DMSO: The Real Miracle Solution

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Due to the nuclear alert in Japan and its likelihood to affect the United States and other parts of the world, I decided to carry this article which I wrote for the Dot Connector Magazine‘s issue N. 12.

First, a little bit of background.

Radiation produces free-radicals (“inflammatory molecules”) that damage cells that make up tissues such as organs, glands, muscles, and bones. Besides causing the cells to age more quickly they also become distorted, or mutated, creating cancers such as leukemia, anemia, birth defects, and other diseases.

Sulfur has a long history of use as an antidote for acute exposure to radioactive material. DMSO is the classical sulfur compound. A Japanese study showed that even low concentrations of DMSO had radio-protective effects through the facilitation of DNA double-strand break repair, providing protection against radiation damage at all cellular levels in the whole body.

Remember that boosting your body’s detox capabilities and overall anti-oxidants levels is a key to survive in these stressful times. Being on a detox diet is crucial to regain health in a toxic environment. Our extensive experience and research shows that those on a no grain/low carb (no gluten) and non dairy diet fare MUCH better.

For more information on how to protect yourself from nuclear radiation, see:

Treatments for Nuclear Contamination

Iodine Treatments for Radiation Exposure – Radioprotective

DMSO is an effective pain killer, blocking nerve conduction fibers that produce pain. It reduces inflammation and swelling by reducing inflammatory chemicals. It improves blood supply to an area of injury by dilating blood vessels and increasing delivery of oxygen and by reducing blood platelet stickiness. It stimulates healing, which is a key to its usefulness in any condition. It is among the most potent free radical scavengers known to man, if not the most potent one.

In 1866, Russian scientist Alexander Saytzeff isolated a most curious and peculiar chemical compound. It was crystalline, odor-less, non-toxic and had a garlic-like taste when consumed. At the time, Saytzeff had no way to predict that his discovery was going to prove highly controversial throughout its entire medical history, that it was going to be tested in thousands of studies, providing miraculous relief in numerous patients.

I’m talking here about dimethyl sulfoxide (DMSO), an organic sulfur compound which was used only as an industrial solvent, that is, until its medical properties were discovered in 1963 by a research team headed by Stanley W. Jacob, MD.
DMSO is a by-product of kraft pulping (the “sulfate process”) which converts wood into wood pulp consisting of almost pure cellulose fibers. As industrial as it may sound, the process simply entails a treatment of wood chips with a mixture of sodium hydroxide and sodium sulfide, known as white liquor, breaking the bonds which link lignin (from the Latin word lignum, meaning wood) to the cellulose.

DMSO is useful as a pain reliever, in burns, acne, arthritis, mental retardation, strokes, amyloidosis, head injury, scleroderma, it soothes toothaches, eases headaches, hemorroids, muscle strains, it prevents paralysis from spinal-chord injuries, it softens scar tissues. In fact, it is useful in well over 300 ailments and it is safe to use. You would think that a compound that has so many alleged uses and benefits will be automatically suspect, but careful examination of its properties and the data available will shed some light in this miraculous chemical.

Sulfur: The Stuff of Life

DMSO is an intermediate product of the global Sulfur Cycle which distributes bioavailable sulfur for all animal and plant life (Parcell, 2002). Sulfur compounds are found in all body cells and are indispensable for life, they are needed for a number of chemical reactions involved in the detoxification of drugs and other harmful toxins, and they have potential clinical applications in the treatment of a number of conditions such as depression, fibromyalgia, arthritis, intersticial cystitis, athletic injuries, congestive heart failure, diabetes, cancer, and AIDS (Parcell, 2002). Among the sulfur compounds, DMSO is probably the one that has the widest range and greatest number of therapeutic applications ever shown for any other single chemical. It has around 40 pharmacological properties that may be beneficial in the prevention, relief or reversal of numerous diseases (Morton, 1993).

Someone complained to Dr. Jacob of a splitting headache and gave him permission to apply some DMSO after hearing of its capabilities. The headache was gone in minutes, came back in four hours, and left for good after DMSO was applied a second time. Used for one purpose, sometimes it did another; put on a cold sore, within a few hours it cleared up a woman’s sinusitis. A woman who had had a stroke found after DMSO was painted on her painful jaw that she could now write with her paralyzed hand and could walk better. (Haley, 2000)

Therapeutic Properties

DMSO is an effective pain killer, blocking nerve conduction fibers that produce pain. It reduces inflammation and swelling by reducing inflammatory chemicals. It improves blood supply to an area of injury by dilating blood vessels and increasing delivery of oxygen and by reducing blood platelet stickiness. It stimulates healing, which is a key to its usefulness in any condition. It is among the most potent free radical scavengers known to man, if not the most potent one. This is a crucial mechanism since some molecules in our bodies produce an unequal number of electrons and the instability of the number causes them to destroy other cells. DMSO hooks on to those molecules and they are then expelled from the body with the DMSO.



DMSO also penetrates the skin and the blood-brain barrier with ease, penetrating tissues, and entering the bloodstream. Furthermore, DMSO protects the cells from mechanical damage and less of it is needed to achieve results as time passes as oppossed to most pharmaceuticals where increasing doses are required. It has a calming effect in the central nervous system and it reaches all areas of the body, when absorbed through the skin, including the brain. That is, DMSO applied to one area often leads to pain relief in some other location due to its systemic effect.

It acts as a carrier for other substances or drugs and it also potentiates their effect. In fact, certain drugs dissolved in DMSO, such as corticoids, antibiotics and insulin, may be used in a lower dose than usual without reducing their therapeutic efficacy and in addition, their undesirable side effects are greatly diminished. Also, drugs are able to pass through the blood-brain barrier which is usually impenetrable.

DMSO promotes the excretion of urine and functions as a muscle relaxant. It boosts the immune system, increasing the production of white cells and macrophages that destroy foreign material and pathogens in the body. It also has anti-bacterial, anti-viral and anti-fungal properties. DMSO also increases the permeability of cell membranes, allowing a flushing of toxins from the cell.

