DMSO: The Real Miracle Solution

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Due to the nuclear alert in Japan and its likelihood to affect the United States and other parts of the world, I decided to carry this article which I wrote for the Dot Connector Magazine‘s issue N. 12.

First, a little bit of background.

Radiation produces free-radicals (“inflammatory molecules”) that damage cells that make up tissues such as organs, glands, muscles, and bones. Besides causing the cells to age more quickly they also become distorted, or mutated, creating cancers such as leukemia, anemia, birth defects, and other diseases.

Sulfur has a long history of use as an antidote for acute exposure to radioactive material. DMSO is the classical sulfur compound. A Japanese study showed that even low concentrations of DMSO had radio-protective effects through the facilitation of DNA double-strand break repair, providing protection against radiation damage at all cellular levels in the whole body.

Remember that boosting your body’s detox capabilities and overall anti-oxidants levels is a key to survive in these stressful times. Being on a detox diet is crucial to regain health in a toxic environment. Our extensive experience and research shows that those on a no grain/low carb (no gluten) and non dairy diet fare MUCH better.

For more information on how to protect yourself from nuclear radiation, see:

Treatments for Nuclear Contamination

Iodine Treatments for Radiation Exposure – Radioprotective

DMSO is an effective pain killer, blocking nerve conduction fibers that produce pain. It reduces inflammation and swelling by reducing inflammatory chemicals. It improves blood supply to an area of injury by dilating blood vessels and increasing delivery of oxygen and by reducing blood platelet stickiness. It stimulates healing, which is a key to its usefulness in any condition. It is among the most potent free radical scavengers known to man, if not the most potent one.

In 1866, Russian scientist Alexander Saytzeff isolated a most curious and peculiar chemical compound. It was crystalline, odor-less, non-toxic and had a garlic-like taste when consumed. At the time, Saytzeff had no way to predict that his discovery was going to prove highly controversial throughout its entire medical history, that it was going to be tested in thousands of studies, providing miraculous relief in numerous patients.

I’m talking here about dimethyl sulfoxide (DMSO), an organic sulfur compound which was used only as an industrial solvent, that is, until its medical properties were discovered in 1963 by a research team headed by Stanley W. Jacob, MD.
DMSO is a by-product of kraft pulping (the “sulfate process”) which converts wood into wood pulp consisting of almost pure cellulose fibers. As industrial as it may sound, the process simply entails a treatment of wood chips with a mixture of sodium hydroxide and sodium sulfide, known as white liquor, breaking the bonds which link lignin (from the Latin word lignum, meaning wood) to the cellulose.

DMSO is useful as a pain reliever, in burns, acne, arthritis, mental retardation, strokes, amyloidosis, head injury, scleroderma, it soothes toothaches, eases headaches, hemorroids, muscle strains, it prevents paralysis from spinal-chord injuries, it softens scar tissues. In fact, it is useful in well over 300 ailments and it is safe to use. You would think that a compound that has so many alleged uses and benefits will be automatically suspect, but careful examination of its properties and the data available will shed some light in this miraculous chemical.

Sulfur: The Stuff of Life

DMSO is an intermediate product of the global Sulfur Cycle which distributes bioavailable sulfur for all animal and plant life (Parcell, 2002). Sulfur compounds are found in all body cells and are indispensable for life, they are needed for a number of chemical reactions involved in the detoxification of drugs and other harmful toxins, and they have potential clinical applications in the treatment of a number of conditions such as depression, fibromyalgia, arthritis, intersticial cystitis, athletic injuries, congestive heart failure, diabetes, cancer, and AIDS (Parcell, 2002). Among the sulfur compounds, DMSO is probably the one that has the widest range and greatest number of therapeutic applications ever shown for any other single chemical. It has around 40 pharmacological properties that may be beneficial in the prevention, relief or reversal of numerous diseases (Morton, 1993).

Someone complained to Dr. Jacob of a splitting headache and gave him permission to apply some DMSO after hearing of its capabilities. The headache was gone in minutes, came back in four hours, and left for good after DMSO was applied a second time. Used for one purpose, sometimes it did another; put on a cold sore, within a few hours it cleared up a woman’s sinusitis. A woman who had had a stroke found after DMSO was painted on her painful jaw that she could now write with her paralyzed hand and could walk better. (Haley, 2000)

Therapeutic Properties

DMSO is an effective pain killer, blocking nerve conduction fibers that produce pain. It reduces inflammation and swelling by reducing inflammatory chemicals. It improves blood supply to an area of injury by dilating blood vessels and increasing delivery of oxygen and by reducing blood platelet stickiness. It stimulates healing, which is a key to its usefulness in any condition. It is among the most potent free radical scavengers known to man, if not the most potent one. This is a crucial mechanism since some molecules in our bodies produce an unequal number of electrons and the instability of the number causes them to destroy other cells. DMSO hooks on to those molecules and they are then expelled from the body with the DMSO.



DMSO also penetrates the skin and the blood-brain barrier with ease, penetrating tissues, and entering the bloodstream. Furthermore, DMSO protects the cells from mechanical damage and less of it is needed to achieve results as time passes as oppossed to most pharmaceuticals where increasing doses are required. It has a calming effect in the central nervous system and it reaches all areas of the body, when absorbed through the skin, including the brain. That is, DMSO applied to one area often leads to pain relief in some other location due to its systemic effect.

It acts as a carrier for other substances or drugs and it also potentiates their effect. In fact, certain drugs dissolved in DMSO, such as corticoids, antibiotics and insulin, may be used in a lower dose than usual without reducing their therapeutic efficacy and in addition, their undesirable side effects are greatly diminished. Also, drugs are able to pass through the blood-brain barrier which is usually impenetrable.

DMSO promotes the excretion of urine and functions as a muscle relaxant. It boosts the immune system, increasing the production of white cells and macrophages that destroy foreign material and pathogens in the body. It also has anti-bacterial, anti-viral and anti-fungal properties. DMSO also increases the permeability of cell membranes, allowing a flushing of toxins from the cell.

