Heal Thyself with Homemade Liposomal Vitamin C

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“In fact even when there is not a single outward symptom of trouble, a person may be in a state of vitamin C deficiency more dangerous than scurvy itself. When such a condition is not detected, and continues uncorrected, the teeth and bones will be damaged, and what may be even more serious, the blood stream is weakened to the point where it can no longer resist or fight infections not so easily cured as scurvy.” –Food and Life Yearbook 1939, U.S. Department of Agriculture.

Vitamin C has been a long-time favorite supplement for many and for very good reasons. It is the one thing that has made the whole difference for detox purposes, but it has also saved the lives of many around the world. It has regained popularity recently as a DNA protector from free radical damage in workers with severe radiation exposure at the Fukushima nuclear plant, where workers had no significant change in both free DNA and overall cancer risk when supplemented with vitamin C.

Vitamin C also helps manufacture collagen, vital for the health of all our tissues and the repair of blood vessels, teeth, joints and bones. It also helps to normalize blood pressure, heal degenerative diseases and prevent premature aging. It is vital so our immune system can fight viruses, bacteria and other microbes. Vitamin C is also important in the synthesis of brain chemicals such as our happy mood neurotransmitter – serotonin.

Megadose Vitamin C


Nobel Prize winner, Linus Pauling and Dr. Irwin Stone have helped pioneer the concept of orthomolecular medicine which uses megadose vitamin therapy – vitamin C in doses higher than those required for normal cellular functions. When taken in very high doses (10 or 100 grams or more per day, depending upon the person’s requirements and illness) vitamin C fights off serious illness. For instance, when the body is challenged by cancer, colds, toxicity or diseases, we are overwhelmed with free radical production. This is when our requirements of vitamin C increases. Read about Vitamin C’s Historical and Miraculous Record.

Mainstream medicine remains in the dark when it comes to knowledge about vitamin C despite the miraculous effects it has had on people whose prognosis was fatal. Vitamin C or ascorbic acid, is something you want to have in your medical cabinet, as it can save your life as it had done so for so  many people around the world. Vitamin C is also the best thing so far for adrenal support during very stressful times and/or when we feel extremely fatigued.

As a powerful water-soluble anti-oxidant that we are not capable to synthesize within our bodies, you might want to take 1 heaping teaspoon (4 grams) per day, when you first start detoxifying. During stressful times (either emotional or from illness) more doses are required, especially when you are eating a diet rich in carbs.

As it happens, vitamin C and sugar use the same port entry to access our cells and when there is little to no sugar to compete, a higher percentage of vitamin C gets into the cells making our requirements shrink. This is why our need for vitamin C goes down to the point where most people had to minimize or even eliminate it in a ketogenic diet – a diet based on animal foods and fats. And since most animals make their own vitamin C, it is possible to get enough vitamin C in a ketogenic diet without any plant foods by eating the proper parts of the animal: organs.

Keep in mind that vitamin C dosage should be built up gradually, and the same is also true for lowering the dose of vitamin C, in order for our bodies to adjust to the change. Going slowly also prevents Herxheimer reactions which come when you first start detoxifying. A Herxheimer reaction is an excretion of toxins from dying microbes (i.e. yeast overgrowth), sometimes called a ‘die off’ reaction.

Some say that pregnant women should not exceed 5 grams of vitamin C a day, although early pioneers on vitamin C have used very large doses for the benefit of both the mother and the baby. Large doses can cause diarrhea since excess vitamin C than your body requires doesn’t get absorbed. In time of illness, you can gradually increase vitamin C by 2 to 4 grams each hour until your tummy starts to gargle or you have a loose stool. This is what is known as titrating doses of vitamin C.

The most inexpensive vitamin C is ascorbic acid which you can get in bulk size, although other high quality forms and alkaline and better absorbed versions are available such as sodium ascorbate. If ascorbic acid gives you acidity, mix with some stevia, xylitol or a little bit of sodium bicarbonate to take the bite off.

For those concerned that vitamin C will increase their blood sugar levels, well, it seems that it doesn’t, even at doses of 2 grams every 3 hours.

Unfortunately, with so many medical regulations and drug protocols, vitamin C’s healing effects has remained in the back stage in a system ruled by Big Pharma. Despite this, it continues to help many around the world and it is starting to regain increasing popularity in conditions where no drug has made such a difference as vitamin C does.

Nowadays there are options that can substitute the intravenous (IV) vitamin C therapy in megadoses in the form of liposomal vitamin C which can be taken orally and made at home. If you are interested in getting the benefits of IV vitamin C in megadoses from the comfort of your home, don’t miss this relevant information!

Liposomal Vitamin C


A liposome is like a bag that carries a substance into your body and its cells. It is incredibly effective at this task since it is made out of fat. As it happens, it is the same type of fat that make up cell membranes, making the job of crossing this barrier much easier. Plus, liposomes are super tiny and in that way, they can go through every teensy crack of our cell barriers.

In order to achieve an effective megadose vitamin C dose – for instance, to kill cancer cells – you need to achieve a vitamin C blood level of around 250-350 mg/dl. An average person will typically have around 1 mg/dl on a fairly decent diet. After a 25 to 50 grams IV vitamin C therapy delivered in about a 90-minute period, the blood level is in the 200 to 300 mg/dl range.

Reports say that 6 g of oral liposomally-carried vitamin C is equal in delivering vitamin C inside cells, where it does its work, to 50 grams of intravenous vitamin C.

To make Liposomal Vitamin C, you need an ultrasonic jewelry cleaner like the one in the image. Just type on amazon.com or other store of your convenience and see which size is the most practical one for you.

Then you’ll need sunflower lecithin or non-GMO hexane free soy lecithin, and the vitamin C, preferably as sodium ascorbate.