DMSO has radioprotective properties against lethal and mutagenic effects of X-rays in cells, cellular systems and whole animals. It also has cryoprotective properties, meaning that it is capable of protecting against injury due to freezing.
DMSO has also been shown to have anti-cholinesterase properties (Sams, 1967), in other words, it inhibits an enzyme from breaking down acetylcholine, increasing both the level and duration of action of this important neurotransmitter. Acetylcholine is responsible for learning and memory and is also calming and relaxing. Acetylcholine is also a major factor in regulating the immune system, acting as a major brake on inflammation in the body.

As a source of sulfur, DMSO aids in heavy metal detoxification. Sulfur binds with toxic heavy metals (mercury, lead, aluminum, cadmium, arsenic, nickel) and eliminates them via urination, defecation and sweating.

FDA and Big Pharma Obstacles

DMSO is sold in health food stores, mail-order outlets, on the Internet, and in most countries around the world. It is used by millions for its health benefits yet in the U.S., DMSO has FDA approval only as a preservative of stem cells, bone marrow cells, and organs for transplant, and for interstitial cystitis – a painful inflammatory condition of the bladder which is very difficult to treat with other therapies.

That DMSO has not found favor as a remedy for other medical conditions is partly due to the inability to test it in double-blind experiments. Blind studies, as the name suggests, requires that a study be done without knowing which patient is taking the placebo or the drug. In the case of the DMSO, a blind study is impossible since the peculiar garlic-like taste and smell (no matter the route of application) gives it away and no satisfactory placebo could be devised that would mimic this particular effect of DMSO (Steinberg, 1967).

The FDA and big pharma would prefer we remain dependent on their drugs.

If you search for DMSO on the U.S. National Library of Medicine (, you’ll get almost 30,000 indexed results, making it one of the most studied compounds of our time. Yet, we are led to believe that DMSO can’t pass the required regulations for its approval in other medical conditions even though its effectiveness and low toxicity profile is unquestionable.

You see, DMSO is a common chemical that can be manufactured cheaply. No drug company can get an exclusive patent since it is also a natural compound, therefore there is no significant financial return. In fact, an executive of a major drug company is quoted as saying, “I don’t care if DMSO is the major drug of our century and we all know it is, it isn’t worth it to us” [CBS TV show 60 minutes with Mike Wallace, The Riddle of DMSO]. If DMSO were to be approved by the FDA, it would be competetive and drug companies would be unable to hold the patents. In the words of the director of the Bureau of Drugs of the FDA, J. Richard Crout, M.D., “DMSO is a low toxicity and safe compound (…) I think that it is a fact of life that drug companies are not going to invest in something unless they think there is some financial return” [CBS TV show 60 minutes with Mike Wallace, The Riddle of DMSO].

Despite restrictions on the use of DMSO, thousands of Americans purchase it on the ‘black market’ each year, its popularity due not to publicity, but rather ‘word of mouth’. When you have something that relieves all kinds of ailments, including some life-threatening ones, people naturally recommend it to friends and family!

In Perspective

In the 1960s, research with DMSO on humans was temporarily halted after certain animals treated with DMSO were found to have changes in the eye lens. Some of these changes resembled those seen in aging dogs (Gordon, 1967), but nevertheless, research was gradually restarted after no evidence was found of eye changes in humans. As Daniel Haley reports in his book Politics in Healing: “Tests in rabbits, dogs, and pigs (but not humans) had shown some problems. When quantities of DMSO equal to about ten times the maximum human dose were given every day over a period of six months, slight changes in the lenses of the animals’ eyes would result, enough to produce a slight nearsightedness. The lens changes were not enough to cause dogs difficulty when running – they didn’t bump into things – and in some cases, the changes disappeared after the massive DMSO doses were stopped. In no test at that time or since has DMSO ever caused cataracts, either in animals or in humans” (Haley, 2000).

In fact, DMSO is effective for macular degeneration and retinal disease, both diseases of the eye. This effectiveness was first discovered when patients with retinitis pigmentosa, a retinal disease, were taking DMSO for certain musculoskeleteal disorders. They sensed that their vision had improved and some had remarkable results (Morton, 1993).

As far as eyes are concerned, the evidence on DMSO is quite to the contrary. When several patients treated with DMSO for muscular problems reported to Dr. Jacob that their vision had improved, he sent them to Dr. Robert O. Hill, ophthalmologist at the University of Oregon Medical School. Confirming the favorable changes, Dr. Hill began his own experiments with DMSO (after it was known that the lens changes did not happen in humans). His research showed drops of 50% DMSO to be effective in retinitis pigmentosa and macular degeneration, and presented a report on this at the New York Academy of Sciences symposium in 1971. (Haley, 2000)

In contrast, the number of medication-related deaths in the U.S. is estimated at over 200,000 a year, making medications the third or fourth leading cause of death (Pezzalla, 2005). Even common pain relievers called NSAIDs, examples of which include Advil, Motrin, Aleve and aspirin, account for an estimated 7,600 deaths and 76,000 hospitalizations in the U.S. every year (Tamblyn et al, 1997). Taking this into consideration, it is safe to declare that DMSO is among the safest substances in the world today. In fact, the classic test for toxicity -the LD-50 test – measures the lethal dose (LD) at which half of a group of test animals is killed. The LD-50 tests for aspirin and DMSO show that aspirin is seven times more toxic than DMSO (Haley, 2000).

Quick Guide and Ailments

DMSO is generally applied to the skin in a gel, cream, or liquid. It can be taken by mouth or as an intravenous injection, in many cases along with other drugs. It has also been administered subcutaneously, intramuscularly, intraperitoneally, intrathecally, by inhalation, instilled into the eye, on the mucous membranes, and into the urinary bladder. Strenghs and dosages vary widely.
If you are just dealing with pain or an injury, use a topical application. Don’t drink it. Drinking it is for serious detoxing and other internal necessities. If you use a rose scented DMSO cream, chances are that nobody will be able to smell DMSO’s garlic-like smell.

DMSO being distilled.