DMSO has radioprotective properties against lethal and mutagenic effects of X-rays in cells, cellular systems and whole animals. It also has cryoprotective properties, meaning that it is capable of protecting against injury due to freezing.
DMSO has also been shown to have anti-cholinesterase properties (Sams, 1967), in other words, it inhibits an enzyme from breaking down acetylcholine, increasing both the level and duration of action of this important neurotransmitter. Acetylcholine is responsible for learning and memory and is also calming and relaxing. Acetylcholine is also a major factor in regulating the immune system, acting as a major brake on inflammation in the body.

As a source of sulfur, DMSO aids in heavy metal detoxification. Sulfur binds with toxic heavy metals (mercury, lead, aluminum, cadmium, arsenic, nickel) and eliminates them via urination, defecation and sweating.

FDA and Big Pharma Obstacles

DMSO is sold in health food stores, mail-order outlets, on the Internet, and in most countries around the world. It is used by millions for its health benefits yet in the U.S., DMSO has FDA approval only as a preservative of stem cells, bone marrow cells, and organs for transplant, and for interstitial cystitis – a painful inflammatory condition of the bladder which is very difficult to treat with other therapies.

That DMSO has not found favor as a remedy for other medical conditions is partly due to the inability to test it in double-blind experiments. Blind studies, as the name suggests, requires that a study be done without knowing which patient is taking the placebo or the drug. In the case of the DMSO, a blind study is impossible since the peculiar garlic-like taste and smell (no matter the route of application) gives it away and no satisfactory placebo could be devised that would mimic this particular effect of DMSO (Steinberg, 1967).

The FDA and big pharma would prefer we remain dependent on their drugs.

If you search for DMSO on the U.S. National Library of Medicine (, you’ll get almost 30,000 indexed results, making it one of the most studied compounds of our time. Yet, we are led to believe that DMSO can’t pass the required regulations for its approval in other medical conditions even though its effectiveness and low toxicity profile is unquestionable.

You see, DMSO is a common chemical that can be manufactured cheaply. No drug company can get an exclusive patent since it is also a natural compound, therefore there is no significant financial return. In fact, an executive of a major drug company is quoted as saying, “I don’t care if DMSO is the major drug of our century and we all know it is, it isn’t worth it to us” [CBS TV show 60 minutes with Mike Wallace, The Riddle of DMSO]. If DMSO were to be approved by the FDA, it would be competetive and drug companies would be unable to hold the patents. In the words of the director of the Bureau of Drugs of the FDA, J. Richard Crout, M.D., “DMSO is a low toxicity and safe compound (…) I think that it is a fact of life that drug companies are not going to invest in something unless they think there is some financial return” [CBS TV show 60 minutes with Mike Wallace, The Riddle of DMSO].

Despite restrictions on the use of DMSO, thousands of Americans purchase it on the ‘black market’ each year, its popularity due not to publicity, but rather ‘word of mouth’. When you have something that relieves all kinds of ailments, including some life-threatening ones, people naturally recommend it to friends and family!

In Perspective

In the 1960s, research with DMSO on humans was temporarily halted after certain animals treated with DMSO were found to have changes in the eye lens. Some of these changes resembled those seen in aging dogs (Gordon, 1967), but nevertheless, research was gradually restarted after no evidence was found of eye changes in humans. As Daniel Haley reports in his book Politics in Healing: “Tests in rabbits, dogs, and pigs (but not humans) had shown some problems. When quantities of DMSO equal to about ten times the maximum human dose were given every day over a period of six months, slight changes in the lenses of the animals’ eyes would result, enough to produce a slight nearsightedness. The lens changes were not enough to cause dogs difficulty when running – they didn’t bump into things – and in some cases, the changes disappeared after the massive DMSO doses were stopped. In no test at that time or since has DMSO ever caused cataracts, either in animals or in humans” (Haley, 2000).

In fact, DMSO is effective for macular degeneration and retinal disease, both diseases of the eye. This effectiveness was first discovered when patients with retinitis pigmentosa, a retinal disease, were taking DMSO for certain musculoskeleteal disorders. They sensed that their vision had improved and some had remarkable results (Morton, 1993).

As far as eyes are concerned, the evidence on DMSO is quite to the contrary. When several patients treated with DMSO for muscular problems reported to Dr. Jacob that their vision had improved, he sent them to Dr. Robert O. Hill, ophthalmologist at the University of Oregon Medical School. Confirming the favorable changes, Dr. Hill began his own experiments with DMSO (after it was known that the lens changes did not happen in humans). His research showed drops of 50% DMSO to be effective in retinitis pigmentosa and macular degeneration, and presented a report on this at the New York Academy of Sciences symposium in 1971. (Haley, 2000)

In contrast, the number of medication-related deaths in the U.S. is estimated at over 200,000 a year, making medications the third or fourth leading cause of death (Pezzalla, 2005). Even common pain relievers called NSAIDs, examples of which include Advil, Motrin, Aleve and aspirin, account for an estimated 7,600 deaths and 76,000 hospitalizations in the U.S. every year (Tamblyn et al, 1997). Taking this into consideration, it is safe to declare that DMSO is among the safest substances in the world today. In fact, the classic test for toxicity -the LD-50 test – measures the lethal dose (LD) at which half of a group of test animals is killed. The LD-50 tests for aspirin and DMSO show that aspirin is seven times more toxic than DMSO (Haley, 2000).

Quick Guide and Ailments

DMSO is generally applied to the skin in a gel, cream, or liquid. It can be taken by mouth or as an intravenous injection, in many cases along with other drugs. It has also been administered subcutaneously, intramuscularly, intraperitoneally, intrathecally, by inhalation, instilled into the eye, on the mucous membranes, and into the urinary bladder. Strenghs and dosages vary widely.
If you are just dealing with pain or an injury, use a topical application. Don’t drink it. Drinking it is for serious detoxing and other internal necessities. If you use a rose scented DMSO cream, chances are that nobody will be able to smell DMSO’s garlic-like smell.

