DMSO: The Real Miracle Solution (Addendum – Eye Problems)

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I receive a lot of requests for guidance about the use of DMSO.  I want to make it clear to my readers that I can’t legally give medical advice to anyone who is not my patient.  What I do is research and report on that research.  As for treating the eyes, in particular, I found the following:

Annals of the New York Academy of Sciences

Volume 243, Biological Actions of Dimethyl Sulfoxide pages 485–490, January 1975

DIMETHYL  SULFOXIDE  IN THE TREATMENT OF  RETINAL DISEASE

Robert V. Hill
Department of  Surgery
University of Oregon Medical School
Portland, Oregon 97201

This is a second report on preliminary work with dimethyl sulfoxide (DMSO)  in
the  treatment of  certain  ocular diseases. The  first  report  was made  in  February,
1973,  at  the  Science Writers Seminar  in  Ophthalmology,  in  Los  Angeles.(1)  The
retinal diseases  reported on  there were diabetic retinopathy, macular degeneration,
and retinitis pigmentosa. At that time, DMSO did not appear  to be very beneficial  in
diabetic  retinopathy and macular degeneration,  but  did appear  to  have  some
beneficial effects  in  retinitis pigmentosa.

Since  that  report was  presented,  further preliminary  findings have  given  cause
for  more  optimism  about the  possible  beneficial  effects  of  DMSO  in  macular
degeneration, as well as  in  retinitis pigmentosa. Because of this evidence,  the author
is of  the opinion that more extensive, in-depth  studies should be done on  these two
retinal deterioration gr0ups.(2)  Although the possible effectiveness of DMSO on both
of these groups deserves further study, the author has found it possible  to undertake
an extensive, in-depth  study on only one group at this time,  the retinitis pigmentosa
group.

[…]
PRELIMINARY  INVESTIGATIONS

The  first clue to the possible efficacy of DMSO in  retinal diseases was discovered
inadvertently.  Some  retinitis pigmentosa  patients  under  DMSO  treatment  for
certain musculoskeletal disorders felt that their vision had improved while they were
taking  the drug. Because of  their experience, it was suggested that  the author do a
preliminary investigation on  the effectiveness of  DMSO in  the  treatment of  retinal
diseases.(4)

Such  an  investigation was  begun  in  1972,  after  one patient who  was  suffering
from retinitis pigmentosa had  a  rather  spectacular  recovery  of  vision  after
treatment  with  DMSO.  This  treatment  consisted  of  topical application  of  50%
DMSO  in  aqueous solution  to  the cornea  by  eyecup immersion, for  30  sec, twice
daily. When his  DMSO  treatment  was  started  (February  10, 1972), this  patient
could  see hand motion  only with  his  right eye, and had  a visual acuity  of 20/200
(Snellen)  in his left eye. Five days later (February  15, 1972),  his vision was measured
as 20/70  +  1 in  the  left eye,  and he  could count fingers at 5  ft with  his  right eye.
Three months later, hisvisual acuity was 20/50  in the  left eye.

This patient has continued his treatments daily, except for a 1-week trial interval
without DMSO. He noted that his vision began to get worse during this interval, and
when he  restarted  treatment, his vision  returned  to the level he had just before dis-
continuance. His most  recent  visual  acuity measurement  (January  2,  1974) is still
20/50 in the left eye, and he is able to count fingers at 6  ft with his right eye.

An  additional 50 patients with  retinal deteriorations (macular degenerations  as
well  as retinitis pigmentosa) were  then similarly treated with  DMSO, and  the sub-
jective evidence gathered was also encouraging.(5) This subjective evidence consisted
of  improved  or  stabilized visual  acuity, improved  or  stabilized  visual fields,  and
improved night vision. (The evidence is considered subjective because it requires sub-
jective responses from  the patient.)  Of  the  50  patients treated  with  DMSO,  22
improved  in  visual  acuity;  9  improved  in  visual fields;  and  5  improved  in  dark
adaptation.  Two  patients  have continued  to  regress, and  the  rest  have  had  no
measurable or personally noted changes in vision.