3 level tablespoons of lecithin.
1 level tablespoon of sodium ascorbate.
Dissolve the lecithin in 1 cup (240cc) of warm or cold water, preferably distilled. Let it soak for a couple of hours or so. It doesn’t have to clump, so using warm water is preferable (not hot!).

Dissolve the sodium ascorbate in 1/2 cup warm water, preferably distilled.

Pour both solutions together into the ultrasonic cleaner and mix for around 20 to 25 minutes.

A loading dose, for several months, of liposomal vitamin C is likely 2,000 mg three times a day, maintenance , 1,000 mg twice daily, increasing doses and amounts when needed.

This recipe provides 12 grams (12000 mg) of Vitamin C Ascorbate at about 70% – 90% liposomal encapsulation efficiency. It will keep at room temperature for about 3 to 4 days and refrigerated, it will keep much longer.

Recall that 6 grams of this stuff is the equivalent of 50 grams IV vitamin C. So you can take half the solution throughout the day for a day or two in case of illness. Wean off gradually throughout the days though, so no artificial drastic lack is perceived by the body.

I’ve used 3 tablespoons of sodium ascorbate with good absorption results as well. Three tablespoons instead of one tablespoon as indicated in the above recipe will yield around 16 grams of vitamin C per cup. The absorption of the liposomal variety is about 5 times the absorption of vitamin C straight, so that is approximately 80 effective grams (IV therapy).  That is a very high dose indeed! You will have to take that one cup throughout the day though, I doubt you’ll tolerate drinking in one seat without having diarrhea.

A note of caution


Those with iron overload (ask your physician to test for ferritin, transferrin, TIBC and iron) should keep in mind that vitamin C increases the absorption of iron into the body, especially in the heart where it can cause heart failure, palpitations and others. Ferritin levels should be ideally less than 80 and transferrin saturation should be less than 40%. If you are above those levels, you might want to donate some blood or refer to the Iron Disorders Institute. A great book on the subject is The Elephant Iron by Roberta Crawford.

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  1. Rodriguez  November 1, 2014

    I use the recipe from qulityliposomalc.com and here are some tips from experience. 1) It works really well, I don’t even use an ultrasonic cleaner 2) If you are making 1 cup or 240ml it takes about 3 days to be good and ready, if you are making 2 cups or more it could take up to 5. Reason is because of the amount of alcohol, I believe it evaporates, degrades, or contributes to the process, I dunno, whatever it does it dissapears the more you blend and the more days it sits. I took a shot straight after I made my first batch and could feel the alcohol in my system, after a few days the alcohol is non existent. Also I think the higher the percentage of alcohol, the quicker the process. With 40%, because of the process it takes to make the vodka, it longer to evaporate because there is other ingredients.

    • Marcella Smith  November 2, 2014

      Hi Rodriguez, how did you know it was ready on day 3? Did you check it under a microscope? I would love to see the spheres of lipids to know for sure that it actually occurred. There is a good picture on his website, but I would like to see if I am doing it correctly.
      Also, I didn’t think it took 3 days, why so long?

      • Gaston  March 24, 2015

        “All I can say is that the simple ultrasonic treatment of lecithin and vitamin C does not make liposomes. I have reviewed the sophisticated testing of two different such preparations. Both of them: zero liposomes.

        However, the ultrasonic treatment does result in a legitimate emulsion, which is absorbed much better than just regular vitamin C. However, that is just absorption into the blood, not enhanced uptake inside the cells, as with liposomes.”


    • John S  May 5, 2015

      Unfortunately, the author – Chris – of the Qualityliposomalc site has not allowed anyway to contact him to warn him of the dangers of megadosing of Ascorbic Acid. NEVER EVER EVER use Ascorbic Acid to make Lipo-C. The body is forced to immediately buffer it to avoid dangerous shifts in blood serum pH. This forces the body to leach minerals from organs and other tissues. There are a host of dangerous side-effects that are possible depending on the individual’s condition and health. This can be LETHAL. ONLY use SODIUM ASCORBATE> I will be publishing a free website and eBook and PDF to describe all of this soon because there is so much misinformation online. BTW, Livon labs uses ascorbate in their patent, NOT ascorbic acid. Also, the method Chris uses to create the liposomes wastes over 30% of the effectiveness of the C by the time it is encapsulated due to his process technique. All will be explained.

      • Gabriela Segura, MD  May 6, 2015

        One thing is to use sodium ascorbate to do liposomes. Another thing is use titrating doses of ascorbic acid. The clinical experience, both available and personal is staggering. Ascorbic acid is by far one of the best nutrients available to deal with very debilitating diseases. For more info, see http://orthomolecular.org/ and http://www.sott.net/article/284126-Vitamin-C-A-cure-for-Ebola

      • Lucy  May 29, 2015

        Please John, tell me where I can read your free website or ebook. I have been taking home make Lipo-C with Ascobic Acid about 8g a day to fight cold. Could you tell me what the side effects are? Thank you.