DMSO being distilled.


The usual oral dose of DMSO is one teaspoon per day of DMSO 70% (Morton, 1993). But since it can trigger detoxification reactions and DMSO’s total excretion from the body can take several days, it is best to do it only once a week. Start with half a teaspoon of DMSO 50% and increase to a teaspoon of DMSO 70% only if any possible detoxification reaction is well tolerated.

When you use liquid DMSO in the skin, let it dry for over 20 to 30 minutes before wiping the rest out. The skin must be clean, dry, and unbroken for any topical use of DMSO. The face and the neck are more sensitive to DMSO and no higher concenrations than 50% should be applied there. Topical concentrations of DMSO should be kept below 70% in areas where there is a reduction of circulation. When 60 to 90% DMSO is applied to the skin, warmth, redness, itching, and somtimes local hives may occur. This usually disappears within a couple of hours and using natural aloe vera, gel or cream, will help counteract or prevent this effect. When 60 to 90% DMSO is applied to the palm on the hand, the skin may wrinkle and stay that way for several days.

“My brother put some DMSO gel (70% dmso, 30% aloe vera) on his shoulders and lower part of neck because he had muscle pain/soreness in that area, and it caused skin redness/irritation for a few hours, although it did diminish the muscle soreness as well…my grandma has rheumatoid arthritis that made her legs swell up and hurt continuously, and I had her apply the same DMSO gel, and after about 2-3 days of applying it once a day, the swelling was 90% gone, and I think within 4-5 days it was 100% gone, and she said the pain diminished as well.” – Michael Shatskiy, Los Angeles, California, United States

Chronic pain patients often have to apply the substance for 6 weeks before a change occurs, but many report relief to a degree that had not been able to obtain from any other source. In general, the greater the chronicity of the disorder, the longer the treatment with DMSO must be employed in order to achieve palliation (Steinberg , 1967).

Common health problems for which people will apply topical DMSO at home include acute musculoskeletal injuries and inflammations. The earlier DMSO is used, the more dramatic the result. A 70% concentration of DMSO mixed with water in volumes ranging from 8 to 12 ml, applied on and around the injury in a wide area at least three times daily, will have a healing affect in 4 out ot 5 people.

Arthritis, Sprains, Strains

It provides rapid amelioriation of pain and increased mobility and reduction of inflammation when used topically. You can see a positive response within 5 to 20 minutes and usually lasting for 4 to 6 hours. (Steinberg, 1967).

“Applying DMSO where it hurt to a six-year-old wasted from rheumatoid arthritis, in a half hour the child could move her shoulder and turn her head for the first time in two years. Persuaded to try walking, she managed a few steps and then burst into tears. “Why are you crying?” Dr Jacob asked her. “Because it doesn’t hurt anymore”, she replied. (Haley, 2000)

“My brother has arthritis of the spine. He is in pain and bedridden more than half the time. When he is treated with DMSO, he is able to lead a normal, active life… Just one application of this cheap, safe DMSO changed my brother from a grimacing patient into an active, pain-free man in exactly 30 minutes!” (Haley, 2000)

June Jones, once quarterback and later coach of the Atlanta Falcons pro-football team, had a bursitis calcification in his right shoulder. His career almost didn’t happen as he could hardly lift his arm, let alone throw a football. But he was aware of DMSO and had used DMSO for sprains, like thousands of others. He received a shot of DMSO in the shoulder and after using DMSO for 30 days straight, the calcification disappeared. (Haley, 2000)


Given soon after a stroke, DMSO can dissolve the clot that causes the stroke, restoring circulation and avoiding paralysis. Once DMSO gets into the body either daubed on the skin, given in I.V., or by mouth, it permeates the body and crosses the brain barrier, so even taken orally it can improve circulation. Ideally it should be I.V.

DMSO products

DMSO is available in various formats.


Even though DMSO 40% causes a prolongation of bleeding time, it is still indicated for use in treating embolic or hemorrhagic stroke. DMSO is superior to any other treatment for wounds to the brain where a great deal of bleeding is present (Morton, 1993).

One man who had a stroke at 7:30 AM refused to go to the hospital until after his wife had spoken with Dr. Stanley Jacob, which didn’t happen until 6:30 PM. Starting at 7 PM the day of the stroke, she gave him one ounce of 50% DMSO in a little orange juice every 15 minutes for two hours and then every half hour for two hours. The next day, her husband was better and soon returned to normal. A substance that can stop a stroke as it’s happening is something many might want in their home medicine chest .(Haley, 2000)

Angina, Heart Attacks, Injuries of the Brain and Spinal Chord

DMSO may help neutralize harmful effects on the heart and brain in medical disorders involving the head and spinal chord injury, stroke, memory dysfunction, and ischemic heart disease (Jacob, de la Torre, 2009). A 40% DMSO solution should be administered within four hours to be effective, within ninety minutes is best.

After I.V. administration of DMSO, there is an elevation in the amount of spinal cord blood flow to the region of trauma. One of the first things that happens after spinal cord trauma is that a reduction of oxygen and blood flow sets in, inasmuch as the blood vessels constrict or shut down… Without some treatment, the tissue swells. Eventually, this leads to paralysis. In a cerebral stroke, the animal will either become comatose or lethargic or die. With DMSO infusion immediately after injury (or stroke) all this is prevented. – Dr. Jack de Ia Torre, professor of physiology and neurosurgery at the University of New Mexico

Dr. Stanley Jacob has even given DMSO intravenously to people who were already paralyzed – paraplegics – and some regained use of limbs. One man, quadraplegic, recovered enough to go through college and then to work in a bank. (Haley, 2000)


When combined with antibiotics, DMSO will convert bacteria which are resistant to a given antibiotic to being sensitive to that same antibiotic and probably a 80 to 90 per cent solution of DMSO will be required in order to be clinically useful ( Pottz, Rampey, Benjamin,1967). DMSO has been used to transport antibiotics to hard-to-reach areas of the body with excellent results, such as the bone marrow and brain (Sanders, 1967).

