaction.
Since DMSO causes dryness and scaling of the outer layer of the skin, skin diseases characterized by scaling (psoriasis) could be aggravated by the use of DMSO. But DMSO applied topically for only a few days has been useful in psoriasis. Prolonged use of DMSO for the treatment of psoriasis is not advised however, as it can worsen the psoriatic condition (Engel, 1967), only DMSO taken orally is suggested.

“I’m happy to say that taking DMSO in conjunction with implementing the detoxification suggestions that were given is starting to take care of many of my remaining psoriasis problems. A couple areas are still being stubborn, but I’ve noticed a lot of general improvement. Using DMSO topically also helped improve a patch of eczema that my wife has been bothered by for quite a while.” – Peter Norquest, Tucson, Arizona, United States

DMSO2, a derivative of DMSO, is better tolerated and doesn’t have the odor and irritation side effects. Despite this positive aspect, it hasn’t surpassed the effectiveness, fascination and popularity of DMSO. It is also known as methylsufonlmethane or MSM, an entire topic for another article by itself!

Sulfur is an element of the earth and it is essential to life, it as among the most prevalent elemenents in the human body. Allergic reactions to sulfur are not possible because sulfur has no protein component. When people are ‘allergic to sulfur’, what they really mean is that they are allergic or sensitive mainly to certain sulfur-containing drugs or proteins, most notably sulfa antibiotics (sulfonamides) or to sulfites (preservatives used in wines and some foods), or to foods with a high sulfur content (broccoli, cauliflower, garlic, onions, etc). Many individuals with allergies to sulfa drugs, sulfites, or high sulfur containing foods (like the author) do not experience problems taking DMSO, because apart from sulfur, DMSO bears no relation to these substances.

As always, proceed with caution, do your homework, and consult a health care provider in case of doubts.

References

Ayre JE, LeGuerrier J. Some (regressive) effects of DMSO dexamethasone upon cervical cells in cervical dysplasia and carcinoma in situ. Ann N Y Acad Sci. 1967 Mar 15;141(1):414-22.
Blumenthal LS, Fuchs M. The clinical use of dimethyl sulfoxide on various headaches, musculoskeletal, and other general medical disorders. Ann N Y Acad Sci. 1967 Mar 15;141(1):572-85.
Engel MF. Indications and contraindications for the use of DMSO in clinical dermatology. Ann N Y Acad Sci. 1967 Mar 15;141(1):638-45.
Goldman J. A brief resume of clinical observations in the treatment of superficial burns, trigeminal neuralgia, acute bursitis, and acute musculo-skeletal trauma with dimethyl sulfoxide. Ann N Y Acad Sci. 1967 Mar 15;141(1):653-4.
Gordon DM. Dimethyl sulfoxide in ophthalmology, with especial reference to possible toxic effects. Ann N Y Acad Sci. 1967 Mar 15;141(1):392-401.
Haley Daniel. Politics in Healing. Potomac Valley Press, 2000.
Jacob SW, de la Torre JC. Pharmacology of dimethyl sulfoxide in cardiac and CNS damage. Pharmacol Rep. 2009 Mar-Apr;61(2):225-35.
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Pottz GE, Rampey JH, Benjamin F.Ann- The effect of dimethyl sulfoxide (DMSO) on antibiotic sensitivity of a group of medically important microorganisms: preliminary report. Ann N Y Acad Sci. 1967 Mar 15;141(1):261-72.
Ramírez E, Luza S. Dimethyl sulfoxide in the treatment of mental patients. Ann N Y Acad Sci. 1967 Mar 15;141(1):655-67.
Sams WM Jr. The effects of dimethyl sulfoxide on nerve conduction. Ann N Y Acad Sci. 1967 Mar 15;141(1):242-7.
Sanders M. Discussion. Annals of the New York Academy of Sciences. Volume 141, Biological Actions of Dimethyl Sulfoxide pages 649 – 652, March 1967.
Scherbel AL, McCormack LJ, Layle JK. Further observations on the effect of dimethyl sulfoxide in patients with generalized scleroderma. (Progressive systemic sclerosis). Ann N Y Acad Sci. 1967 Mar 15;141(1):613-29.
Steinberg A. The employment of dimethyl sulfoxide as an antiinflammatory agent and steroid-transporter in diversified clinical diseases. Ann N Y Acad Sci. 1967 Mar 15;141(1):532-50.
Tamblyn R, Berkson L, Dauphinee WD, Gayton D, Grad R, Huang A, Isaac L, McLeod P, Snell L. Unnecessary prescribing of NSAIDs and the management of NSAID-related gastropathy in medical practice. Ann Intern Med. 1997 Sep 15;127(6):429-38.
Walker Morton. DMSO Nature’s Healer. New York: Avery, 1993.
Wang XD, Wang Q, Andersson R, Ihse I. Alterations in intestinal function in acute pancreatitis in an experimental model. Br J Surg. 1996 Nov;83(11):1537-43.