The usual oral dose of DMSO is one teaspoon per day of DMSO 70% (Morton, 1993). But since it can trigger detoxification reactions and DMSO’s total excretion from the body can take several days, it is best to do it only once a week. Start with half a teaspoon of DMSO 50% and increase to a teaspoon of DMSO 70% only if any possible detoxification reaction is well tolerated.

When you use liquid DMSO in the skin, let it dry for over 20 to 30 minutes before wiping the rest out. The skin must be clean, dry, and unbroken for any topical use of DMSO. The face and the neck are more sensitive to DMSO and no higher concenrations than 50% should be applied there. Topical concentrations of DMSO should be kept below 70% in areas where there is a reduction of circulation. When 60 to 90% DMSO is applied to the skin, warmth, redness, itching, and somtimes local hives may occur. This usually disappears within a couple of hours and using natural aloe vera, gel or cream, will help counteract or prevent this effect. When 60 to 90% DMSO is applied to the palm on the hand, the skin may wrinkle and stay that way for several days.

“My brother put some DMSO gel (70% dmso, 30% aloe vera) on his shoulders and lower part of neck because he had muscle pain/soreness in that area, and it caused skin redness/irritation for a few hours, although it did diminish the muscle soreness as well…my grandma has rheumatoid arthritis that made her legs swell up and hurt continuously, and I had her apply the same DMSO gel, and after about 2-3 days of applying it once a day, the swelling was 90% gone, and I think within 4-5 days it was 100% gone, and she said the pain diminished as well.” – Michael Shatskiy, Los Angeles, California, United States

Chronic pain patients often have to apply the substance for 6 weeks before a change occurs, but many report relief to a degree that had not been able to obtain from any other source. In general, the greater the chronicity of the disorder, the longer the treatment with DMSO must be employed in order to achieve palliation (Steinberg , 1967).

Common health problems for which people will apply topical DMSO at home include acute musculoskeletal injuries and inflammations. The earlier DMSO is used, the more dramatic the result. A 70% concentration of DMSO mixed with water in volumes ranging from 8 to 12 ml, applied on and around the injury in a wide area at least three times daily, will have a healing affect in 4 out ot 5 people.

Arthritis, Sprains, Strains

It provides rapid amelioriation of pain and increased mobility and reduction of inflammation when used topically. You can see a positive response within 5 to 20 minutes and usually lasting for 4 to 6 hours. (Steinberg, 1967).

“Applying DMSO where it hurt to a six-year-old wasted from rheumatoid arthritis, in a half hour the child could move her shoulder and turn her head for the first time in two years. Persuaded to try walking, she managed a few steps and then burst into tears. “Why are you crying?” Dr Jacob asked her. “Because it doesn’t hurt anymore”, she replied. (Haley, 2000)

“My brother has arthritis of the spine. He is in pain and bedridden more than half the time. When he is treated with DMSO, he is able to lead a normal, active life… Just one application of this cheap, safe DMSO changed my brother from a grimacing patient into an active, pain-free man in exactly 30 minutes!” (Haley, 2000)

June Jones, once quarterback and later coach of the Atlanta Falcons pro-football team, had a bursitis calcification in his right shoulder. His career almost didn’t happen as he could hardly lift his arm, let alone throw a football. But he was aware of DMSO and had used DMSO for sprains, like thousands of others. He received a shot of DMSO in the shoulder and after using DMSO for 30 days straight, the calcification disappeared. (Haley, 2000)


Given soon after a stroke, DMSO can dissolve the clot that causes the stroke, restoring circulation and avoiding paralysis. Once DMSO gets into the body either daubed on the skin, given in I.V., or by mouth, it permeates the body and crosses the brain barrier, so even taken orally it can improve circulation. Ideally it should be I.V.

DMSO products

DMSO is available in various formats.


Even though DMSO 40% causes a prolongation of bleeding time, it is still indicated for use in treating embolic or hemorrhagic stroke. DMSO is superior to any other treatment for wounds to the brain where a great deal of bleeding is present (Morton, 1993).

One man who had a stroke at 7:30 AM refused to go to the hospital until after his wife had spoken with Dr. Stanley Jacob, which didn’t happen until 6:30 PM. Starting at 7 PM the day of the stroke, she gave him one ounce of 50% DMSO in a little orange juice every 15 minutes for two hours and then every half hour for two hours. The next day, her husband was better and soon returned to normal. A substance that can stop a stroke as it’s happening is something many might want in their home medicine chest .(Haley, 2000)

Angina, Heart Attacks, Injuries of the Brain and Spinal Chord

DMSO may help neutralize harmful effects on the heart and brain in medical disorders involving the head and spinal chord injury, stroke, memory dysfunction, and ischemic heart disease (Jacob, de la Torre, 2009). A 40% DMSO solution should be administered within four hours to be effective, within ninety minutes is best.

After I.V. administration of DMSO, there is an elevation in the amount of spinal cord blood flow to the region of trauma. One of the first things that happens after spinal cord trauma is that a reduction of oxygen and blood flow sets in, inasmuch as the blood vessels constrict or shut down… Without some treatment, the tissue swells. Eventually, this leads to paralysis. In a cerebral stroke, the animal will either become comatose or lethargic or die. With DMSO infusion immediately after injury (or stroke) all this is prevented. – Dr. Jack de Ia Torre, professor of physiology and neurosurgery at the University of New Mexico

Dr. Stanley Jacob has even given DMSO intravenously to people who were already paralyzed – paraplegics – and some regained use of limbs. One man, quadraplegic, recovered enough to go through college and then to work in a bank. (Haley, 2000)


When combined with antibiotics, DMSO will convert bacteria which are resistant to a given antibiotic to being sensitive to that same antibiotic and probably a 80 to 90 per cent solution of DMSO will be required in order to be clinically useful ( Pottz, Rampey, Benjamin,1967). DMSO has been used to transport antibiotics to hard-to-reach areas of the body with excellent results, such as the bone marrow and brain (Sanders, 1967).

DMSO can dissolve a virus protein coating, leaving the virus core unprotected with its nucleic acid exposed to the immune system. Applied topically, it alleviates the lesions that occur as a result of Herpes Zoster, shingles (Morton, 1993).
Placed into the nostrils or topically in the face, DMSO can open blocked sinuses within a few minutes and it has been used with sucess in patients with polyps (Marvin, 1967).