DMSO can dissolve a virus protein coating, leaving the virus core unprotected with its nucleic acid exposed to the immune system. Applied topically, it alleviates the lesions that occur as a result of Herpes Zoster, shingles (Morton, 1993).
Placed into the nostrils or topically in the face, DMSO can open blocked sinuses within a few minutes and it has been used with sucess in patients with polyps (Marvin, 1967).

DMSO can clear up gum disease and reduce tooth decay and their pain by painting it on the involved areas.

“I have some pharmaceutical grade DMSO and I pour about two teaspoons in a glass in the evening, put my 20 mg of doxycycline in it, add about 2 teaspoons of distilled water, and then swish it around in my mouth for about 2 or 3 minutes and then swallow it. So I guess it is about 50% solution. It’s really working on my mouth. That inflamed area of my jaw has calmed down about 70% in just a couple of days. Or more, actually. I expect it to be completely soothed by tomorrow after tonight’s dose of DMSO.” – Laura, Toulouse, France

Keloids, Scars, Burns, Bruises

A concentration of 50 to 80% put on two or three times a day will flatten a raised scar after several months. It is of considerable value in superficial burns (Goldman, 1967) and when applied quickly to an injury, it can eliminate any bruising.

“I have been applying it to my face for two weeks… I had a bout of acne in March, and this healed the damage pretty well but what amazed me is that my hyperpigmentation (melasma) has also faded very noticeably. In fact, it’s amazing!” – HG, United States

“I diluted a 50% solution and applied it topically to the inflamed lymph node. I applied it again this evening. I am totally amazed! There is a noticeable decrease in the size of the node, in just two applications! And it no longer feels matted. This node has been swollen for over 20 years!!! – Melissa Medlock, Coldwater, Michigan, USA


DMSO can be effective in the treatment of painful corns, calluses, ingrown toenails, bunions, hammertoes, heel spurs, and the inflammation of gouty big toes.

Varicose veins and thrombophlebitis

Topical DMSO can whiten telangiectasias, small dilated blood vessels near the surface of the skin. It can also decrease the size of varicosities in the legs and the inflammation that goes with it, along with a relief of their cramping discomfort (Marvin, 1967. Blumenthal, Fuchs, 1967).

Eye problems

One drop of a 25% DMSO solution (diluted in sterile physiologic or saline solution) once or twice per day is useful for eye problems, including cataracts or glaucoma.

“DMSO is amazing, I’ve also read various good results with using it in the eyes. Being the adventurous type myself, today I diluted DMSO down to 30% and put 2 drops in one of my eyes that has been having red spots around the iris. The red spots diminished drastically. The only side effect was a slight burning sensation, similar to those drops you get when one goes for a glaucoma test, without the side effect of dilated pupils.” – DZ, United States


DMSO is highly effective in vascular headaches and in muscular tension which so often goes with headaches. It may be used on hairy areas such as the scalp and it also may be used near the eyes. A 90% solution is more effective (Ogden, 1967).

Mental Disorders

DMSO has been useful in the treatment of patients with the following diagnoses: (1) overexcited states (acute schizophrenic reactions, manic phase of the manic-depressive psychoses, alcoholic psychoses, symptomatic psychoses); (2) some symptoms of the chronic psychoses (autism, stereotypia, negativism, abnormal behavior or delusional states) ; (3) severe neuroses (anxiety reactions, obsessives)( Ramírez, Luza, 1967).

McGrady called special attention to an extraordinary paper presented by Dr. Eduardo Ramirez and Dr. Segisfredo Luza of the Ayetano Heredia University in Lima, Peru. After extensive tests on animals and then on normal humans, Dr. Ramirez reported “injecting 50% or 80% DMSO intramuscularly into patients with acute and chronic schizophrenia” and that “of the 14 acute cases, every single one was discharged from the hospital within 45 days after the start of DMSO treatment… He said that 4 of the 11 chronic cases, one of whom has been ill for 14 years, were discharged eventually, and the other 7 improved a great deal and were given occupational therapy… He observed rapid decrease in agitation… recession of persecution feeling, a relatively sudden tendency to communicate and to stay clean.., the wane of obsessions, return to alertness, and a calmness where there had been restlessness and anxiety”. (Haley, 2000)

Genitourinary disorders

DMSO has been used in the treatment of a number of patients with various genitourinary disorders, including Peyronie’s disease, interstitial cystitis, acute epididymitis. Some have obtained dramatic and gratifying relief of symptoms (Persky, Steeart, 1967).


DMSO in conjunction with other treatments has shown to regress cancer in a very effective way (Ayre, 1967). Intravenous administration of DMSO markedly reduces pathological intestinal permeability while preserving the gut’s absorption capacities (Wang et al, 1996). Considering that gut permeability (‘leaky gut’) has a fundamental role in chronic degenerative diseases, this is of great clinical importance.

DMSO also has excellent results in the skin of people afflicted with scleroderma, results which have never been observed with any other method of therapy (Scherbel et al, 1967).

Mrs. Jean Puccio of Washington, DC testified at hearings of Senator Edward Kennedy’s sub-committee on health in 1980 on her recovery from scleroderma. Diagnosed in 1971, she was told that no medication would help, and that she would probably soon face a wheelchair and early death. By the time she found Dr. Jacob (through word of mouth), she told the Senators, “I was having difficulty breathing, walking, and eating”. The disease “thickens the tissue and makes your skin so tight you cannot move. It was difficult for me to drive, to turn the ignition in my car or turn my body”. Her dentist could not work on her for awhile because she could not open her mouth. “Now I can open my mouth like anybody”, she said. After her sensitized skin burned from topical application of DMSO, Dr. Jacob suggested taking it orally. “Within six months”, she testified, “my condition reversed almost immediately. I can do anything anybody else can do now” (Haley, 2000).