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Comments

  1. wong  April 24, 2013

    Hi Gabriela,
    Can i take dmso orally to disovle/clear blockage in the small intestine? If yes, what should be the dose?
    Thanks.

    reply
    • Gabriela Segura, MD  April 26, 2013

      I would take no more than half a teaspoon as a test, making sure to drink enough water. One must be careful with oral DMSO as it can have different effects on different people according to their toxic load and individuality. Make sure to contact a health care provider if the problem persists.

      reply
  2. Uriel  April 27, 2013

    Hello,

    I have a slight tear in my patella tendon. How often should I apply DMSO gel to it?

    Thanks,

    Uriel

    reply
    • Gabriela Segura, MD  April 28, 2013

      I would apply it twice or three times per day. Speedy recovery!

      reply
      • Uriel  April 29, 2013

        Thanks for the reply!

        I look forward to seeing how it works.

        And great article!!

        Uriel

      • Gabriela Segura, MD  May 2, 2013

        I hope it helps you! The earlier you apply DMSO the better. It is one thing to have on your medical cabinet, that is for sure!

  3. Tina  May 5, 2013

    Hi,

    I have worst case of melasma on face. Could DMSO help me with that. If yes, than at what concentration orally/externally?

    Thanks

    reply
    • Gabriela Segura, MD  May 12, 2013

      As a test, I would try the DMSO rose cream version, which is 50%. It is very mild on the skin.

      reply
  4. Katrina  May 15, 2013

    I have a 90% liquid DMSO. Is there a way for me to add something to get it to a different percentage for various uses?

    reply
    • Gabriela Segura, MD  May 15, 2013

      Sure Katrina, you just add filtered water or physiological solution depending on diluted you want it to be. You can calculate this roughly.

      reply
      • Brig Brown  May 20, 2013

        Dear Gabriela,
        First of all, I’d like to thank you for your unconditional support and education especially on DMSO.
        As I had mentioned in some of my prior emails, I suffered from chronic fatigue and rheumatic arthritis, which had caused me to live in constant pain. Often the pain was so dominant in my life, that I felt depressed and deprived. None of that is promoting an active lifestyle.
        After learning about DMSO, I researched everything I could and finally purchased a bottle with 99.9% DMSO, which I diluted 50% with distilled water. I sterilized a brown glass bottle and a glass spray bottle to be available for daily use. Then, before walking my dog in the mornings, I sprayed the solution onto the most areas I experienced most pain. I instantly felt relief and continued using the spray. About a week after, I started taking orally a tablespoon of the solution with juice every morning (21 days now). I am mostly pain free now. Next month I am creating a 70% solution to take orally. I feel my overall health has much improved.
        Since then, I also used the solution to treat a nasty corn I had between my toes. The corn stopped developing as usually, and the pain when walking is gone or tolerable. I don’t experience much of the garlic taste though.
        My newest approach was to use DMSO in my household. I live in an area where ticks are a huge problem, and I find up to 10 of these pesty creatures every day. I am mortified of ticks!!
        So, I dropped the ticks I found into a small glass with DMSO, and what do you know, they died instantly. I am ordering a larger amount to treat my floors, hoping they will stay away from my home.
        Oh, one more experience I have to share; when I cut myself, I treated my finger with tripple antibiotic cream, sprayed DMSO solution onto the area, and place a bandage on top of it. The next day, I could hardly see where the cut was.
        I will keep you updated on my experiences, and appreciate all of your feedback.
        Gratefully
        Brig Brown