      • Carole Carrick  June 16, 2015

        Hi Rachel,
        have you written your book yet? Or have you got your website off the ground re making Liposmal C?
        Up until a month ago I’ve been making various non-alcohol versions and pouring it directly into the ultra sonic machine. Some with bi-carb, some not.
        I only just realized that getting a 22% Phosphatidyl choline content in the lecithin (or greater) was essential or there would be insufficient fat to encapsulate adequately.
        Recently I began making Chris’ version with Alcohol, but am now confused as to whether I can use my ultrasonic machine with the mixture poured directly in the machine or must it be in a beaker in water in the machine? Some emntion I special type of glass you need to buy in a laboratory supply place. No plastic. (The blender I use is non-breakable, non-glass to add to the confusion.) .I’ve hence stopped using the ultrasonic altogether.
        I also don’t understand why it needs to rest 2 hours in fridge between blends, and to take 24-48 hour before using ultrasonic. My blender does not heat the mixture at all after 2 minutes of belending, so keeping below 32 degrees C is never a problem.
        Some websites like one quoted on this page says it’s not beed scientifically proven that you can make liposomal C at home anyway. So go back to LiveOn!
        The conflicting information, misinformation and lack of scientific validation and testing makes it very confusing for the average home user. Thank you. Carole

  2. Rachel  November 5, 2014

    Thanks for your comment I have been looking for someone or info on the role that Alchohol plays and if it won’t affect the liver, I tried the method on the website qualityliposomalC and it calls for too much Alchohol, I can’t afford livons satchets anymore and I really need to be sure I’m creating quality lipo, just worried about using Alchohol

    • Richard  November 5, 2014

      Hi Rachel, as the research mentioned on that web site says, alcohol helps the formation of liposomes. They form naturally anyway, but more readily and in better, smaller sizes with the addition of the right chemicals. Alcohol just happens to be the least nasty of the chemicals the researchers have found effective.

      Livon uses 12% alcohol too — says so on the package. I think that’s where Chris Davies got the number for his recipe on the web site. I think Livon suggested you could open a package and let it sit for a bit before consuming to let some of the alcohol evaporate.

      Considering how small a dose of lipo-C is, it really doesn’t seem like much alcohol anyway.

      There are a few tricks for consuming lipo-C if your main objection is the taste. Try placing one or two ounces of water in an empty cup before adding the lipo-C into the middle. Then swirl the liquid around the cup and swallow it in one motion. The water will keep most of the lipo from touching your taste buds. (Works slightly better with Livon lipo, since they add chemicals to keep theirs clumped together.)

      If that’s not good enough then get some Mio or Kool-Aid liquid and add a tiny squirt to your mix. Orange-flavored Kool-Aid liquid makes lipo taste a bit like orange sherbert. Tastes pretty good. (Probably best not to mix too briskly, to keep from disturbing the liposomes.)

      • Rachel  November 6, 2014

        Ah thanks Richard that really helped I was making my own vitC using 1 tablespoon of Vit C and 3 tbls of Lecithin granules in my small UC, I got very dissapointed when I caught a nasty flu and tonsils that got me down the whole week, after taking my homemade mixture religious for the past 3 months :(
        When I saw Chris’s website I knew I had to make them the right way, oh and the flu stated a week after my GSG livon satches got finished, now our supplier in South Africa said she doest have stock, Livon makes the best but its difficult for me when I run out, hopefully Chris’s recipe will be the one…the taste I don’t mind was just worried about 115g of Ethanol in my system and if it wont hurt my liver and end up failing breathelizer tests :)

  3. jan Brown  November 6, 2014

    Hi, I’ve just made my first batch and find the taste of this really bad. Can it be mixed with orange juice? Also I’m trying to heal my adrenals and need lots of vitamin c but I’ve noticed that my adrenals seem to be struggling over the past few days (since I’ve been taking this ) could my body be detoxing?

    • Gregg  November 28, 2014

      Mix in some fresh lemon juice and organic liquid stevia to taste. That should help.

    • gypsyboots  December 29, 2014

      Dr. Lam on his vit c safety site DOES mention that those with adrenal exhaustion can experience fatigue and increased anxiety,malaise,joint pain and heart palpitations due to a herxheimer or healing crisis…take a coffee enema..always helps me to clear out toxins faster. Gypsy

  4. Sula Maye  November 17, 2014

    where do you buy the ingredients for this and what is it that the jewellry machine does to process the ingredients. I am confused. Is there anyway of making it without the machine?

    • Gabriela Segura, MD  November 17, 2014

      It aims to create the liposomes described in the article. You can get the ingredients at a cheap price in websites such as iherb.com, evitamins.com. Perhaps others will have better sources.

      • steve  January 18, 2015

        A couple of other places you can get ingredients are Swansons and Vitacost and of course Amazon.

  5. sophie  November 22, 2014

    about Chris`s method; I wonder if we could use vaccuum chamber to remove air bubbles from the mixture? It would lower the alcohol and air for sure, but I do not know if it wouldn`t breake up the liposomes . Any comments for this topic?

    • Marcella Smith  November 23, 2014

      That sounds like a great idea! The way to test it would be to do it, then look under a microscope to observe the liposomes. I wonder if Chris can or will do that?? I had how long it takes to reduce the bubbles and warming a Vit C solution does degrade the C, it only takes a few minutes to suck out bubbles with a vacuum container!
      I will be watching!

      • Marcella Smith  November 23, 2014

        I mean ‘I hate how long it takes to reduce the bubbles’, sorry have a big bandaid on my thumb, its messing me up! haha

  6. Kerim  November 26, 2014

    Dear Gabriela, Chris, and others:

    Can you please advise about the reaction I had to taking the Liposomal C…and what alternatives are available? I really want to try the benefits of Liposomal C, but can’t do that unless can get around the reaction.

    Approximately 1 week after starting to take it, I developed a moderately severe (very uncomfortable and constant) subcutaneous itching (especially face, neck, torso and arms) and a rash–like hives–in some of these locations. It was so uncomfortable that I stopped taking the Liposomal C completely and the itching took a week to die down.

    I am assuming it was an allergic reaction….and, from internet research, it seems more likely to be a reaction to Soy Lecithin (common) rather than the Vitamin C itself (less common). And I assume it can’t be to Vodka, since I can drink Vodka normally without any problem.