Hopefully, this brief overview of DMSO’s great capabilities has helped to illustrate how it is indeed, the cure of our times. I’m convinced of its therapeutic power, both by my own experience and that one of scores of people, not to mention the back-up of published scientific literature. Its uses and applications make it a very handy compound to have on your medical shelf. In pure form, the life of DMSO is indefinite, so it may be used for years.


Several books have been published on the benefits of DMSO.



The garlic-like body odor and taste in the mouth that some experience is attributable to a specific DMSO metabolite: dimethyl sulfide (DMS), a component of natural onion and garlic flavors (McKim, Strub, 2008). This can last for one or two days and in a small number of people, especially men, the odor can be very pungent. Drinking enough water will help diffuse the smell. Other side effects – such as stomach upset, headaches, dizziness, and sedation – are very likely related to detoxification reactions prompted by the DMSO.

Only purified and properly diluted DMSO should be used. When you dilute a pure DMSO solution, always do it in distilled water. When it is applied, the skin site as well as the applying hand should be thoroughly cleaned before application. This is of utmost importance as DMSO’s properties allow contaminants to be absorbed through the skin and transported into the bloodstream.
DMSO is known to be one of the least toxic substances in biology (Parcell, 2002), so any serious side effects should come from potential contaminants or the intake of concomintant drugs that DMSO will carry into the body. Worth repeating again, DMSO and any substance dissolved in it, will penetrate the skin, the blood-brain barrier, and other parts of the body very fast.

Remember also that DMSO increases the effects of drugs like blood thinners, steroids, heart medicines, sedatives, etc. In addition to that, acetone or acid contamination of DMSO can lead to serious medical consequences. Be aware of this problem when buying unreliable DMSO. A pure DMSO solution will turn solid (like ice) in the refigerator within 2 hours. If, when the frozen bottle is turned upside down, little rivulets of water flow through the ice, you probably possess the veterinary grade DMSO. This is a 90% concentration. Ten percent is distilled water (Morton, 1993).

Women are discouraged from using DMSO during pregnancy or breastfeeding, even though DMSO is used to preserve frozen human embryos. DMSO can interfere with liver function tests and give a false reading. That problem is easily solved by waiting a week after DMSO usage before taking the test.

Long-term use has been documented as safe. Eye damage, reported in laboratory animals, has not been confirmed. Side effects such as skin rash and itching after topical application, breaking up of blood elements after intravenous infusion, can be avoided in large part by employing more dilute solutions. Despite these side effects, DMSO is used as a preservative for blood elements and stem cells (McKim, Strub, 2008).

When DMSO is diluted with water, heat is released. The bottle will be warm to the touch. This is a temporary, harmless reaction.
Since DMSO causes dryness and scaling of the outer layer of the skin, skin diseases characterized by scaling (psoriasis) could be aggravated by the use of DMSO. But DMSO applied topically for only a few days has been useful in psoriasis. Prolonged use of DMSO for the treatment of psoriasis is not advised however, as it can worsen the psoriatic condition (Engel, 1967), only DMSO taken orally is suggested.

“I’m happy to say that taking DMSO in conjunction with implementing the detoxification suggestions that were given is starting to take care of many of my remaining psoriasis problems. A couple areas are still being stubborn, but I’ve noticed a lot of general improvement. Using DMSO topically also helped improve a patch of eczema that my wife has been bothered by for quite a while.” – Peter Norquest, Tucson, Arizona, United States

DMSO2, a derivative of DMSO, is better tolerated and doesn’t have the odor and irritation side effects. Despite this positive aspect, it hasn’t surpassed the effectiveness, fascination and popularity of DMSO. It is also known as methylsufonlmethane or MSM, an entire topic for another article by itself!

Sulfur is an element of the earth and it is essential to life, it as among the most prevalent elemenents in the human body. Allergic reactions to sulfur are not possible because sulfur has no protein component. When people are ‘allergic to sulfur’, what they really mean is that they are allergic or sensitive mainly to certain sulfur-containing drugs or proteins, most notably sulfa antibiotics (sulfonamides) or to sulfites (preservatives used in wines and some foods), or to foods with a high sulfur content (broccoli, cauliflower, garlic, onions, etc). Many individuals with allergies to sulfa drugs, sulfites, or high sulfur containing foods (like the author) do not experience problems taking DMSO, because apart from sulfur, DMSO bears no relation to these substances.

As always, proceed with caution, do your homework, and consult a health care provider in case of doubts.


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  1. Bruno Troccoli  September 19, 2014

    Can DMSO be taken oraly. If so how. Thank you so much for your help

    • Gabriela Segura, MD  September 19, 2014


      It can be taken orally, although it can trigger a bad detox reaction and it can dehydrate your gut lining. Topical is effective enough.

  2. Kiruba  October 23, 2014

    Hi.. Can I use 30% DMSO for my sinus polyps. its killing me.

    • Gabriela Segura, MD  October 23, 2014

      I would use between 20% and 30%, more diluted to stay on the safe side. It has had great results in polyps, but do check out dietary changes for better results (i.e. Ketoadapted by Maria Emmerich).

  3. christine  October 24, 2014

    Had wrist surgery however my elbow and forearm has been killing me and the nerve pain is very serve. What do u recommend? 50% DMSO ROLL ON TO SKIN? you opinion is much appreciated I look forward to your response.

    Thank you

    • Gabriela Segura, MD  October 24, 2014

      Either that or any other type of DMSO solution/cream. Christine, make sure you are eating an anti-inflammatory diet, it will help you recover faster. See for instance “Ketoadapted” by Maria Emmerich. All the best!

  4. Jason  November 6, 2014

    I have read that DMSO is a great fighting agent against herpes (HSV 1 & 2) is this correct? If so, what is the proper application. I have read applying to the lower back/spinal area as well as on the genitals, before or during an outbreak. I would prefer getting the information from a professional. Thanks!!