  5. Gabriela Segura, MD  May 21, 2013

    Dear Brig Brown,

    Thank you very much for sharing, that is a fascinating experience. I’m also most interested in the tick problematic. Let me know how it goes. Tick-borne diseases are extremely problematic and if DMSO will help get rid of ticks when you treat the floors, I’m sure a lot of folks will love to hear about that. I’m so glad to hear about your health progress. Cheers!

    reply
    • Brig Brown  June 12, 2013

      Dear Gabriela,
      This is an update on my experiences fighting ticks with DMSO.
      I started treating the floors in the entrance of the house with 90% commercial DMSO and sprayed my dog’s legs and coat with a 50% solution prior to walking. I have not found a tick alive in the house for the past 2 weeks. Though I did find several dead ticks around the house.
      Much gratitude for you and your work
      Brig

      reply
  6. Gilly  May 26, 2013

    Hi
    I have an inflammatory breast cancer with a local occurrence on the skin of my upper body, would DMSO be useful, if so what dose and frequency should I use it

    reply
  7. rufus  June 11, 2013

    Can dmso be used as a carrier of dextrose instead of injections? (Ref: Prolotherapy treatment for pain and inflammation)

    reply
    • Gabriela Segura, MD  June 12, 2013

      As a general rule, I wouldn’t mix anything with DMSO that I don’t want in my brain. Just to give you a general idea. If the dextrose is sterile, shouldn’t be much different than many experiments already done with DMSO. Best!

      reply
  8. yerry pl  June 23, 2013

    Witaj Gabriela,
    dzięki za świetny, bogaty w wartościowe treści artykuł. Dowiedziałem się z niego o wielu nieznanych mi dotychczas praktycznych możliwościach prozdrowotnego zastosowaniach siarki organicznej w postaci DMSO.

    Pozdrawiam Ciebie i komentujących!
    yerry pl.

    reply
  9. larry  June 29, 2013

    Hi Gabriela Segura, MD
    Thank you for the best article I have read on this subject.

    Quick question please.

    How do we (the people) find out how to manufacture this DMSO.

    It may end up being banned by corrupt politicians via some kind of scandal and it would be nice IF the public knew how to make this themselves.

    I for one have suffered with migraines all my life, which are exacerbated by chemicals, especially those fed to cows, sheep, chickens etc and would like to give my kidneys and liver a break from pain killer tablets.

    Thank you most kindly in advance
    Larry

    reply
  10. Gabriela Segura, MD  June 30, 2013

    Dear Larry,

    I’m glad you found the article useful. I personally don’t know how to manufacture DMSO, but perhaps you can find out within the wood industry itself. See: http://en.wikipedia.org/wiki/Kraft_pulping and http://en.wikipedia.org/wiki/Dimethyl_sulfoxide for a pic on the distilling process.

    I hope your migrains get better. I would like to recommend you Primal Body Primal Mind by Nora Gedgaudas for some great health tips.

    All the best!

    reply
    • Larry  June 30, 2013

      Hi Doc
      I found the information so good that I had to stop myself from complimenting you too much in case you thought I was proposing :)

      It was absolutely brilliant on many levels.

      It is sooooo difficult to get excellent articulate quantitative information these days which is not tainted by big pharma propaganda. I was almost in shock.

      I will research further about manufacture but so far I have not come up with anything to my liking.

      BTW
      This is just my 2 cents but wikipedia is more of a dis-information website that an informed one.

      I have personally been involved with certain military and other adventures and have tried to correct misinformation on their website and was banned once even when I provided links to verify my claims and pointed out that the info they had was factually and historically wrong. I also know several other people listed in wikipedia where others have posted information about them which is completely false and when they have tried to correct these mistakes, they have been dismissed even after supplying an email address and contact details via their verifiable website.