    FYI – In case this matters: I used Chris’ recipe and directions from qualityliposomalc.com, using Soy Lecithin, Ascorbic Acid, Vodka and water. I don’t have a fine scale for measuring. Since Chris uses weights of ingredients, I converted them all to volume (cups) using the conversion of water at 100g = .435cups in order to make a total volume of 1.5cups:

    Ascorbic Acid 1/3 cup (to approximate 119.53grams)
    Soy Lecithin 1/3 cup (to approximate 92.54grams)
    Vodka 2/3 cup (to approximate 158.59 grams)
    Water. 1/2 cup (to approximate 119.53grams)

    Perhaps doing this rough conversion might also be contributing to the problem? You’ll see that the total volume is actually 1.8 cups

    Thank you for any advice you can offer.

    • Gabriela Segura, MD  November 27, 2014

      Hello Kerim,

      From my side, I decided to take oral ascorbic acid, leaving liposomal as a coadjuvant boost for emergencies. I’m not sure I tolerate soy lecithin myself. Since I switched, I noticed a marked improvement: more energy, slept better, better hair quality, etc. I was tolerating +20 grams of ascorbic acid at the beginning, a record amount considering I’m in the ketogenic diet where typically I only tolerated 2-4 grams. Then after awhile I reached my limit and started tolerating only 4 grams maximum again. Any now and then I tolerate more, for example, when I’m doing shift hours which are very stressful. For more information, read the following article:


      Types of vitamin C

      Straightforward, low cost ascorbic acid is the preferred form of supplement. Vendors may try to sell you “better absorbed” forms with minerals or salts such as sodium, potassium or calcium ascorbate, and so on. These are irrelevant, if not counterproductive, for high intakes. It is worth noting the following:

      Timing is more important than form. Two large doses of ascorbic acid taken a little time apart are better absorbed than a single dose of mineral ascorbate.
      Mineral ascorbates are salts and do not carry the same number of antioxidant electrons. Ascorbic acid has two electrons to donate while a salt typically has only one. With high doses, the “improved” forms are thus only about half as effective. This is consistent with reports that mineral forms are correspondingly ineffective in combating illness.
      Ascorbic acid is a weak acid, much weaker than the hydrochloric acid in the stomach. Mineral ascorbates may be better tolerated, as they make the stomach more alkaline than ascorbic acid. However, an alkaline stomach is not a good idea – there are reasons the body secretes hydrochloric acid into the stomach, including preventing infection. Furthermore, if you are coming down with a haemorrhagic viral infection, mild discomfort will not be something of great concern.
      For high intakes, capsules of ascorbic acid are preferable to tablets. This is because tablets are packed with fillers and it is not wise to take massive doses of these chemicals. Check the ingredients – you want to take ascorbic acid and very little else. Bioflavonoids are alright, and the capsules may be made with gelatine or a vegetarian equivalent.
      The cheapest way to take ascorbic acid is as powder, dissolved in water. If you do this, use a straw to avoid it getting on the tooth enamel, as it is slightly acidic. You will need a set of accurate electronic scales to monitor the dose. If you do not weigh it carefully, it will be difficult to keep close to bowel tolerance.

      Other people told me that since they switched to ascorbic acid, they also noticed a marked improvement. Since then, I recommend oral ascorbic acid, adding the liposomal version if needed and/or if you want to increase your C levels in blood as stated in the article above.

      My 2 cents!

      • Richard  November 27, 2014

        I agree, somewhat, Gabriela.

        Liposomal C is wonderful, powerful stuff. But it’s probably overkill for everyday use.

        But Ascorbic Acid is a poor alternative. Ascorbic Acid is for plants. Humans need Sodium Ascorbate.

        Ascorbic Acid is easier to find and cheaper. Though not by much. But it rots your teeth, burns your skin and simply doesn’t match your system’s needs. Linus Pauling used lots of Ascorbic Acid, because it was plentiful and cheap. But he converted it to Sodium Ascorbate by adding baking soda.

        Sodium Ascorbate is pH neutral. You can brush your teeth with it. (It does wonders for strengthening your teeth and gums.) You can pour it directly on wounds and skin. It speeds healing like crazy. You can mix it with water and drink it up without upsetting your stomach. It’s pH balanced. Ascorbic Acid is NOT.

        Taking lots of Ascorbic Acid will eventually give you other problems, like gout. You body does a good job of balancing pH. But not when you overdo your acid intake constantly.

        And Sodium Ascorbate is NOT table salt (NaCl.) It does not exascerbate hypertension as salt supposedly does.

        Soy is a common allergen. According to recent research many people with no apparent soy allergy often develop one after extended contact with soy. Towns containing soy processing plants tend to have elevated numbers of citizens with acute soy allergies, apparently from dust in the air. Soy allergies often become worse over time, and can become life-threatening.

        Latest research suggests that folks with peanut allergies should protect themselves from soy, as the two are apparently related.

        Lecithin is good stuff! It’s good for your brain. A gram or so a day can help you think and remember better. Sunflower Lecithin is probably the safer choice. You can make Lipo-C from Sunflower Lecithin too.

        I take between 10 and 20 grams of Sodium Ascorbate mixed in water. Taken in doses spread throughout the day. I brush my teeth with it occasionally. It toughens my skin and gums. I no longer cut myself shaving, even when I’m careless and think I have. Young skin is back. I apply it directly to cuts and skin abrasions, sometimes mixed with Aloe Vera juice/jell. Great stuff! It’s not a panacea, but sometimes it comes close.

        Ascorbic Acid is cheap and available everywhere. But it’s not appropriate for humans (except for occasional use.) Sodium Ascorbate powder is available at health food stores and online. It’s a much better choice.

        Stay healthy!


      • Kerim  December 1, 2014

        Dear Gabriela and Richard. Thank you both for considerable replies.

        Two questions:
        1) I am trying to address golden staff and streptococcus bacteria, chronic sinus infection and other things. While none of these are extreme or crippling at the moment, they are uncomfortable, place a drag on energy, immune system, gut and general well being…and probably are having other effects medium and longer term.