    • Gabriela Segura, MD  November 6, 2014

      Yeah, there is a section on herpes on this very article. On sensitive areas, I would not apply a solution stronger than 50%. It works very well for herpes. You could also choose the cream version, it is more gentle.

  5. David  November 6, 2014

    Trying to locate a source for Sterile DMSO for Intravenous use. My daughter has scleraderma and this is the only solution. Stanley Jacob stopped selling it. We need another source!

    • Gabriela Segura, MD  November 6, 2014

      That is very bad news. I would look into pharmaceutical grade DMSO, ask the labs and/or pharmacies. It is still used in veterinary medicine, so it is still made.

  6. AJ  November 9, 2014


    I was looking at DMSO and MSM for a couple reasons. 1. for facial scars (pitted) I had from chicken pox when I was younger and currently have rosecea and 2. Hair regrowth (MPB). What are the best dose solution of DMSO for this certain issues? Thanks

    • Gabriela Segura, MD  November 9, 2014

      You can get any recommended MSM. For DMSO, cream is the best choice for the face. Might not be so effective as the liquid solution, but sometimes easy does it. For rosacea, dietary changes is the best choice. See “Ketoadapted” by Maria Emmerich. All the best!

  7. Claes Edshammar  November 13, 2014

    Like to learn more of dmso and msm, wonder if it can help for dislexia.

  8. Don Boles  November 14, 2014

    I’m a 68yo male who recently had a series of vascular screenings. The results showed that I had a 7.1cm x 7.2cm AAA which we immediately fixed with endovascular surgery. The other tests revealed that I had a positive calcium score of 209(was 59 ten years ago), bilateral carotid plaque, right greater than left, elevated C-reactive protein(a marker of inflammation), total cholesterol of 244(I had stopped my statins about 15 months ago when total cho. was 155), and I have prehypertension with my avg. being +/-127/78. About 15 months ago, I also started a ketogenic/Paleo eating plan to lose weight and to promote anti-inflammatory foods. I’m also a fan of DMSO. It stopped my peridontal problems, it stopped the occasional pain of a torn rotator cuff and tendinitis elbow, quickly healed cuts, bruises & tender muscles sometimes gotten from my fitness-kickboxing workouts. Here’s my question relative to DMSO and my recent cardiovascular discoveries……Any tips on how can I effectively use DMSO to lessen the inflammation associated with my recently discovered atherosclerosis issues…..ingestion and/or topical applications??

  9. Pamela  December 6, 2014

    I forgot to click the “notify me by email ” box when i submitted my question. If there is a way to change that, please do so. Otherwise, I will check back daily.

  10. Joe White  December 6, 2014

    Can I treat periodontal disease in a dog by mixing a 10 to 20 % solution in the food?

  11. Pamela  December 9, 2014

    I’m not sure my questions made it through the first time, so here is a little background first:
    My 12 yr. old dog (Blue Tick mix) developed a tumor on her foot this July, which I had removed. It came back this Fall with a vengeance. Not only on the bottom of her foot, but another grew on the top in the ankle area, which she licked the skin right off of. Plus now she has two more just above that one, and who knows what’s happening on the inside. I’ve not had lab tests done, but only an idiot wouldn’t call this cancer. Yes, she has seen her vet.
    I’ve been trying several different natural things with her, including the 8 herb Essiac tea (now up to 12 oz./day), Zeolite powder, turmeric, baking soda/molasses, etc., but nothing has helped and it has gotten worse — FAST! The tumor on the top of her foot has grown to 3-4″ in diameter from the size of a walnut in a matter of about 6 or 7 weeks. I keep her foot/lower leg covered, using telfa pads and feminine napkins to handle the fluid and small amount of blood coming from the tumors. I call it the “Horror Show” on her leg.
    She is taking steroids, which I’m not a fan of, except that they help her to get up and eat and drink more water than she was without them.
    I now have a bottle of DMSO (Jacob Lab), and I would like to use it in the best way for her. I also have 35% food grade peroxide.
    Can I combine these two? If so, how do I administer them to her — i.e. how much, orally or transdermally, or both? If orally, do I mix them in something like broth, or juice, or sweet, so as to create a “Trojan horse” effect? With food, or on an empty stomach?
    Would it be wise to mix a few (3-5) drops of each together with the baking soda/molasses paste I’ve been giving her?
    Do I need to shave a spot on her to insure the area is clean if I put it on her skin?
    Would her belly be a good spot to put the DMSO?
    Do I need to cover the area afterward, with a piece of gauze or something, so her skin doesn’t come into contact with something that may be “pulled into” her system by the DMSO?
    I don’t think it would be good to put it directly on the largest tumor, as it is extremely “raw”.
    I appreciate any advice you can guide me with, so I can use the DMSO in the best way for my dog.
    Thank you for your time!

    • Gabriela Segura, MD  December 9, 2014

      I would not mix DMSO with anything that could be dangerous for the dog, but would try the topic possibilities first. The dog will probably leak it too, that is okay, and it doesn’t need shaving. I would not apply it where there are ulcerations, but around. There must be plenty of water around in case of dehydration. Do read the following post for crucial info:

      Hope this helps.

      • Pamela  December 10, 2014

        Thank you Doctor. I started her on Vitamin C this morning. I found it easy to use the peroxide (diluted) on her tumor (and leg) to clean it, then apply the DMSO to the back of her leg, opposite the tumor. I did not mix the two, but wanted to make sure the area was clean before applying the DMSO.
        She has been on a grain-free dry food diet for a month or more, to which I add a lot of water — since she loves the “broth”. She is also drinking more water since she started on the steroids.
        Question: Do steroids do more harm than good in a case like this?
        Thank you!

      • Gabriela Segura, MD  December 11, 2014

        It depends on the context. Steroids can be like a fertilizer for tumor cells depending on the dose. But nothing is black and white, it can be lifesaving when there is a clear indication. All the best!