      On top of that, IF you read about Royal Raymond RIFE, Harry Hoxsey, or Elle Caisse, or even DMSO for that matter, you will find limited information to the point of un-researched and un-substantiated actual lies. I can go on for a week about that website before drawing breath, but I hope you get my drift.

      Anyway, thank you.

      reply
      • Gabriela Segura, MD  June 30, 2013

        So true Larry, I have heard and experienced past censorship regarding wikipedia. At least you can see how the distilling process looks like and where you can find more information regarding its extraction. The world is full of disinformation and doing your own homework is the only way to go. I love doing research and hearing everybody’s experience regarding their health quest. I hope to write up more of what has proved to be effective for a lot of folks out there.

        Let me know if you find a way to manufacture DMSO in a safe way. Don’t lose hope and keep on going. The best gift each one of us can give.

        Best!

      • Larry  July 1, 2013

        BTW Doc, I forgot to suggest that there may be a way of getting around the double blind test.

        Rub some “liquid” on both groups and then give both groups a strong Garlic lozenger so that it disguises the taste for both groups. (not tablet)

        This would get around the garlic taste.

        what do you think.

        Clever for a boy or what ?

        regards

      • Gabriela Segura, MD  July 2, 2013

        That is very ingenous!! I will just make sure that both groups don’t know how DMSO smells just in case they can recognize the fake one vs the non fake one. Best!

  11. Michael  August 22, 2013

    Hello Dr Segura,

    You seem prefer DMSO to MSM. Is it more safe or effective ? Can you explain why ?
    Thanks

    reply
    • Gabriela Segura, MD  August 22, 2013

      I prefer DMSO because it is pretty effective in acute phases. For detox purposes and such, I would understand if one or the other is used. But when you have something that relieves pain so effectively, then it grows on you. MSM is safer as side effects, or so it seems.

      reply
  12. Carolyn  August 28, 2013

    Hi,

    I have a few queries…

    1) where do you buy DMSO?

    2) My daughter has got a pilonidal cyst; can this be used and how?

    3) I suffer from asthma, can I use it and how?

    Thx for all this sharing.

    reply
    • Gabriela Segura, MD  August 29, 2013

      Hello Carolyn, for open wounds or inflammation of that kind (pilonidal cyst9, I would get the DMSO rose cream version, for instance on amazon: http://www.amazon.com/DMSO-Cream-Rose-Scented/dp/B000ZCVVI8

      jacoblab.com has pharmaceutical grade DMSO.

      For asthma, it would be dietary changes that will give you the most results. For more information see “Primal Body, Primal Mind” by Nora Gedgaudas. Most people improve when they remove dairy and gluten products from their diet. It never fails! Best!

      reply
  13. Larry  August 28, 2013

    Gabriela Segura, MD

    Hi Doc
    As you know, I am a DMSO fan, (and yours of course) however I would like to point out that the picture you have on your website of the WHITE BOTTLE of DMSO has NO safety info, NO MSDS info, barely a company name, NO Company contact details,clearly states that this product is NOT APPROVED for Human use.

    You can buy a bottle of this from Amazon.com and see what I am saying.

    http://www.health-matrix.net/2011/03/15/dmso-the-real-miracle-solution/

    People see this bottle on your website and assume subconsciously that it is safe because you “appear” to be endorsing it.

    ALSO
    I would like ur permission to re-run your last DMSO email // at least 4 paragraphs with a link back to your website for the full story.

    I have only started this 2 months ago and only have a few hundred subscribers.

    Something like I submitted here on my FB page
    https://www.facebook.com/preppers.newsletter

    Thank You
    Larry K

    reply
    • Gabriela Segura, MD  August 29, 2013

      Sure Larry K, go ahead.