        Is oral C likely to make enough impact on these things, or should I try sticking with Liposomal using Sunflower Lecithin? I am certainly leaning towards giving it a go.

        2) I am confused by the strong and conflicting views of ascorbic acid vs sodium ascorbate.
        Gabriela, I’m wondering if it might be better to use SA in order to avoid the potential problems (tooth decay and acid in blood–not stomach), and accept the lower efficacy. Liposomal gives a much higher efficacy than its anyway, which might still provide significant benefits, even if not same as ascorbic avid.
        What do you think?

        Thanks again…

      • Gabriela Segura, MD  December 1, 2014

        Hello Kerim,

        If SA works for you, I would stick to it. Some people find ascorbic acid strong for their stomachs and enamels. I take the “bite” off with stevia or xylitol. I find it is better tolerated that way. As for health problems in general, I would encourage you to check the ketogenic diet, i.e. “Ketoadapted” by Maria Emmerich. Ketone bodies have therapeutic and rejuvenating effects on the body, and the diet cuts down on carbs/sugar which always makes everything health-wise worse. Another trick for chronic sinus infections: Sniffle pure nystatin powder by both nostrils. It helps with fungal infections as chronic sinus problems almost invariably involves fungi such as candida and others. You can order nystatin in powder form from fludan.com:


        You don’t have to take it orally, just sniffle it through your nostrils two or three times per day. It will help it go away.

        As for lead, do check out EDTA supplementation for lead toxicity. For instance, _http://www.drsinatra.com/get-the-lead-out-with-oral-chelation/


    • Margaret  January 25, 2015

      Try using sunflower lecithin.

    • John S  May 5, 2015

      As I mentioned above this morning, the dangers of Lipo-C made with Asccorbic Acid are plethora. You are experiencing one of many that can happen. It is simply because it is the ACID form of C. To fight infection, our bodies need ALKALINE, not ACID. Our bodies MUST keep our blood serum at pH of 7.35 – 7.454. IF it gets out of that pH range, it can be lethal to us. When Ascorbic Acid is released from the liposomes either in cells or into the blood by the liver as they are broken down, the Ascorbic ACID is immediately lowering the pH way out of healthy range. The body is forced to immediately begin leaching minerals from organs and other vital tissues including skin where there is a wealth of capillary action to be able to buffer – neutralize – the pH imbalance caused by the Ascorbic ACID. Mega-dosing of unbuffered, or non-neutralized Ascorbic Acid may also cause various dangerous interactions and reactions like hypoglycemia, hypocalcemia, hyperkalemia, acidosis, kidney damage, etc. This is why megadosing of Vitamin C can be lethal if it is not done ONLY with the fully buffered form called Sodium Ascorbate. NEVER, NEVER, NEVER with Ascorbic Acid. I will be publishing a complete website with PROPER information, eBook and PDF to be available to all soon complete with links to research from clinical, academic and anecdotal. There is so much misinformation on the web, people. Be Careful and do your OWN research. Don’t rely on someone else.

  7. Kerim  December 1, 2014

    PS- also trying to eliminate very high levels of lead, as shown in hair sample testing. I’m told that lead is “death by a thousand cuts”, meaning there are no single major consequences, but rather many many gradual ways it degrades the body and wellbeing.

  8. Kerim  December 1, 2014

    (Autocorrection error)
    First post above should read “Liposomal C gives a much higher efficacy than ORAL anyway…”

  9. Jake  December 2, 2014

    You can also buffer any ascorbic acid with a product called Tri-Salts to balance the ph. This is also important because Vitamin C will drain minerals from the body. So the Tri-salts have a 2 way effect, balancing the ph of the acidic C and replenishing minerals at the same time.

  10. Marcella Smith  December 3, 2014

    First, I can’t seem to find the link to Chris’s website as I need to make a fresh batch of Lip C.

    Also, I too am confused with Richard’s comment on Absorbic Acid vs Sodium Ascorbate.
    1 – Absorbic Acid is found naturally in many foods such as Oranges, peppers, tomatoes, berries, to name a few.
    2 – Sodium Ascorbate is a man-made product, only made in the lab,

    So, how can AA be only for ‘plants’ and SA be only for humans?
    That didn’t make sense to me.
    Vitamin C is a huge tool of our immune system, which is designed to work hand in hand with Vitamin C, how could our body be designed to work with a man-made product?
    If we don’t eat lots of fruits and vegetables than we have to supplement to stay healthy,
    how does supplementing with SA help make us healthy?

    Just wondering if you have more information to support the AA vs SA assertion. I am beginning a new batch of Lip C as I am surrounded by Flu/Strep/Viruses in the clinic and would like to go for the best type of C


    • Richard  December 4, 2014

      Pardon my quick response. I’m short of time at the moment. More later …

      Sodium Ascorbate (NaC6H7O6) and Ascorbic Acid (C6H8O6) are both common forms of Vitamin C.

      In my opinion, SA is much more convenient. Add water and you can even inject it intravenously. AA will damage your veins.

      SA is the accepted form for injection. Ingested, it won’t upset your stomach. The bowel tolerance reaction is much gentler. Gas versus diarrhea. It tends to reverse gout instead of inflaming it as AA can.

      Commercial Lypo-C producers use SA.

      Untamed AA will etch your teeth and inflame most any body part it comes in contact with. SA is very good for your teeth and gums and can be applied directly to the skin or to cuts and burns. It hastens healing better than most anything. Makes a great sinus wash, too.

      The acidity of AA causes problems. SA fixes those problems. The stomach tends to adjust for AA’s imbalance. But large doses, taken every day, can take their toll. I feel strongly that taking AA daily for many years contributed to my gout. After switching to SA the gout has gone away.