DMSO can clear up gum disease and reduce tooth decay and their pain by painting it on the involved areas.

“I have some pharmaceutical grade DMSO and I pour about two teaspoons in a glass in the evening, put my 20 mg of doxycycline in it, add about 2 teaspoons of distilled water, and then swish it around in my mouth for about 2 or 3 minutes and then swallow it. So I guess it is about 50% solution. It’s really working on my mouth. That inflamed area of my jaw has calmed down about 70% in just a couple of days. Or more, actually. I expect it to be completely soothed by tomorrow after tonight’s dose of DMSO.” – Laura, Toulouse, France

Keloids, Scars, Burns, Bruises

A concentration of 50 to 80% put on two or three times a day will flatten a raised scar after several months. It is of considerable value in superficial burns (Goldman, 1967) and when applied quickly to an injury, it can eliminate any bruising.

“I have been applying it to my face for two weeks… I had a bout of acne in March, and this healed the damage pretty well but what amazed me is that my hyperpigmentation (melasma) has also faded very noticeably. In fact, it’s amazing!” – HG, United States

“I diluted a 50% solution and applied it topically to the inflamed lymph node. I applied it again this evening. I am totally amazed! There is a noticeable decrease in the size of the node, in just two applications! And it no longer feels matted. This node has been swollen for over 20 years!!! – Melissa Medlock, Coldwater, Michigan, USA


DMSO can be effective in the treatment of painful corns, calluses, ingrown toenails, bunions, hammertoes, heel spurs, and the inflammation of gouty big toes.

Varicose veins and thrombophlebitis

Topical DMSO can whiten telangiectasias, small dilated blood vessels near the surface of the skin. It can also decrease the size of varicosities in the legs and the inflammation that goes with it, along with a relief of their cramping discomfort (Marvin, 1967. Blumenthal, Fuchs, 1967).

Eye problems

One drop of a 25% DMSO solution (diluted in sterile physiologic or saline solution) once or twice per day is useful for eye problems, including cataracts or glaucoma.

“DMSO is amazing, I’ve also read various good results with using it in the eyes. Being the adventurous type myself, today I diluted DMSO down to 30% and put 2 drops in one of my eyes that has been having red spots around the iris. The red spots diminished drastically. The only side effect was a slight burning sensation, similar to those drops you get when one goes for a glaucoma test, without the side effect of dilated pupils.” – DZ, United States


DMSO is highly effective in vascular headaches and in muscular tension which so often goes with headaches. It may be used on hairy areas such as the scalp and it also may be used near the eyes. A 90% solution is more effective (Ogden, 1967).

Mental Disorders

DMSO has been useful in the treatment of patients with the following diagnoses: (1) overexcited states (acute schizophrenic reactions, manic phase of the manic-depressive psychoses, alcoholic psychoses, symptomatic psychoses); (2) some symptoms of the chronic psychoses (autism, stereotypia, negativism, abnormal behavior or delusional states) ; (3) severe neuroses (anxiety reactions, obsessives)( Ramírez, Luza, 1967).

McGrady called special attention to an extraordinary paper presented by Dr. Eduardo Ramirez and Dr. Segisfredo Luza of the Ayetano Heredia University in Lima, Peru. After extensive tests on animals and then on normal humans, Dr. Ramirez reported “injecting 50% or 80% DMSO intramuscularly into patients with acute and chronic schizophrenia” and that “of the 14 acute cases, every single one was discharged from the hospital within 45 days after the start of DMSO treatment… He said that 4 of the 11 chronic cases, one of whom has been ill for 14 years, were discharged eventually, and the other 7 improved a great deal and were given occupational therapy… He observed rapid decrease in agitation… recession of persecution feeling, a relatively sudden tendency to communicate and to stay clean.., the wane of obsessions, return to alertness, and a calmness where there had been restlessness and anxiety”. (Haley, 2000)

Genitourinary disorders

DMSO has been used in the treatment of a number of patients with various genitourinary disorders, including Peyronie’s disease, interstitial cystitis, acute epididymitis. Some have obtained dramatic and gratifying relief of symptoms (Persky, Steeart, 1967).


DMSO in conjunction with other treatments has shown to regress cancer in a very effective way (Ayre, 1967). Intravenous administration of DMSO markedly reduces pathological intestinal permeability while preserving the gut’s absorption capacities (Wang et al, 1996). Considering that gut permeability (‘leaky gut’) has a fundamental role in chronic degenerative diseases, this is of great clinical importance.

DMSO also has excellent results in the skin of people afflicted with scleroderma, results which have never been observed with any other method of therapy (Scherbel et al, 1967).

Mrs. Jean Puccio of Washington, DC testified at hearings of Senator Edward Kennedy’s sub-committee on health in 1980 on her recovery from scleroderma. Diagnosed in 1971, she was told that no medication would help, and that she would probably soon face a wheelchair and early death. By the time she found Dr. Jacob (through word of mouth), she told the Senators, “I was having difficulty breathing, walking, and eating”. The disease “thickens the tissue and makes your skin so tight you cannot move. It was difficult for me to drive, to turn the ignition in my car or turn my body”. Her dentist could not work on her for awhile because she could not open her mouth. “Now I can open my mouth like anybody”, she said. After her sensitized skin burned from topical application of DMSO, Dr. Jacob suggested taking it orally. “Within six months”, she testified, “my condition reversed almost immediately. I can do anything anybody else can do now” (Haley, 2000).

Hopefully, this brief overview of DMSO’s great capabilities has helped to illustrate how it is indeed, the cure of our times. I’m convinced of its therapeutic power, both by my own experience and that one of scores of people, not to mention the back-up of published scientific literature. Its uses and applications make it a very handy compound to have on your medical shelf. In pure form, the life of DMSO is indefinite, so it may be used for years.


Several books have been published on the benefits of DMSO.