The evidence of  low  toxicity gathered  in  the preliminary investigation was both
subjective and objective. The  objective evidence  of  low  toxicity was  obtained  by
serial fundus photography and  by  slitlamp photomicrography.  No  adverse tissue
reactions  were noted. Subjective reports by  patients on  toxic  side effects included
reports  of  temporary  stinging (usually  20  to  30  sec) and occasional burning and
dryness of the skin of the lid.

Some patients  also reported what might be  called a glare effect. It was accom-
panied by  increased sensitivity to  light, or photophobia,  in  some, and was reported
as simply a blur by  others. This phenomenon occurred within  the first month of  the
initial DMSO  treatment,  after  some early improvement had  been  noted  by  these
patients. The glare or blur lasted for a few days or a few weeks, and after its disap-
pearance,  the  subjects  again experienced subjective improvement  of  vision. This
improvement  was  expressed  as  improved ability  to  get around  at  night, and
improved visual acuity experienced as better perception of contrast.

The findings  of the preliminary investigation raise several questions:

1. Can the subjective findings  of the preliminary investigation be substantiated by
more objective methods of testing?
2.  Are  the  subjective  improvements  noted  in  the  preliminary investigation
anything more  than  the  fluctuations of  vision  usually experienced by  persons with
macular degeneration or retinitis pigmentosa?
3.  If  they are more than this, are  they caused by  the DMSO treatment or by  the
hopefulness of persons who had previously thought there was no help for their afflic-
tion?
4.  If  the  subjective  improvements  are  “real” improvements, caused  by  the
DMSO, how might the DMSO be working  to bring them about?
5. What kind of explanation can be offered  for the glare phenomenon?

[…]

SUMMARY

The continuing investigation of DMSO  in certain retinal diseases is reported. Ob-
jective evidence of  efficacy has not  yet  been  obtained, because  the  FDA phase III
study is only now  starting. Subjective evidence continues to give reason for cautious
optimism, and toxicity appears to be minimal.

ACKNOWLEDGMENT

Inspiration and  assistance in  this study was provided by  Dr. Stanley  Jacob, of
the University of Oregon Medical School, Portland, Oregon.

For more information, please check this article at the Annals of the New York Academy of Sciences.

As to how to apply this treatment – which should not be attempted without consulting your attending physician – I only have reports that it is done by diluting DMSO with physiological solution or sterile saline solution at  25-30% and applied with a dropper twice per day.

Get a small glass bottle with a glass dropper. Make sure you clean it thoroughly and/or boil it for a few minutes.

Get some saline solution from the pharmacy (physiologic solution or sterile saline solution).

Get a 10cc syringe from the pharmacy so you can measure the exact quantities.

With the syringe, put 30cc of saline solution into your small bottle. Then put 9 cc of your pure 99.9% DMSO solution in the small bottle.  Beware that you’ll have to extract and pour the DMSO liquid with the syringe quickly and as you pour the DMSO solution, you’ll feel a resistance in the syringe, so you’ll have to apply more pressure. It might be easier to do it in two steps: first pour 5 cc of DMSO and then pour 4 cc of DMSO.

Make sure your bottle is appropriately sealed and that nothing else enters the solution.

Again, I urge my readers to consult their physician.  Yes, there have been reports of miracle cures, but there have also been reports of this treatment apparently worsening the condition, so a person’s overall state of health and diet may have much to do with the outcome.  Indeed, that is true of any medical treatment and allopathic treatments have a very poor record of curing anything.  But before you take your health into your own hands, please do your own research, consult your doctor, so that you can make a truly intelligent and informed decision.