    • Sophie  December 4, 2014

      http://qualityliposomalc.com/ – chris`s website
      I made my first batch useing Chris’s recipe with AA and sunflower lecithin. There was not so many air bubbles, and the mixture was thick, not liquid. It is so strong & sour, but I drink it in water. It hepls. I’m really thankfull to Chris for His work, but there is no place to say it on his website.

      • Marcella Smith  December 4, 2014

        Thank you Sophie!

        I was frustrated that I had not put Chris’s recipe website on my FAVORITES list, now it is.

        I agree it is hard to keep the air bubbles under control, and as soon as you start mixing the solution the Vit C begins to degrade thru oxidation. So the faster you can get the air bubbles out, the better, so that the sonic vibrations can create more lipo-sheres.

        Also in the mix of issues making Lipo C is heat, heat destroys Vitamin C, so watching the heat, putting the container back and forth in the frig to get the best quality is labor and time intensive.

        I am only using the Lipo C in small batches or runs so not that big of an issue. Otherwise, I take about 6-8 grams of Ascorbic Acid spread thru the day.
        It has keep me free of most issues except a day or two ago I started to get a little bit under the weather,
        so I added more C and ‘Viva’ brand Glutathione (Amazon), and now I am back to my regular self, but I think a few days of homemade Lipo C should really help.
        I found a refrigerated capsule form of Lipo Glutathione, seems a better quality, I now take daily also and will thru the cold/flu season, although a bit expensive, got it from: http://www.purecapspro.com/healthyheartandbody/pe/products/product_details.asp?ProductsID=1783 .
        I work in a clinic where 90% of my patients right now are strep/flu/sinusitis/bronchitis/and the common cold :). Done well so far (knock on Vitamin C wood, lol)


  11. don  December 4, 2014


    I am planning to do a Vit C flush with sodium ascorbate now. But my P-feritin level is 294. The max i see on my paper, is 300. Should i worry about it? My doc said it all looked fine.


  12. Dr. Noria  December 19, 2014

    I am a nutritionist and food scientist, with a Masters and Doctorate degrees in both fields.
    I am saying this just to indicate that I do not talk about this subject from guessing, or believing everything that is posted on the internet.
    I do acknowledge that the liposomal theory, that certain substances can be absorbed much better, but I have not tried it myself yet.
    The thing that I do not agree with, is what some people say, that if you use Ascorbic Acid, in its liposomal state, it will damage your teeth, and affect your stomach.
    Let me explain in simple terms how liposomes work in the body, when a true liposomal system is created, and ket’s assume it is a vitamin C liposome, if according to the theory of the liposomal physical structure, ( by the way, the liposomal physycal structure has been shown and proven by pictures through microscopes), every tiny molecule of Vitamin C, or a large portion of it, is coated with the lecithin, which the carrier of Vitamin C, and it is the avenue that allows the Vitamin C to cross the cell membrane, which means that the cells in the mouth, teeth, gums, are touched by Vitamin C, the same happens through the cell linings of the esophagus or the stomach, until the tiny liposomes cross the cell membfanes and enetr the cells.
    So, the thinking that Ascorbates are are better, or safer, is not correct, actually, Ascorbates are absorbed much slower, and a lower amount is absorbed in the cells, for this reason, when you make the Vitamin C liposomes, you need to add three times as much of the Ascorbate, because the Ascorbate molecule is made of Ascorbic acid and a mineral, it could be Sodium or Calcium, usually, and too much of either ones of those minerals entering your cells will cause a havoc in your intracellular and extracellular ionic system.
    Which takes us to why Vitamin C heals, it is about electrons in it in the body, which neytralize the free radicals.
    I hope that I clarified, that true liposomal Ascorbic acid is better than liposomal Ascorbates, now, intravenous Vitamin C is another story, in this case, the veins over time, may be affected, but if one uses this method fir few times a week, then the veins can actually become more flexible, and resilient, i.e., stronger and healthier.

  13. Dr. Noria  December 19, 2014

    I apologize for the typos, I am not a good typist, but I hope I got the info to all that would like to benefit from the lipo Vit. c
    I meant to say in my message, that the liposomal Viamin C using Ascorbic Acid, DOES NOT damage or hurt the linings of your internal organs because of the acidity, because the Ascorbic Acid molecules are coated with the lecithin, which has, actually, several functions, the ones I know about are, coating the vit. C, which enables it to be absorbed into every cell, also, it protects the linings of the mouth , gums, and teeth, from the acidic effects, and lecithin is beneficial for several parts of the body, an obvious one is the brain.

    • Richard  December 20, 2014

      At some point, liposomal encapsulated Vitamin C is delivered to it’s target. Then it is no longer protected by encapsulation. Injected Vitamin C is only done with Sodium Ascorbate. Never with Ascorbic Acid. The latter would damage artery walls and other internal structures. Acid is not good for the circulatory system, or for most other internal structures for that matter.

      Homemade Lipo-C probably WILL etch your teeth. No one has yet achieved 100% encapsulation. So some C exists in the fluid outside of the liposomes. For homemade Lipo-C that could be as much as 50% of the C involved.

      All commercial versions of Lipo-C that I’m aware of use Sodium Ascorbate. It costs a little more, but the health reasons for choosing it are well documented and overwhelming.

      Lipo-C helps it’s cargo, Vitamin C, bypass the body’s first line of defense unimpeded. That’s a very useful thing. And a potentially dangerous one that should be taken seriously. You can eat dirt and survive. Your digestive system will protect you. Encapsulate that dirt in liposomes and you may be in big trouble. Be careful when you make your own liposomes. Make sure everything is very clean, every step of the way. And choose what you put inside very carefully. Science says Ascorbic Acid is not a good choice. Do some research. Or take your chances … I prefer to do research. So I’ve done a whole lot of it. Always more to do.