The garlic-like body odor and taste in the mouth that some experience is attributable to a specific DMSO metabolite: dimethyl sulfide (DMS), a component of natural onion and garlic flavors (McKim, Strub, 2008). This can last for one or two days and in a small number of people, especially men, the odor can be very pungent. Drinking enough water will help diffuse the smell. Other side effects – such as stomach upset, headaches, dizziness, and sedation – are very likely related to detoxification reactions prompted by the DMSO.

Only purified and properly diluted DMSO should be used. When you dilute a pure DMSO solution, always do it in distilled water. When it is applied, the skin site as well as the applying hand should be thoroughly cleaned before application. This is of utmost importance as DMSO’s properties allow contaminants to be absorbed through the skin and transported into the bloodstream.
DMSO is known to be one of the least toxic substances in biology (Parcell, 2002), so any serious side effects should come from potential contaminants or the intake of concomintant drugs that DMSO will carry into the body. Worth repeating again, DMSO and any substance dissolved in it, will penetrate the skin, the blood-brain barrier, and other parts of the body very fast.

Remember also that DMSO increases the effects of drugs like blood thinners, steroids, heart medicines, sedatives, etc. In addition to that, acetone or acid contamination of DMSO can lead to serious medical consequences. Be aware of this problem when buying unreliable DMSO. A pure DMSO solution will turn solid (like ice) in the refigerator within 2 hours. If, when the frozen bottle is turned upside down, little rivulets of water flow through the ice, you probably possess the veterinary grade DMSO. This is a 90% concentration. Ten percent is distilled water (Morton, 1993).

Women are discouraged from using DMSO during pregnancy or breastfeeding, even though DMSO is used to preserve frozen human embryos. DMSO can interfere with liver function tests and give a false reading. That problem is easily solved by waiting a week after DMSO usage before taking the test.

Long-term use has been documented as safe. Eye damage, reported in laboratory animals, has not been confirmed. Side effects such as skin rash and itching after topical application, breaking up of blood elements after intravenous infusion, can be avoided in large part by employing more dilute solutions. Despite these side effects, DMSO is used as a preservative for blood elements and stem cells (McKim, Strub, 2008).

When DMSO is diluted with water, heat is released. The bottle will be warm to the touch. This is a temporary, harmless reaction.
Since DMSO causes dryness and scaling of the outer layer of the skin, skin diseases characterized by scaling (psoriasis) could be aggravated by the use of DMSO. But DMSO applied topically for only a few days has been useful in psoriasis. Prolonged use of DMSO for the treatment of psoriasis is not advised however, as it can worsen the psoriatic condition (Engel, 1967), only DMSO taken orally is suggested.

“I’m happy to say that taking DMSO in conjunction with implementing the detoxification suggestions that were given is starting to take care of many of my remaining psoriasis problems. A couple areas are still being stubborn, but I’ve noticed a lot of general improvement. Using DMSO topically also helped improve a patch of eczema that my wife has been bothered by for quite a while.” – Peter Norquest, Tucson, Arizona, United States

DMSO2, a derivative of DMSO, is better tolerated and doesn’t have the odor and irritation side effects. Despite this positive aspect, it hasn’t surpassed the effectiveness, fascination and popularity of DMSO. It is also known as methylsufonlmethane or MSM, an entire topic for another article by itself!

Sulfur is an element of the earth and it is essential to life, it as among the most prevalent elemenents in the human body. Allergic reactions to sulfur are not possible because sulfur has no protein component. When people are ‘allergic to sulfur’, what they really mean is that they are allergic or sensitive mainly to certain sulfur-containing drugs or proteins, most notably sulfa antibiotics (sulfonamides) or to sulfites (preservatives used in wines and some foods), or to foods with a high sulfur content (broccoli, cauliflower, garlic, onions, etc). Many individuals with allergies to sulfa drugs, sulfites, or high sulfur containing foods (like the author) do not experience problems taking DMSO, because apart from sulfur, DMSO bears no relation to these substances.

As always, proceed with caution, do your homework, and consult a health care provider in case of doubts.


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  1. Irene Werner  August 1, 2019

    Can DMSO harm the intestinal flora? I plan to take 3 table spoons per day for a prolonged time.

    • Richy  August 2, 2019

      FWIK, THIS IS A HARMFUL DOSE…Even people with much experience with DMSO rarely ever take more than 1-TEASPOON per day. And THEN only a 50% solution.
      You will most-probably wind-up in the ER.
      Just DON’T…This is what keeps meds “prescription only”.
      People get a wild-hair to do something that can maim or kill.
      If you’ve already tried this, I’m sorry. You will be also.

    • Elaine Vickery  June 23, 2021

      I just bought DMSO in both the liquid form (99%) and a gel form (also 99%). I haven’t yet tried DMSO at all. It says on the two containers which are plastic, “Not approved for human use. After rereading the article, “DMSO: The Real Miracle Solution/ The Health Matrix,” I am not sure whether to use it or not. I am not sure how to dilute it nor how to take it internally or apply it to my skin. Can you make suggestions to me? I have several autoimmune conditions including Scleroderma (both internal and external form), Reynauds, Sjogrens and active Epstein Barr Virus.
      For example, how should I dilute the gel to apply topically and how should I dilute the 99% pure DMSO liquid?
      Thank you for the informative article.

      • Mark Butler  June 23, 2021

        The 99% grade is usually labeled for Veterinarian use but I and many others have used it without problems. If is turns to a solid in your fridge with just a few drops of liquid then it is manly pure DSMO. If you use it on your skin you should dilute it with distilled water at 70% DMSO. I suggest you read one of the books on DMSO. Two I like are The DMSO Handbook for Doctors by Archie H. Scott and Dr. Morton’s book Dmso: Nature’s Healer.

        I also have Raynaud’s and what I do is run some warm water over my hands then apply 100% DMSO and rub it in. I found a supplier that sells 99.99% pure DSMO and that’s what I’m getting now. There website is DMSO Canada.

  2. Mark Butler  August 23, 2019

    Has anyone had any experience using DMSO for wound healing. I have a deep cut in my foot about 15 cm long and had the stitches removed a week ago. I’m thinking of placing a piece of gauze soaked in a 70% solution of DSMO to speed up the healing and take away some of the swelling.