      DMSO will always have all kinds of warnings written all over it due to the controversy surrounding it. I would much rather see those kinds of warnings in dangerous pharmaceuticals that people think are safe because they are endorsed by the FDA.

      reply
  14. Denise  August 29, 2013

    Hello…I really enjoyed your article! Thanks.
    I have a dear friend who is suffering with Lou Gehrig’s disease.
    Would DMSO be of help to her in any way? Or…do you have any
    other suggestions of alternative treatments for Lou Gehrig’s?

    Thanks so much.
    Denise

    reply
    • Gabriela Segura, MD  August 30, 2013

      Hello Denise! DMSO would help, I would focus on dietary changes which make all the difference. You can read this review to see the benefit potentials:

      The Ketogenic Diet – An Overview
      http://www.health-matrix.net/2013/08/09/the-ketogenic-diet-an-overview/

      I would get a copy of “Primal Body Primal Mind” by Nora Gedgaudas. It not only summarizes all the scientific points, but shares her experience as a specialist in neurofeedback and how alternative therapies helped her and her patients. It is one of the best books out there for its quality content and tips that really make the difference.

      Mark Sisson’s “Primal BluePrint” gives specifics guidelines on how to transition from a Western diet into an anti-inflammatory diet.

      I hope this helps.

      reply
  15. Ola Eklund  September 2, 2013

    Hi,

    I have an invisible crack which hurts inside one teeth that goes down to the root of the tooth. I have also under the same tooth problems with the jawbone which is probably an infection according to the dentist.
    Because of that infection I have removed one tooth and and will have to remove more teeth. If I lose that tooth and other I will lose the ability to eat at my right side.
    To save that situation my idea is to use DMSO and Colloidal silver combined and to keep it in the mouth 20 min twice daily. The problem is that I have removed all the amalgam fillings but there is a dark shade inside some of the teeth and the dentist is assuming, but is not sure, that the teeth could have absorbed some of the amalgam. The question is if the dmso could get in contact with that amalgam and carry it inside the body? Should I use dmso in this case? Also, is it possible in this way to heal the jawbone and the tooth?
    I look forward to your opinion.

    Kind regards,
    Ola Eklund

    reply
    • Larry  September 2, 2013

      Here is something your dentist will never tell you.

      Recaldent.

      Recaldent occurs naturally in RAW UNPROCESSED milk and will naturally heal the cracks in your teeth ( I am living proof that this is true ) I dived into the bath tub when I was about 8 yrs old and cracked the 2 top front teeth. These cracks have completely gone by the times I was 16 and working on a farm.

      DO NOT buy commercial Recaldent as almost all of this stuff comes from toxic polluted farms in China. (why ? I do not know)

      You may like to try this, mix a quarter teaspoon of Coral Calcium (www.coralcalcium.com) with 2 pints (1 liter) of RAW Unprocessed cows milk and drink. Swish around in your mouth for a few seconds if you like (optional)

      You will see the cracks disappear within a few months. Try and get A2 milk if possible as well (harder to do but worth it)

      Good Luck.

      reply
      • Gabriela Segura, MD  September 2, 2013

        Mouth washes with DMSO and comfrey root are good for healing the bone. I don’t trust dairy products for any of these issues for reasons I wrote here:

        Why Milk Is So Evil
        http://www.health-matrix.net/2010/06/05/why-milk-is-so-evil/

        But have seen and heard great testimonials doing mouthwashes with DMSO and comfrey root. Note, it doesn’t have to be consumed. It is just for local use where the problem is located. In case of doubt, you can apply comfrey root directly and alone where the problem is located. Cheers!

  16. evolver  September 7, 2013

    I am wanting to target heavy metal detox from the brain and other deep neurological areas, and also fluoride detox from the endocrine system. Is there any chemical reason why DMSO should not be used in conjunction with Lugol’s solution (Iodine & Iodide) and/or Borax? Would you say it would help target detox frrom these deep lying tissues? Any suggestions for oral dosing for greatest efficacy?