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Comments

  1. Alan  May 20, 2015

    Anyone tried this? If so how did it go? I and 25 of my family have RP and there doesn’t seem to be any procress in the research that is going on and if and when there is probably wont be able to afford the treatment/cure

    reply
  2. Albert  January 17, 2016

    My Mom was diagnosed with MD at age 75. She did the 50/50 DMSO/DistilledWater eye cup method. Initially, she could only tolerate 2 – not 30 seconds. She says: “It felt like my eyes were being burned out of my head”. The discomfort eventually diminished & she did 30sec, twice/day. She continued for 6 months, when the opthomologist found “No sign of MD”. That was 15yrs ago; Mom is now 90yrs!
    [Saline instead of distilled water is a good idea!]

    reply
    • Gabriela Segura, MD  January 17, 2016

      What a wonderful testimonial, Albert! Very pleased you shared your mom’s story, thank you.

      reply
      • Darlene brehm  February 28, 2017

        Could 10ppm (home made) colloidal silver be used for dilution of DMSO? Thanks. Love Dr Jacob. Have used DMSO orally and typically for 35 years.

      • Gabriela Segura, MD  February 28, 2017

        I know of people who like that mix. Just use DMSO with trusted products.

      • darlene  March 1, 2017

        Just read that 30% dmso is more than adequate for the mix without the burning effect…. Also, have you had any experience of patients using this for glaucoma?

      • Gabriela Segura, MD  March 1, 2017

        Not really, but I read this update from Caroly Dean which sounds promising:

        Glaucoma Calcification
        Carolyn Dean MD ND | Tuesday, February 28, 2017
        http://drcarolyndean.com/2017/02/glaucoma-calcification/

  3. Johan  January 30, 2016

    anything for blepharochalasis?its an mmp originated disease.does it enhance other medicines wich can inhibit these destructive proteinases?

    reply
    • Gabriela Segura, MD  January 31, 2016

      It does, however, don’t combine it with any medicine that you don’t trust. Medicines might have toxic additives in them. I would combine with pure frankincense oil which is good for inflammation. I would also use a very diluted version of DMSO. The eyes are very sensitive.

      reply
  4. John  February 16, 2016

    Hello would dmso also work for albinism?

    reply
    • Gabriela Segura, MD  February 17, 2016

      Not necessarily to reverse it, but at least to help heal the skin after sunburn or radiation. I would use the cream version in order to avoid a burn.

      reply
  5. Shirley  February 19, 2016

    Is there a website of methods and administering DMSO for Ocular problems. I don’t want to make a mistake or use improperly or possibly go blind. Have aute ocular glucoma/ eye pressure build up.

    reply
    • Gabriela Segura, MD  February 19, 2016

      That is the kind of research that suffered when the establishment came down on DMSO. In the 50s, such research would be more common. What I know is reported in this post and in the comments section. You can have your eye pressure measured as you experiment.

      reply
  6. Charles Magner  April 11, 2016

    I have blepharitis in my right eyelid. I have used 99.9 DMSO a couple of times on my eyelid after cleaning lids with everclear. If it didn’t itch so much I would use it more. Am I seeing DMSO and distilled water at 30 cc water top 9 cc of 99.9 DMSO as an eyewash

    reply
  7. Robert McCue  January 27, 2017

    Hi Dr. Segura. Just a quick question about DMSO: Could Omega 3 fatty acid be combined with DMSO for oral consumption and faster absorption?

    reply
    • Gabriela Segura, MD  January 27, 2017

      I would combine DMSO with anything I would trully trust, Robert. BTW, I just published this one:

      Amygdalin – Cure or Poison?
      http://health-matrix.net/2017/01/27/amygdalin-cure-or-poison/

      I’m revising the subject of Omega 3s because they seem to be pretty unstable. That is, you need saturated fat or anti-oxidants to stabilize the omega 3s. DMSO behaves like an anti-oxidant, so I suppose it could be a choice.

      reply
  8. Andreas  April 23, 2017

    Thanks Dr. Segura for your precious help on DMSO.
    I have suffered from Serous Retinopathy events. In one eye it has increased and the macular region is greyed out. The overall vision is okay, but glares, vision distortions, night vision difficulties, keep me always on the edge and scared. It also causes headaches and an unpleasant feeling of the unknown. It’s stress related, I know, and soon my stress level should drop soon.
    i just read and ordered DMSO 99.9% pure and the book. I will let my pharmacist prepare the mix in a dropper bottle. I’m quite “medicine savvy.”
    Can the solution be used as eye drops instead of washes with a cup? I think it would be more practical and less liquid could be used, if localized in the drops. If so, how many drops would you suggest, laying down, and letting them act? How many times a day? Thanks for any help.