    • Richy  August 23, 2019

      Use colloidal silver solution…It makes other anti-infective/antibiotics look sad in comparison.
      We’re seniors, and we use it for any skin wounds. Even potential infections, ear problems, burns, cat scratches, whatever.
      I spray it in my eyes every day, it’s much more refreshing than anything else I’ve tried.
      Unfortunately, it doesn’t seem to work internally.
      I’ve had serious hand cuts heal almost overnight, better than in my twenties!
      Downside is argyria, which stains the skin gray. For those dumb-enough to make their own CS, and not smart-enough to filter the heavy silver solids first.
      Use it for ANY external condition.
      Buy the big blue bottles on Ebay or make your own with a simple battery/silver strip setup.
      DMSO is not to be used on open wounds. It will endeavor to shed and irritated the wound.

      • Mark Butler  August 23, 2019

        Thanks Richy. I I didn’t think about colloidal silver.

      • Chris  October 31, 2021

        HI. Don’t do the gauze trick. A friend did and it caused blisters. With any wounds I have had, I just rubbed DMSO around the outside of the wound area until the DMSO is soaked in. No need to over do it.

  3. Richy  August 23, 2019

    If you apply it and it stings a bit, that’s when it’s killing high levels of pathogens. But it’s not an antibiotic, it’s an anti-infective. Very different. ‘Anti-infective’ means that area cannot come under pathogenic colonization.
    Normally, you won’t feel a thing.
    Impossible to use too-much, as it just air dries invisibly.
    I’ve tried to tell veterinarians and animal healers about it online, as I see these terrible tales burned or wounded animals having to be euthanized unnecessarily.
    Just guessing here, but I can see an old, rough cowboy under great duress eating and drinking only beans, coffee, and hard-tack being beaten-up in the saddle. Someone had told him that “sucking on a silver coin would lessen your woes greatly”, and that’s where the CS legend began.

    • Mark Butler  August 24, 2019

      I feel like an old beat up cowboy at the moment and silver coins are hard to come by so I’ll try the colloidal silver!

      • Richy  August 24, 2019

        Yes, I use two old and greatly eroded Canadian dollars for my CS. (Bought when they were cheap.)
        I, too, am the “beat-up guy”…I thank God everyday that I DON’T have to suffer the saddle with my “significant spinal nerve root impingement”. Enough pain already, and Drs. scared to death of the CDC taking their licenses away.
        Different subject matter.

  4. Elaine  September 22, 2019

    Does anyone know if DMSO is safe to use topically (neck, shoulders) IF you possibly have heavy metal toxicity? I read it is sometimes used for heavy metal detox but I’m not wanting it for that just for pain. Don’t want it to possibly “redistribute” heavy metals by rubbing on my neck. Thanks!

    • Richy  September 25, 2019

      There are MANY possible causes for a sore neck, probably the least of which would be heavy metal poisoning.
      Sprains, overuse of a muscle group (lactic acid buildup), misaligned vertebra, tendon, ligament retraction, other toxins, stress elsewhere expressing itself,etc, etc…
      DMSO is very useful foe soreness as the increase in blood flow brings relief.
      The only thing to watch out for is skin shedding and terrible itching if one applies a strong solution and overdoes it.
      I use 30% +- in a small spray bottle a few times per day.
      I learned my lesson the hard way a few times and don’t want to revisit that scenario.

  5. lisa williams  October 26, 2019

    hi can someone please advise best place to purchase i did so from amazon uk in herbalcream i do not think it,s the real deal due to what i have actually read up on this miracle assistant thank u lisa uk

    • Mark Butler  October 27, 2019

      The last time I ordered I purchased from It is 99.99% pure and I liked that it came in a glass bottle.

      • Richy  October 30, 2019

        I don’t know how much you paid, but “odorless” 1-gallon DMSO is available on Ebay cheap.

  6. Coco  October 30, 2019

    Can I take Alieve if I used DMSO gel same day?

  7. Richy  October 30, 2019

    FWIK – External use of DMSO will have little-to-no effect on internally-used substances.

  8. Mark Butler  November 5, 2019

    I found a new use for DMSO that I want to share. I have a disease called raynaud’s that causes the blood vessels in my fingers to constrict when exposed to the cold. I have had this all my life and it limits what I can do outdoors in the winter because even heavy gloves and hand warmers don’t prevent it. My doctor told me 30 years ago there was nothing I could do to cure this.

    I was re-reading two books I have on DMSO (Archie Scott and Morton Walker) and it suddenly dawned on me that DMSO being a vasolator might help my raynaud’s. I have been working outside and it’s getting cold where I live so I rubbed some 70% DMSO on my hands before going outside. This is the first time I have been able to work outside like this without gloves and without heating my hands up in a bucket of hot water every 15 minutes! No more white tipped fingers.

    • Gabriela Segura, MD  November 5, 2019

      Great testimonial! Thanks for sharing!

    • Richy  November 5, 2019

      Outstanding! Good on you Mark!
      I might add that my wife has always had spider veins and dark bruising on her legs.
      Knowing that ascorbic acid (Vitamin C) would help with the collagen problems, I recommended that.
      Unfortunately, she reacts to even the slightest amount of C with diarrhea exactly as-if she had overdosed to bowel tolerance, go-figger!
      SO, I then recommended DMSO 30% (as to avoid skin irritation and sloughing) and *presto*, bruising, spider veins, and EVEN VARICOSE VEINS GONE!
      She hates the odor, even though this is the *odorless* type…So now she is averse on that reasoning..
      I told her to use it, let it penetrate and then wash or rinse off any excess.

      • Stephanie  March 17, 2020

        If she uses it while using a set of swimmer’s nose plugs, it will help. She can remove them within just a couple of minutes or so because, by then, the smell will have dissipated.
        I use the nose plug when taking my daily teaspoon of 70% DMSO in half a glass of water or juice daily. It has a truly vile bitter taste, even when diluted, and having the nose plugs on helps reduce the experience by a lot. I then take a piece of very sour candy in my mouth and work it into all the corners. That neutralizes the remaining taste still in my mouth. Then I remove the nose plug and spit out the remaining candy (or finish it, as the mood dictates…) :)

        Thanks to the author. Wonderful article! I have been using it as a reference page for anyone I want to introduce to DMSO.