  12. Jamie  December 17, 2014


    I’ve been dealing with CRPS in my feet for about 18 months. Docs think the trigger is scar tissue pushing on my peripheral nerve – and for some reason it is sparking CRPS. The trouble is surgery is incredibly risky with this condition.

    At the moment I’m in pretty bad shape – in a wheelchair. Desperate to get myself out of this – and in the most natural way possible.

    I’ve read a bit about DMSO for CRPS. Are you at all familiar? Curious about dose and frequency.

    Many thanks.

    • Gabriela Segura, MD  December 18, 2014

      In you case, I would start with topical DMSO cream, rose cream version. If that soothes and relieves, I would venture with the 50% DMSO dilution, applied with a cotton.

      I’ve met a woman who got enormous relief for your condition with capsaicin patch 8%. A health care provider has to place it and there are mixed results, some don’t improve, others even feel worse. I just happened to know someone who almost cried from the relief she got.

      To be on the safe side, you can try the DMSO cream first. Best!

      • Jamie  January 8, 2015

        Thanks Gabriela. So the cream is gentler than the 50% dilution – even though the cream says 70% DMSO?


      • Gabriela Segura, MD  January 8, 2015

        That is actually the case and the dilution might work better.

  13. james  January 8, 2015

    ive used DMSO from two different brands both when ordered it ive read up on the reviews that had alot of good feed back but i dont seem to have that garlic taste at all, so how do i know its actually true DMSO and its penertrating the skin? Is that somthing you can answer?

    Thanks james

    • Gabriela Segura, MD  January 8, 2015

      Ask someone else if they can smell something odd about you. The other way is by evaluating your clinical response. Believe me, it does penetrate.

  14. Andrew mAchado  January 8, 2015

    Hey, I am trying to use DMSO to cure hsv1-hsv2 in myself and my girlfriend who also has diabetes. What % should I use it is it possible to get to get pure 98.8 and create my own cream possibly by adding some drops to a bit of all natural cold pressed coconut oil or aloe. Should we use it orally and topically? Thank you so much for your time.

    • Gabriela Segura, MD  January 9, 2015

      50% topical option sounds the best for starters. If the irritation is tolerated, a 70% solution can be used. DMSO can be combined with any safe natural products, however I don’t think it will mix well with coconut oil. It has been tried before with mixed results. You can experiment though and/or use coconut oil separately.

      I highly recommend you both read “Ketoadapted” by Maria Emmerich available on kindle. The diet is the best one to deal wit viral infections and diabetes as well.


      • Andrew mAchado  January 9, 2015

        Thank you so much. And could it be used on lips and in vaginal entrance? Would it burn her or just on tips of spinal cord? Any other tips? You are very much appreciated!

      • Gabriela Segura, MD  January 10, 2015

        You can use DMSO anywhere, but beware of the burning sensation. That is why it is best to start with 50% dilution or a milder presentation, i.e. creams.

      • Bill  January 15, 2015

        I’ve been using a mixture of coconut and olive oil (one to one) with about 25 to 30 percent DMSO for all sorts of things (cuts, infections, bruises, fungus, tooth pain, etc.) It works great, you just have to shake it well because they separate.

    • Skin Researcher  January 30, 2015

      Please look into Berberine for diabetes. This is your best bet. It is effective, natural, and should also improve the health of your entire system.

      It is effective enough that some doctors that have been notified of its existance (most have not, because it is natural, ie, “alternative”) have started to suggest it instead of Metformin.

      Hope this helps.

    • Connie  July 21, 2018

      research about oregano oil killing herpes virus.

      • Bobbie  July 21, 2018

        Hi Connie,

        I had a bad experience with diatomaceous earth. I took a little each day to cleanse but after a week I started suffering from bone loss so had to stop and never used it again. Just a warning. I never had a problem with essential oils. Take care :)

  15. Andrew  January 9, 2015

    Also, would you recommend a certain brand of DMSO because I am hearing about industrial grade and I don’t want a bad one.

    • Gabriela Segura, MD  January 10, 2015

      Any presentation sold by a reputable health website or store has had the reputation of being safe, i.e. the ones presented on the pics.

  16. Ruben D Ramirez  January 11, 2015

    Hola Dra Gabriela:
    En caso de cefalea vascular cual seria la presentacion que Ud mas recomienda ?
    oral o topica.


    Ruben Dario

    • Gabriela Segura, MD  January 11, 2015

      Hola Ruben, Yo lo haría en crema sobre las temples o donde más duela. También tomaría 2 cápsulas de malato de magnesio y evitaría el monosodio glutamato, comidas procesadas y altas en hidratos de carbono, así como el gluten y la caseína.

      • Bill  January 15, 2015

        Can we see a translation? I’d like to know what the reference to monosodium glutamate is.

  17. Phoebe  January 20, 2015

    I wonder if you have heard of DMSO being used for Multiple sclerosis or Narcolepsy
    Would you apply it on the spine for MS? Narcolepsy is a sleep disorder focused in the sleep center of the brain would I apply at the base of the hair line?

    • Gabriela Segura, MD  January 21, 2015

      Hello Phoebe,

      All fascinating research concerning DMSO in debilitating clinical conditions was halted after the 70s thanks to the control system (i.e. FDA). People continue to research on their own, but nothing that would be published in mainstream medical journals as it was done during the 50s and recounted in this article. You can check out this video to get an idea of DMSOs potential:

  18. shoma balleram  January 27, 2015

    live in trinidad and tobago how can i get DMSO

  19. Skin Researcher  January 30, 2015

    DMSO does have many proven healthy benefits.

    HOWEVER, it is a solvent. It is an intense solvent. It penetrates to the bloodstream effectively and quickly. This is wonderful when you are using it to penetrate a useful active.