    reply
  9. Darla  July 6, 2017

    I was diagnosed with Uveitis four years ago. I have been using DMSO eye drops twice daily for the last six months and have noticed a marked improvement in eyesight and no more light flashes. I began with a 50/50 solution but have since gone on to using nothing but DMSO. It stings but I get through it because I realize its doing such a great thing for my vision that I tough it out. I also use virgin coconut oil around the sensitive areas of skin around my eyes before dropping in the DMSO. I wish there would be more studies using DMSO so as to give people hope.

    reply
    • Darla  July 6, 2017

      That’s exciting news!

      reply
    • Andreas  July 18, 2017

      Hi Darla. Thanks for your input. I have now been using DMSO as reported by Dr. Segura… made a Saline / DMSO solution 10cc to 3cc of 99.9% pure DMSO and had great improvements also. Just wow.
      You said you mixed DMSO to Saline 50/50 and eventually used pure 99.9% DMSO drops in your eyes?
      I don’t mind the stinging at the concentration I used, but can you apply it without saline without feeling strong burning or even drying of the cornea? Thanks for sharing your experience.

      reply
      • Darla  January 29, 2018

        I do believe it is drying to the eye. Since my original post, I have added hexane free, cold pressed castor oil. One to two drops in each eye before using one to two drops of DMSO in each eye. I have noticed a significant improvement.

  10. Telahun  December 21, 2017

    Hello everyone,
    Two years ago I was diagnosed with wet MD in my right eye. I was told to start taking injection right away. I delayed taking the injection and started taking AREDS 2. After I consumed a bottle when I went back, the doctor told me that all the fluid has dried up and I don’t have to worry. I continued taking AREDS 2 for few more months and stopped. The distortion came back. I went to Bacom Palmer Eye Institute in Miami, Florida and started taking the injection. By the way Bascom Palmer was charging my insurance close to $14,000 to give one injection. So far I have taken three injections on monthly basis. The idea that they are charging $14,000 for one injection was burning me even though it doesn’t come from my pocket.
    Recently while browsing the Internet for home remedies for my wife’s knee pain, I stumbled on DMSO. After reading and watching videos on people’s testimonies, I ordered a gallon of ultra pure 99.996% DMSO, 70% DMSO and 30% Aloe Vera. I take two drops in each eye every day and put it on my knee and shoulder for my pain. I also take about two spoonfull by mouth on an empty stomach. It is only two weeks since I started. It is hard to believe. I say to myself it is too good to be true. The cloud in my eyes, due to the onseting of cataract, has cleard out. the pain in my knee and shoulder has decreased by 50%. It is hard to believe! However, my wife see no result so far. I hope it will work for her also.
    That is my story with DMSO.
    Good luck to those who want to try it.
    Remember since DMSO directly enters you blood stream, whenever you use it on your body, make sure your body is clean. Otherwise, it will take all the dirt and sweat with it into your blood!

    reply
    • Gabriela Segura, MD  December 22, 2017

      Great testimonial! Thank you for sharing.

      reply
    • Andreas  December 22, 2017

      Thank you for sharing. Dr. Segura suggested that DMSO in the eye should be diluted to a solution of 30cc Saline + 9 cc of DMSO at 99%.
      Please clarify how you mix the 99% DMSO with the aloe, in case people tried to use drops of 99% DMSO in the eye, which I believe it’s too strong. Thanks

      reply
      • Telahun  December 23, 2017

        If you search online, there aare companies that will sell you aleady mixed 70% DSMO and 30% aloe vera. Just type in Google search, “ULTRA PURE DMSO”. You get the site and choose from their product.