      • Frank  June 27, 2021

        Hi Richy. Both my GF & my adult daughter take vit b12, which has eliminated the issue of bruising easily. I hope this info helps.

  9. Cassandra Wynne  November 16, 2019

    Can you use DMSO to treat puffy eye bags?
    Someone mentioned castor oil & DMSO mix…

  10. Sherie  December 19, 2019

    I came here looking for info on using it to clear a nasty sinus infection. I didn’t see any protocols for that so I’m trying the DMSO in a Neti pot with distilled water and an Xlear saline packet which is saline with xylitol added. Did the first one tonight with 1/2 a teaspoon of pure DMSO added to the 8oz bottle. Since I’m not drinking it just flushing thru I figured I’d start with that. I also did a flush with just the xlear first so my sinuses would be cleaned as much as possible first. There seems to be no bad effects interestingly my lips grew very deep in color after doing it like I had lip stick on! I feel a slight pulse in my face but that’s it. But does anyone on here have experience with using it for sinuses?

    • Chris  December 19, 2019

      This might sound odd. For the sniffles I put DMSO on my finger and stick it up my nose. No side effects other then I don’t get as sick as the people around me.

    • Debi  May 21, 2020

      The only thing I would be concerned about or want to know as well is if the pot was plastic other than glass?

  11. Richy  December 19, 2019

    Not too surprising as DMSO increases blood flow. Just keep in mind that 100% isn’t recommended and is actually weaker than diluted forms.
    You may have found a good remedy for allergic reactions also!

    • Chris  December 19, 2019

      I use the little, 4oz roll on bottle. Not ultra pure but it works on most ever scrap, scratch or blemish. Not so sure about this “ cut it down and it will work better” idea that has been floated here. Like saying “if you cut your paint by 50 % it will cover better”. Also if you rub it in it won’t sting as much. Leaving a dab on the surface of the skin will sting and turn the area red. And of course, if you stick it in your nose it will help
      the sniffles go away.

      • Richy  January 23, 2020

        DMSO reacts with H2O(water) as you’d see if you mixed i (gets hot).
        We here got our information from past research of pharma people and Drs who used it long before most of us were born. Cutting with water potentiates/activates it…Like the activor in epoxy.
        That being said, if you want to use it straight-up, “Don’t hold back if it feels good, do it”!

  12. Vivek Mehra  January 23, 2020

    Has anyone benefitted from DMSO in vitiligo/leucoderma the skin issue?

  13. Sherie Suter  January 23, 2020

    So this is an update using it in the netipot worked really well I did it morning and night for a few days I bumped it up to 1/2 a teaspoon in the mix with distilled water and an Xlear sinus packet and twice had pockets of egg yolk yellow come out that were really nasty and thick. The DMSO got it into the places the rinsing alone couldn’t and the Xlear broke down the biofilm I also took oil of oregano pills 4 morning and night. Doing this I cleared that horrible sinus infection without going on antibiotics!

    • Richy  January 24, 2020

      Good on you! A smart & brave person.
      Just watch it as I can testify it will cause skin sloughing (peeling), preceded by terrible itching.
      Lord only knows what resulting difficulties and how THAT would affect your sinuses!

  14. Jerome Keogh  January 25, 2020

    Hello folks – has anyone been burned by DMSO. About 3-4 months ago I liberally applied 99.4% undiluted DMSO on both my wrists for what was a minor ailment. Within a day or two I developed a red rash at the bottom of my wrists where my thumbs starts. It looks inflamed so I applied aloe vera gel, oil of oregano, coconut oil, honey and even colloidal silver at different times with little or no improvement. It doesn’t hurt but it gets extremely itchy and clothes touching the area or washing the area just seems to irritate it; plus it looks nasty. Any suggestions to get rid of this would be welcome. Thank you

  15. Richy  January 26, 2020

    “Undiluted DMSO” will burn and your skin will slough off..
    Not only is it a weaker solution than the diluted forms, it’s actually nasty to use..
    I have the “diabetic” thin skin on my lower legs..
    I used DMSO 30-40% spray and got tremendous itching afterward.
    I rubbed it gently with my fingers and the skin came right-off!
    So as I write this, I’m healing from the intense stabbing pain until it grows back.
    Abusing or even regular use can and will give you some nastygrams!

  16. Jason  April 13, 2020

    Great write up. I’ve been using dmso for my knee and shoulder. Love it.
    I have a quick question in regards to gynecomastia. I am a male and presently dealing with a lump on the sides on my nipples. Went to the doc and he said that gynecomastia was forming and suggested some medications to decrease the formation, but will affect my hormones (decrease estrogen levels). I’m tempted to apply dmso to the areas to possibly help eradicate the formation of the fat tissue behind and around my nipples, but thinking it may do the opposite since it does help with cell regeneration. Am I wrong? Any advice/suggestions are more than helpful.
    Thanks for your prompt replies


  17. Backinservice  October 6, 2020

    Can this be used in a nebulizer or essential oil diffuse with distilled water or would a nebulizerr be affected and pick up toxins?

    • Gabriela Segura, MD  October 7, 2020

      It can and has been used in nebulizer

      • Frank  June 27, 2021

        Hi Dr. Gaby

        I tried to post a question on this blog post regarding dmso & the healing of my fractured arm. Could you tell me please why it was deleted so that I don’t violate any rules in the future and/or how I might rephrase it so that my question would be allowed? Thank you very much for any help you can give with this. Note: I did try 1st. sending this to you on your contact page, but it wont go through.

      • Frank  June 28, 2021

        Seems like a bad idea. My concern would be that the dmso might dissolve the plastic or rubber parts… especially the tubing.

      • Anthony Thomas  October 3, 2021

        Can you supply any details as to dilution etc?