    But whatever else is already on your skin, or whatever else your skin comes into contact with over the next 36 hours, will penetrate directly into your bloodstream. This is very dangerous. They first discovered this in a clinical trial where they were cleaning the skin area of application with rubbing alcohol prior to DMSO application. The rubbing alcohol ended up immediately in the blood stream of the participants. This phenomena has been restudied and confirmed.

    The complications of this are innumerable. We do not want to absorb most detergents, chlorine from our water, toxins from our air, etc.., immediately into our bloodstream.

    Be very careful when using this substance. Dilute it as much as possible while still getting enough to notice relieve. Additionally, find a source in a glass bottle, instead of plastic. The plastic containers do have special linings, but they are still chemicals and plastics that you do not want absorbed into, and then building up with repeat use, your bloodstream and body.

  20. Linda  February 2, 2015

    Hi, Dr.
    My little dog has been favoring her front paws, licking them extensively; also her hindquarters.
    She has not responded to allergen treatments from the vet.
    So I’m wondering. Could I dilute DMSO (with what?) and use that on her? A spray would be optimal because of her coat. I also am worried that she may lick the solution. Would that harm her?
    It also has crossed my mind that she may be getting mange. Would the solution help that, too? She’s driving me crazy constantly biting at herself, yet there are no fleas or ticks on her.
    Your input will be much appreciated. Thanks, Linda

    • Gabriela Segura, MD  February 2, 2015

      Hello Linda, Have you tried changing her diet? Raw meat diet is the way to go. You can check this post in its comments for more info on an optimal doggie diet:

      A Scottish Terrier Miraculous Recovery from Bladder Cancer

      As for the DMSO, yes, she will probably lick the solution. For that reason, I would try a very diluted DMSO, i.e. 30%. Just keep in mind that the solution might crystallize, so the spray might be hard to use. Keep enough water available in case the DMSO dehydrates the dog.

      Hope this helps.

      • arcadia11  February 2, 2015

        hi dr. segura –

        i hope you won’t mind my recommending a second option, in addition to the raw food diet, for linda’s little dog.

        last year mange or a mange-like condition (morgellon’s?) was epidemic here in northern california. short version of the story – i found several treatments for such on
        earthclinic. i made up one of the solutions for several dogs in the neighborhood and it worked well. the exact formula can be found on earthclinic but it is simply borax
        dissolved in water – i don’t remember the amounts but i think it was about a half cup of borax – and a little hydrogen peroxide. there are several other substances that are helpful as well, described on the website.

        my dog got it too but not as badly as those who were fed canned food or the dreadful kibble. he responded well to the treatment.

        thanks and good luck to linda and her dog.


      • Gabriela Segura, MD  February 2, 2015

        That is great! I hope you contribute more often.

      • arcadia11  February 2, 2015

        lol and thank you. sometimes i simply cannot be silent.

        kindest regards –

  21. annoyng  February 4, 2015

    Hi, i buyed dmso 99% and i want to use it for two reason:
    first) for my shoulder pain, i practice bodybuilding and my shoulder is very painful because impingment problem of sovraspinatus tendons
    second) i want to mix it with yohimbine lquid extract for burn fat in my abdominal area not vascularized.
    do u tell me how to use it?

    • Gabriela Segura, MD  February 4, 2015

      I don’t have experience with yohimbine liquid, but as a general rule, don’t mix it with anything you don’t trust or are unsure.

      I invite you to read “Ketoadapted” by Maria Emmerich for some vital information on how to burn fat most effectively. The book also provides info on how to help your shoulder with an anti-inflammatory diet.

  22. Rusty  February 6, 2015

    Dr. Segura,
    My dad and I get Basil cells and other skin growths on our foreheads, yes, we are fair skined Irish men.
    What amount of DMSO would be best for killing that? Liquid or cream etc.
    Wasn’t sure if I should use Aloe with 50% DMSO. Also, how often should it be applied?
    Thanks so much!!

    • Gabriela Segura, MD  February 6, 2015

      For any skin growth, you’ll need liquid. It will burn, skin will get red and peel off… But stuff usually falls off after several applications. However, if you’re talking about basal carcinoma, just go to the dermatologist and have it surgically removed. You don’t want to leave any residue and having a histological report of the cells is the way to go. My 2 cents!

  23. GB  February 6, 2015

    This is a study on warts where garlic killed 100% of warts. fat soluble work best.

  24. bigsnax  February 13, 2015

    I have chronic Gout, with very large Tophi. Is there a particular mixture of MSM, & DMSO that I should use to help with these typically?

  25. Gary  February 15, 2015

    I have a 12-1/2 year old Daushound , Her thyroid and immunity system went wrong and she has a severe enlarge lymph glands. I had her thyroid checked and she was deficient, now taking Thyrovet, L-Thyroxine,0.2 twice a day. She is better but doesn’t have much energy and has a reicuring tear duct infection in one eye. The proscribed salves didn’t help so I am able to clear it up each time with a weak MMS (chlorine dioxide) I give he two spoons of Alpo mixed with natural (no wheat)dry and a two table spoons of natural yeast, afew drops of natural coloridal minerals and a couple of drops of very diluted Lugos iodine solution, hopeing it will help her thyroid. I take DMSO every day ( the only thing that clears my nose. Could DMSO help her and is there a safe dose for a topical application so it won’t harm her?
    Thanks in Advance Gary

    • Gabriela Segura, MD  February 16, 2015

      The advice in this post and its comments would be helpful:

      You can experiment with a 15-20% dilution to see if it helps. Best!

      • Gary  April 14, 2015

        I wroe eariler about my 12-1/2 year old daushound having to take thyroid. Inow have her on that scotish diet you recomended. I’m writing about findind a natural detox program which would clan all of the crud in her liver and other organs. thank you for giving much valueable advice

      • Gabriela Segura, MD  April 14, 2015

        Good to hear about the diet. It is really the most important thing, the rest is complementary and it can vary upon preference. There is alpha lipoic acid which has been used on some pets. That would be an interesting line of research for liver detox. Best.

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