  11. Mark  January 22, 2018

    Hi Dr

    Do I take the solution as eye drops or in a eye cup for 30 sec?

    reply
    • Gabriela Segura, MD  January 22, 2018

      If you are going to experiment for the first time, I would see about the drops.

      reply
  12. Darlene  January 30, 2018

    I do about 30% dnso by mixing it with 10ppm colloidal silver. I just eyeball it to mix it. I have glaucoma and since using these drops, morning and night… Sometimes several times am an pm, I now have great distance vision in left eye and great close up vision in right eye. I can read the inscription inside a wedding ring, for example, very easily. I will come back and report what the doc says because time I go in for a check.

    reply
    • Mark  February 2, 2018

      Hi Darlene.

      After how long did you notice an improvement?
      I’ve been using this mixture for about a week now and yet I haven’t seen an improvement.

      reply
      • Darlene  February 5, 2018

        Not too long…I would say 7 to 10 days…

  13. Andreas  February 5, 2018

    Report.
    I have prepared and used the solution as indicated in the article:
    1. saline solution from the pharmacy (physiologic solution or sterile saline solution).
    2. in a 10cc syringe from the pharmacy, I put 30cc of saline solution into your small bottle. Then put 9 cc of your pure 99.9% DMSO solution in the small bottle.

    I have used a dropper to replicate the effect of the rinses with a cup, to have the same effect. The eyes became always red and burnt quite a lot, but I can stand it, for 20-30 seconds. It’s bearable.

    I have found that my sight improved very fast and I didn’t see as blurry inside bright lit rooms, or under strong fluorescent lights. Even reading got sharper. I thought that the increased circulation combined with other effects of DMSO, were improving the removal of metabolic byproducts of vision.

    However, after a while I felt that the eyes got drier. So much that I hesitated continuing. In the morning I moved my eyes right and left and it almost felt like some sand was stuck on the surface of the eye balls. I had to use regular eye drops to help add some moisture.

    I have also tried aloe vera, the product “Aloe Activator” made by the brand “Forever,” one of the leading Aloe Products brands. That alone, as pure as it is, has enough citric acid to give you a stinging effect, so that you know…. I’m still not sure how best to use aloe, and I don’t wish to mix a concoction of DMSO, saline and Aloe, every time I wish to take some drops, and I would not prepare a finished bottle with the aloe mixed with aloe that remains mixed for days.

    I hope this helps and I hope to read more detailed reports by others, and what Dr Segura would do, if she was to try the same thing. I understand she can’t give personal advice, but there are ways to go around it and still be of assistance. Thanks

    reply
    • Gabriela Segura, MD  February 5, 2018

      Since DMSO dehydrates tissues, it is probably a good idea to re-hydrate later. Either by artificial drops or some sort of friendly solution. Aloe Vera sounds alright to me.

      Happy to hear that it has helped you!

      reply
  14. Mark  February 5, 2018

    Is it ok to use water with dmso?
    I use half syringe of 99.9 dmso with water to make it into a 50/50 solution.

    reply
    • Andreas  February 6, 2018

      No. I don’t think so. Only SALINE water solutions , and as described in the article above in detail, please read it, are suited for drops or cup rinses, as suggested..

      reply
  15. Darlene  February 6, 2018

    I make a 30% dmso by mixing with colloidal silver that I make. I put this into a used eye drop bottle. My eyes barely burn upon dropping into eyes… Less than 30 sec. I also blink rapidly a after drops… No redness either.

    reply
  16. Sharon  March 8, 2018

    Could you tell me how you make your own colloidal silver to mix with the dmso? thank you

    reply
  17. Hema K  March 16, 2018

    Dear Dr.Gabriela
    I have Macular Degeneration and retinal scars in both eyes since the pasr 25 years. I am 42 now.

    I have intraocular lenses in both my eyes since past 7 years.

    Is it ok to experiment with DMSO conaidering the fact that it is a solvent. Does it have high risk of dissolvinh/disintwgrating tje IOLs.