      Some research does suggest that Ascorbic Acid is assimilated more quickly than Sodium Ascorbate. Though not by much. Considering all the other issues, I’m not impressed by a little extra speed. There are indications that Sodium Ascorbate may be a little more bioavailable, depending on many factors.

      In conclusion, using Ascorbic Acid for liposomal C is not a good idea. pH levels of our internal systems are generally maintained within close tolerances and do not respond well to abrupt changes. We take C to improve health. Poorly pH-balanced C in critical places threatens to do the opposite.

      Please be careful.

      • Brian  December 21, 2014

        Are you the Richard Dalt that has helped heal himself from Myelofibrosis using Liposomal Ascorbic acid (vitamin C) and selenium = sodium selenite?

      • Richard  December 22, 2014


        No, that’s not me.


      • Charles marriage  January 1, 2015

        I can!t see that ascorbic acid could be better than salts of ascorbic acid, because ascorbic acid in sloution is always ionised, and the body’s reaction excess acidity (toomany H+ ions) wouls be t buffer them with something else. For example I Have read that. Increased lactic acid from rxercise is buffered by calcium from your bone. If theantioxidant properties of vit C depended on its acidity we could all drink lemon juice, eat really nice acid yogurt etc.

        Sorry about all the typos – I blame my ipad.

  14. Graceread  December 24, 2014

    Richard, Can you recommend which brand of Sodium Ascorbate to take? When looking at reviews there are mixed feelings. I am wondering about corn/GMO used in these powders. Can you advise?
    Thank you.

    • Charles marriage  December 28, 2014

      I see no reason to worry about gmo’S etc. . Sodium ascorbate is a simple chemical compound made from glucose. Buy from non-American sources if you are really not sure

      • Richard  December 29, 2014

        Good response, Charles. I use the cheapest one I can find. Sodium Ascorbate is a very simple compound.

        I use Nutribiotic brand from an outfit on ebay. 2.2 lbs for $32 with free shipping.

        Sorry for the delayed response. I was away for a week over xmas.


  15. Tammy  December 27, 2014

    Hi Richard,
    I have all the ingredients to make lyposomal V.C. I also have 6 ounces of powdered vitamin C from Acerola berry. Please walk me through your suggestions on correct mixing and dosing. Thanks Richard. I appreciate your knowledge sharing to someone like me. Thanks again!


    • Richard  December 30, 2014

      Hi Tammy,

      I like Chris Davies recipe using Sodium Ascorbate instead of Ascorbic Acid. I substitute Sunflower lecithin because I seem to be allergic to soy. It’s probably okay to use less alcohol too, since you do get some liposomes even without it. I use half what Chris’s recipe calls for. I have a good ultrasonic cleaner so I use that for an hour instead of all the blendering.

      But, I’m not currently using Lipo-C. I’ve been using large doses of Sodium Ascorbate by itself for almost a year. I was anxious to learn more about the capabilities of Vitamin C without the additional effects of all the lecithin that Lipo-C brings with it. C is good stuff. So is lecithin. I’m not sure about large doses of lecithin though.

      Lipo-C seems like a great tool when you’re really sick. But overkill for every-day use. Ten or twenty grams of Sodium Ascorbate daily goes a long way to keeping me in great health. If I get the flu I might double that, and it will knock down the symptoms right away. Way safer and better than getting a flu shot in my opinion.

      I’ve been finding some other supplements recently that seem to help C do it’s job better and potentially with smaller doses. Still looking into those.


      • Steve  December 30, 2014

        Is natural wholefood C much better to use that a synthetic C. Surely something like Acerola powder, or Camu Camu, would be better accepted by the body?

      • Richard  December 31, 2014

        There are a lot of dressed up supplements being sold at premium prices. Some may be helpful. My experience says they’re usually not.

        All the honest research seems to say that there’s no difference between the various Vitamin C offerings in terms of effectiveness.

      • Charles marriage  January 1, 2015

        I think that taking vit c when blood sugar levels are low improves absorption. If i take it near mealtimes then my urine is bright yellow indicating vit c in the urine. I suppose that i could test with test strips, but i havent found cheap UK sources for them. Meanwhile I try to take mid mrning and at night

  16. Tammy  December 27, 2014

    Ps. I’m not preparing anything until I hear from you! Please hurry! I’m a baby nurse that works nights, and go back to work in 2 days.

    Thanks again! Your awesome!

  17. Debbie  January 12, 2015

    Hello Dr. Segura,

    I’m going to try your original recipe up top for liposomal C with sunflower lecithin….the rest of the thread is interesting, but too confusing :)

    I just have one question – what does the jewelry cleaner do?

    Thank you,

    • Gabriela Segura, MD  January 12, 2015

      Hello Debbie, It is supposed to make the liposomes. Hope it will benefit you! Best!

  18. Joy Warren  January 14, 2015

    I am trying to find organic non-gm, sunflower lecithin since I am horribly aware that even if a product is non-GM, farmers have the nasty habit of using glyphosate herbicide (Roundup) on soil surrounding their crops. As a commentator has said further up this string, what you have in your liposomes is carried into your cells and I definitely do not want glyphosate anywhere near my cells. I’ve looked on the iHerb.com site and the evitamins.com site and they both sell NOWFOODS lecithin which seems pure enough, until you read between the lines. NOWFOODS avoids the use of the word “Organic”.

    Is it not a case of doing more harm than good if the lecithin is not as pure as driven snow?