    Many thanks…

    reply
    • Gabriela Segura, MD  September 7, 2013

      Hello evolver,

      I would not combine both for ingestion, as it doesn’t sound safe. I have done a heavy metal detox and it took me nearly a year to prepare it, mainly healing the gut which is a requisite so to speak. Also doing far infrared saunas. I used the DMSA protocol explained at the Autism Research Institute and in the last cycles, I included some DSMO along with my DMSA, but not mixed together. I took them separately. It was an experiment and it did create withdrawal symptoms with later improvement. Nevertheless, I would not recommend mixing those substances as it doesn’t sound safe. The heavy metal detox was researched at sott.net discussion forum. Here is the gist of it FWIW:

      http://www.huffingtonpost.com/dr-mark-hyman/autism-mercury-toxicity_b_497047.html

      Best!

      reply
  17. Ola  September 7, 2013

    Hi,
    Is it okay to mix DMSO and colloidal silver, to be used for eye problems?

    Thank You,
    Ola

    reply
  18. Carol  September 11, 2013

    I purchased a bottle of MSM + DMSO 10X solution. It says use only if solution is clear. My bottle has not been opened, it was exposed to sunlight on my drive home, but not heat, I had the ac on. Is it ok to use?

    reply
  19. Gabriela Segura, MD  September 11, 2013

    It should be okay. You can check on its purity by putting it on the fridge. It will turn like a block of ice. Getting it back to liquid form can be tricky though. In any case, from the way you describe it, it should be safe.

    reply
  20. Ola  September 11, 2013

    Hi,
    I have read in Dr. Mortons book that DMSO mixed with SOD(sodium oxide dismutase) is the most effective way to get rid of cataract. Where can I purchase SOD without ingredients that could be dangerous in combination with DMSO?

    Thank You,
    Ola

    reply
    • Gabriela Segura, MD  September 12, 2013

      Hi Ola,

      I honestly don’t know, but you can start at your local pharmacy to see if they have a supply. When sold as eye drops, it should be safe enough. Best!

      reply
  21. David  October 13, 2013

    Oh… Lets have fun. I have giardia/ candida/ leaky gut… Liver issues… The whole 9 thAt goes hand and hand with parasites… Whats a warrior type protocall in ur opinion. A super stack soto speak!! Any articles or forums to check. Thx sooo sooo much for ur work.

    reply
    • Gabriela Segura, MD  October 13, 2013

      Hey David, might want to check out this protocol _http://www.markusrothkranz.com/bodyforce/parasite.html Not for the products per se necessarily, but the ingredients. I don’t think DMSO alone will do it.

      reply
      • evolver  October 14, 2013

        Highly recommend you research borax powder for parasites… incredibly effective against candida too… just start slowly as the candida die off reactions can be pretty major (herxheimer reaction)

      • Connie  July 21, 2018

        diataemeous earth food grade gets rid of parasites. research great for many things,

  22. GB  December 1, 2013

    I have glaucoma and cataracts. I am pretty healthy otherwise and do not take any medicines besides eye drops for my glaucoma. I read there are eye drops for cataracts and glaucoma that include DMSO, glutathione and Vitamin C. I noticed you have a recipe with just DMSO. What proportions of Vitamin C and glutathione would I include in the formula besides the 30% DMSO? Thank you.

    reply
  23. GB  December 1, 2013

    P.S. The eye drops are originally from Dr. Robert Rowen but there are no proportions given.
    Thanks.

    reply
    • Gabriela Segura, MD  December 1, 2013

      You can contact the lab to find out. At least they can provide some studies from which they based their formula to have an idea of the doses. Best!

      reply
  24. Kwabena  December 18, 2013

    Hi, Will DMSO cream/liquid help 10 year old Keloids ?

    reply
    • Gabriela Segura, MD  December 18, 2013

      It should help, Kwabena. I would read the article carefully to keep perspective on DMSO’s properties and effects. Often, long use is necessary to see some results in this one. Sometimes, warts and the like fall off. With keloids, it is more difficult due to the nature of the scar tissue.

      reply
  25. Robert  December 25, 2013

    Hi,

    i have cat with cancer. Can I use DMSO for this cat? I give the cat a bath with MMS and I want there to add the DMSO. It would not hurt her?

    Please help me.

    Thanks a lot.

    reply

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