  18. Mr Richard Spurr  December 9, 2020

    Discovered DMSO looking for an alternative to Diclofenac/Tramadol for my ladies osteoarthritis pains. A 50% spray on her shoulder/arm worked a treat within 5 minutes. It works better mixed with an ampule of Diclofenac. Morton’s great book cited its use for Tinnitus which I have ( gentle hissing), so I tried it (50% spray). My Tinnitus may have improved a little, but it shifted all my ear wax and my hearing has improved by at least 60% in my left ear which has never been as good as my right one.

    • Bagrman  December 9, 2020

      Good day Mr. Spurr, Good to hear the DMSO is working for you and your wife. I recently found, The DMSO Handbook for Doctors. Lots of great info, quick easy read also. I am wondering what the name of Mortons book is that you make reference to? Thank you

      • Mr Richard Spurr  December 10, 2020

        The book is pictured on the website: DMSO Natures Healer by Dr Morton Walker.
        Great value at £13 on Ebay. The strange thing to me is that DMSO is used medicinally in Russia where my ladyfriend comes from yet she has never heard about it or had it offered as treatment for osteoarthritis.
        Enjoy your day…

  19. Ali  February 25, 2021

    On my second week of taking DMSO. The first week I took 1/2 tsp twice that week. This week I did two days at 1/2 and 1 tsp for the third day. The first time taking and the third day of the second week. I have felt pressure in my nose and ears. My ears were very clogged with the first dose. I do have nasal drainage about a hour after taking it. Can this be common and any ideas as to why? It does usually clear up.

  20. Chris  May 5, 2021

    Recently read, The DMSO Handbook for Doctors. Lots of good info in it, but what caught my interest was where it was noted to be and anti-inflammatory. Well my prostate is swollen so I experimented. Each morning for the last 4 months I have wet the end of my finger and applied it to the area just behind the scrotum below the prostate. 3 applications to an area about the size of a 50 cent piece. I do this after my shower or I just wash the area and dry it well. I’m sure to rub it in completely other wise it will sting. Results, Blood test at the end of December showed a PSA count of 4.17, one taken at the end of March showed a drop to 3.58. For the past 10 years at each physical there had been a steady increase.
    Results, Urine flow stronger, bladder being emptied far better. Happier in all categories. Best result is that I can sleep through the night. I am not a doctor so this is not a recommendations or prescription, just letting you know my experience.

    • Chris  June 12, 2021

      Protocal change: 2 dabs in the morning and two in the afternoon. That’s seems to work best for me> your results may vary.

    • Mark Butler  June 12, 2021

      Great testimonial!

  21. Frank  June 27, 2021

    Hi. I was recently in a motorcycle accident and would like to use dmso to speed healing & to protect from nerve damage. I’m pretty banged up, knee’s & elbows are swollen, have “road rash”, broken fingers, a dislocated wrist & a broken forearm/Galeazzi fracture. Had surgery 4 days ago and a steel (or titanium) plate plus screws installed in my forearm. Have a bolt in one of my fingers. Plus sutures in my forearm. I have a lot of experience w/dmso and do not need instruction on how to apply it. Would prefer to drink it but that wouldn’t be safe considering the meds I am taking.

    My concerns are:
    1. will it dissolve my sutures/stitches?
    2. poss drug interactions

    I am taking the following:
    2 percocet 5-325 for pain every 6hrs.
    promethazine for nausea
    augmentin 875-125mg 2x per day antibiotic
    naproxen 440mg 2x per day
    nexium 20mg 2x per day (because naproxen hurts my stomach)

    My question is “can I apply DMSO to my swollen, but otherwise undamaged knees?”

    Thank you.

  22. Frank  June 27, 2021

    Hi. Four days ago, I had surgery for a broken forearm/Galeazzi fracture in which a steel (or titanium) plate & screws were installed. I am also currently taking pain meds. I’m wondering if I can apply dmso to unaffected areas to speed healing & to help protect from nerve damage. Any thoughts on this would be greatly appreciated. thanks.

  23. Patricia  September 29, 2021

    Hi, I stepped on a nail 9 days ago that went through the sole of my shoe and going maybe about an eighth of an inch into my foot. Unfortunately I have not had my tetanus shot in the last 5 years and because the wound was so small and didn’t go deep I decided not to go get a shot at that time. It didn’t bleed much and I immediately cleaned it out with hydrogen Peroxide and made sure there was nothing stuck in the wound. I applied Neosporin to the wound and bandaged it up. On the fourth day I started applying DMSO to the wound. Now for the last 3 or 4 days I have started having mild muscle pains off and on throughout my body and also having a headache and neck pain when I first get up in the morning until I can get the DMSO on my neck and temples and forehead and it takes the pain away all day. My question is will the DMSO be able to get to the toxin and remove it or can the DMSO protect my Central Nervous System until the toxin run it’s course. I would be interested to hear if anyone has dealt with this kind of situation.

    • Mark Butler  September 30, 2021

      I would apply MMS then add some DMSO on top. The DMSO will carry the MMS into your foot and kill whatever pathogens exist. If you don’t have any MMS then any antibiotic applied will be much more effective with DMSO. I have had a few infections like yours and the MMS with DMSO worked almost instantly. Much faster than taking prescription antibiotics and much safer.

    • Stephanie  September 30, 2021

      You can buy a homeopathic remedy called “Hypericum perforatum”. Use the 30C potency.. Next time, if you have a puncture type wound, suggest you treat right away with “Ledum palustre 30C” This goes for all kinds of puncture woulds – nails, animal bites, insect bites, etc. in the early stages. Hypericum is for when tetanus may already have set in. Both are taken by mouth, taking care not to touch the pills with your hands.

  24. Anthony Thomas  October 3, 2021

    Hi. Has anyone got any advice about using DMSO to get rid of or reduce tinnitus?


    • Stephanie  October 3, 2021

      This helped me, but I don’t have a very bad case, It only comes up occasionally, but less and less often since I started following this technique. Perhaps it will help you too:

      • Anthony Thomas  October 31, 2021

        Thanks Stephanie,

        I have tried that technique with no real results. I am learning to live with it to be honest.


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