    Many thanks for your expert advice.

    reply
  18. Clara Thomas  March 21, 2018

    My question is my mom had cataract surgery a few years ago and got back 20/25 vision. But now her vision is dimming. I don’t want to try DSMO eye drops on her because I do not know if it will harm the new lens. Does anyone one have experience in this area?

    reply
    • Darlene  March 23, 2018

      Two thoughts sunlight calling first you need to know why the dimming is taking place. It may not have anything to do with new cataracts forming. Secondly if it is new cataract forming on the new lenses then you need to find out what the material of the lenses is and see if it is compatible with DMSO or not. I think somewhere in this page there is a list of compatibility of plastics with DMSO, the ones that will not fall apart or break down with DMSO. However, again… I think you need to know what the dimming is actually being caused by.

      reply
  19. Aleena Che Ramli  April 4, 2018

    Hello doctor , at the moment I have 70 percent Dmso and 30 percent aloe .. do you think its ok for me to apply it around the eyes and eyelid ? Will it work the same .. I have glaucoma and cataract .. I only have 10 percent vision left .. hope Dmso can hel me to restore my vision ..

    reply
    • Gabriela Segura, MD  April 4, 2018

      It is not the same, but you might see some benefits. For face application, no greater than a 50% concentration is advised. It can irrititate the eyelids which are quite sensitive.

      reply
      • Aleena Che Ramli  May 1, 2018

        Thank you for your reply Dr Segura .. I wonder what type of eyedrop bottle that I can use for the 50 percent dmso 50 percent distilled water to drop in the eyes ? Do you think i can recycle the empty eyedrop bottle?

      • Gabriela Segura, MD  May 1, 2018

        Wash it in hot water for sterilization, should do.

  20. Tim  May 22, 2018

    I ordered 2 16oz bottles of this stuff and getting colloidal silver and going to experiment the hell out of this stuff on MD eyes knees and carpal tunnel , tinnitus , get back soon .

    reply
  21. Robert Vonheck  June 8, 2018

    VERY IMPRESSED BY THE ANECDOTAL CONTRIBUTIONS OF THIS POST BY THE SAGE Med.Dr.- G.SEQURA…
    ~Am a white-male industrial-designer born-10/1935, do not believe in wearing eyeglasses, and was alarmed to suddenly discover my left-eye rapidly loosing vision likely due to a type-2 Diabetes caused Cataract condition noticed several months ago, -to the point that the cloudy-occlusion made it impossible to see to drive in daylight via that left-eye alone. In the past month i have been topically administering pharmaceutically-pure Caster-oil via eye-dropper before sleeping at night, and find the Cataract is being dissolved markedly to the degree that i can now fully see the PC-screen as a blurry-image (-can tell there are 8-pica font here in this thread, -but cannot distinguish the font-mage sufficiently as to read what i am typing here via said afflicted left-eye). Accordingly, i’m encouraged that at this rate of progress, i may be able to pass my DMV/eye-test in October!
    Am including the fairly recent comment by ‘Darla’ herewith, -as i believe the nightly combination of a droplet of Castor-oil followed with a drop of DMSO can serve to accelerate the progress via ability of the solvent-DMSO to transfer the viscous Castor-oil more effectively through the Cornea-lens! Will try to report back as to results of this enhancement later in 2018… ~R.vH in sanDiego-92123.
    [Darla Jan./29/2018…. I do believe DMSO is drying to the eye; -thus since my original post, I have added hexane free, cold-pressed Castor-oil, -one to two drops in each eye, then adding one to two drops of DMSO in each eye; –and am noticing a significant visual improvement! ]

    reply
    • Gabriela Segura, MD  June 9, 2018

      Wonderful testimonial! Thank you for sharing and please let us know how it goes.

      reply
    • Darla McLain  June 9, 2018

      Darla here. I am so pleased to hear of the success you are experiencing with DMSO and hexane-free, cold-pressed castor oil application for your cataract. I share so others might have some measure of success in battling the things that are afflicting our eyesight. Thanks for posting.

      reply

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