  19. Roger  February 9, 2015

    I have Asymptomatic Myeloma and have been using your recipe for making liposomal Vit C for some time. I have been taking 6000mg (half the mix) per day for 6 months now. I have been relatively stable, but now things have gone down- hill a bit. My GP is appalled that I have been taking this quantity of vit C and says that there evidence to say that long term use of mega dose Vit C can cause kidney damage. Especially with a disease that damages the kidneys itself. The presence of protein in my urine, he has said, may be an indication of early renal damage.
    I have discussed the way our NHS railroads you onto the “treatment without adequate time for patients” treadmill and the pressure from the big Pharma’s, but he says that he cannot find ANY clinical evidence or published research for doses greater than 1500-2000mg per day. He also pointed out there are a wealth of warnings about the risk of potential damage. He is genuinely concerned and we have had a second opinion from another GP with the same result. He has no problem with alternative treatments and take 1000mg Vit C per day himself and appears unbiased.
    Whilst this is my body and I can chose whatever treatment I want, I would be a fool to ignore good advice. Can you point me toward any published research that I can use to argue the case for Mega Dose Vitamin C?

  20. Candice  February 14, 2015

    Would it be possible to use a whole raw milk instead of the lecithin to encapsulate the vitamin C? I’ve got the natural vitamin c instead of the ascorbic acid, but I’d like to take it a step further and make all the ingredients as unprocessed as possible.
    Thanks for any info or thoughts on this.

    • Gabriela Segura, MD  February 14, 2015

      That is one way to go, although there might be other reasons why you want to use lecithin:



    • Richard  February 14, 2015

      Liposomes are very special. You can’t find them just anywhere. They occur naturally in some constituents of lecithin. And almost nowhere else. Not in milk.

      And milk is one of the most unhealthy foods available. A really, really bad choice. Do some research, please. Don’t read the stuff that comes from the milk industry.

      Stop drinking milk and you’ll live longer and healthier.

  21. Juie Rider  February 22, 2015

    How do you answer the critics who say we should not be taking ascorbic acid but whole food vitamin C?

  22. Michael Silverman  March 21, 2015

    Hello Dr.
    I have a sensitivity to alcohol and very little disorients me, makes me feel queasy, dizzy and even knocks me unconscious. Will making the liposomal c with vodka, actually leave vodka in the final mixture that will adversely affect me, or does the heating evaporate the alcohol? If the alcohol is still present and potentially bad for me, can I make the alcohol formula without the alcohol but with proportionately increased water to effect the same (maybe not quite as potent) result? I’m battling with thyroid cancer.
    Thanks in advance for your help .

  23. Alfonso  April 12, 2015

    Hi, Gabriela,

    Thank you for this valuable information.
    However there is something I don’t understand. I don’t know if is an error while writing or a mistake of mine
    You have written: “Recall that 6 grams of this stuff is the equivalent of 50 grams IV vitamin C”
    But after that, in another paragraph you also have written: “I’ve used 3 tablespoons of sodium ascorbate with good absorption results as well. Three tablespoons instead of one tablespoon as indicated in the above recipe will yield around 16 grams of vitamin C per cup. The absorption of the liposomal variety is about 5 times the absorption of vitamin C straight, so that is approximately 80 effective grams (IV therapy)”
    Have you meant 36 instead of 16? and liposomal oral absortion is 5 times more than straight, but more than 8 times than intravenous?
    Maybe I am not understanding correctly the text but is important to me in order to make up correctly the recipe and be sure my wife is taken the appropriate dosage

    Thank you


    • Gabriela Segura, MD  April 12, 2015

      Thank you Alfonso. Apologies if the text was confusing. I meant to say that if three tablespoons are the equivalent of 16 grams and if liposomal is roughly 5 times the absorption of regular C, then 5*16=80. Theoretical absorption of liposomal would be around 80. Hope this helps!

      • Alfonso  April 14, 2015

        Thank you, Gabriela

  24. Lucy  May 29, 2015

    Hi Gabriela, Also I forgot to say that I have been taking Lipo-Vit C about 8g/day(I think it’s correct as I tested foaming with sodium bicarbo and I have not stomach up set at all.) for nearly a week but with ascobic acid and I do not find any flu and cold getting better, still having sore throat, weakness and coughing. Do you know why? I thought Lipo C is very powerful.

    • Gabriela Segura, MD  May 29, 2015

      Hi Lucy,

      As I have reported in the comments, I find plain old ascorbic acid much better than liposomal vitamin C. The latter one can be reserved to increase vitamin C levels effectively. But for your flu, I would try titrating doses of ascorbic acid. Liposomal vitamin C is done with sodium bicarbonate, not ascorbic acid. You can find more info here:


      • Lucy  June 5, 2015

        Hi Gabriela,
        Thank you for your advice. I followed your advice and tried titrating ascorbic acid, but my bowel tolerance is very low. I’m still sick, so I might try Liposome ascobate . I wonder which is better sodium ascorbate straight like Richard or Liposome. Some researches indicate home-made Lip has 0 liposome. But I think at least I can take it without stomach upset. Lucy

      • Gabriela Segura, MD  June 5, 2015

        Hello Lucy,

        If your bowel tolerance is low, you can try with liposome. Even if some speculate that it has 0 liposome, you’ll still be getting the benefits of sodium ascorbate. Best!

      • Joseph thorpe  March 1, 2016

        You mean sodium ascorbate!

      • Gabriela Segura, MD  March 2, 2016

        For liposomal, yes. Good catch!

  25. Bonnie  June 16, 2015

    Thank you so much for the informative article!! I have a quick question…should I take the liposomal vitamin C with or without food? I can’t find that info anywhere.

    • Gabriela Segura, MD  June 16, 2015

      Hello Bonnie!

      I would take it away from foods. Liposomal vitamin C has an overall alkaline effect and you don’t want to wash away stomach acid juices needed for proper food digestion. Best!

      • Bonnie  June 18, 2015

        Thank you Gabriela for your answer! I am learning so much from you!

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